Taylor & Francis

In this special episode of Talking techniques, one of two recorded at Neuroscience 2022, we speak to Tim Harris (Howard Hughes Medical Institute, VA, USA). Tim is the creator of Neuropixels, neural recording probes inserted into the brains of animal models, which allow researchers to collect signals from hundreds of individual neurons in different brain regions simultaneously over extended periods of time.

Here, he shares the story behind his creation and details how they have changed the data collection landscape in Neuroscience. Tim also considers every inventor’s greatest concern: has his invention led to purely positive outcomes for the field? By enabling the collection of huge datasets have Neuropixels led to studies that bury findings in vast swathes of data or have they enabled researchers to collect enough information to discover the emphatic truth?

Listen now to find out Tim’s opinions on these contentious debates in neuroscience and get key tips for utilizing neuropixels! 

Contents:Introduction: 00:00-03:00Tim's symposium on the capabilities of Neuropixels: 03:00-04.00Key takeaways from the symposium: 04:00-07:45The story of the development of neuropixels: 07:45-13:50Best practice tips for utilizing neuropixels: 13:50-15:15Challenges of utilizing neuropixels: 15:15-15:50Addressing the challenge of big data and sharing uncertainty: 15:50-17:30How neuropixels have accelerated neuroscience data generation: 17:30-19:30 

In this episode of Talking Techniques, we head to the Ecuadorian rainforest to chat about the use of sequencing in conservation with Zane Libke, a field researcher based at Sumak Kawsay In Situ (Pastaza, Ecuador). Zane discusses how he turned his fascination with nature into a career, his current work using nanopore sequencing technologies to find undescribed species and helping train future field researchers.

We also explore the benefits of fighting biodiversity in a more local-centric way and using research to protect the area from exploitative companies.

Contents:Intro: 00:00–01:35Zane’s work at Sumak Kawsay In Situ: 01:35–05:05Turning a fascination with nature into a career: 05:05–08:20The importance of sequencing for conservation: 08:20–12:25Technologies being used to sequence in the field: 12:25–14:15Portable nanopore sequencing with the MinION: 13:15–15:35Exporting samples means exporting opportunity: 15:35–18:40The sequencing workflow: 17:40–24:50Data processing: 24:50–27:45Using these technologies to find undescribed species: 27:45–32:20Fighting biodiversity loss in a more local-centric way: 32:20–34:55Using research to protect the area from exploitation: 34:55–38:50What the future holds: 38:50–43:22

In this episode of Talking Techniques, we head to the Ecuadorian rainforest to chat about the use of sequencing in conservation with Zane Libke, a field researcher based at Sumak Kawsay In Situ (Pastaza, Ecuador). Zane discusses how he turned his fascination with nature into a career, his current work using nanopore sequencing technologies to find undescribed species and helping train future field researchers.

We also explore the benefits of fighting biodiversity in a more local-centric way and using research to protect the area from exploitative companies.

Contents:Intro: 00:00–01:35Zane’s work at Sumak Kawsay In Situ: 01:35–05:05Turning a fascination with nature into a career: 05:05–08:20The importance of sequencing for conservation: 08:20–12:25Technologies being used to sequence in the field: 12:25–14:15Portable nanopore sequencing with the MinION: 13:15–15:35Exporting samples means exporting opportunity: 15:35–18:40The sequencing workflow: 17:40–24:50Data processing: 24:50–27:45Using these technologies to find undescribed species: 27:45–32:20Fighting biodiversity loss in a more local-centric way: 32:20–34:55Using research to protect the area from exploitation: 34:55–38:50What the future holds: 38:50–43:22

In this episode of Talking Techniques, we head to the Ecuadorian rainforest to chat about the use of sequencing in conservation with Zane Libke, a field researcher based at Sumak Kawsay In Situ (Pastaza, Ecuador). Zane discusses how he turned his fascination with nature into a career, his current work using nanopore sequencing technologies to find undescribed species and helping train future field researchers.

We also explore the benefits of fighting biodiversity in a more local-centric way and using research to protect the area from exploitative companies.

Contents

·        Intro: 00:00–01:35

·        Zane’s work at Sumak Kawsay In Situ: 01:35–05:05

·        Turning a fascination with nature into a career: 05:05–08:20

·        The importance of sequencing for conservation: 08:20–12:25

·        Technologies being used to sequence in the field: 12:25–14:15

·        Portable nanopore sequencing with the MinION: 13:15–15:35

·        Exporting samples means exporting opportunity: 15:35–18:40

·        The sequencing workflow: 17:40–24:50

·        Data processing: 24:50–27:45

·        Using these technologies to find undescribed species: 27:45–32:20

·        Fighting biodiversity loss in a more local-centric way: 32:20–34:55

·        Using research to protect the area from exploitation: 34:55–38:50

·        What the future holds: 38:50–43:22

In this In the Zone podcast, we explore how precision oncology is currently utilized in the bioanalytical field, the use of liquid biopsies to support these studies and the major challenges impacting drug development.

Hello and welcome to the latest episode of OC Talks, the podcast from Oncology Central. I am Jade Parker, Senior Editor of Oncology Central. Today I am joined by Laetitia Decroix Guilloux, Vice President of Oncology and EMEA Commercial Strategy Lead at Janssen, to discuss the patient journey through lung cancer, examine the lung cancer paradigm, and how the cancer research community can holistically address unmet needs in cancer.

In this Tech blast episode, we talk CAR-T cell development for cancer immunotherapies with Ritwika Biswas, Product Scientist for Sino Biological. We cover some of the latest developments in the field, the advantages of CAR-T over other immunotherapies and selecting the perfect CAR-T antigen, amongst a whole host of different aspects in the field.

Contents

Introduction: 00:00-00:30

Core principles of cancer immunotherapy: 00:30-02:00

Explaining cancer immunity: 02:00-03:20

Distinguishing CAR-T from native T cells: 03:20-04:40

CAR-T antigen targets: 04:40-06:00

Techniques for engineering CAR-T cells: 06:00-08:00

Introducing off the shelf CAR-T cells: 08:00-09:45

Addressing challenges in off the shelf CAR-T: 09:45-11:30

Current status of CAR-T therapies: 11:30-12:55

Advantages of CAR-T cell therapy over other immunotherapies: 12:55-15:25

The future of CAR-T: 15:10-18:10

NNM-2021-0076 podcast by Taylor & Francis Group

In this interview we explore what minimal residual disease (MRD) is in hematological malignancies and how MRD is currently monitored. The interviewees also explain their recent research published in Nanomedicine, which investigates a novel tool to monitor hematological malignancies.

This month on Editor’s Picks, hear about the impacts of aerobic exercise on tumor microenvironments, the science behind female pleasure, how bacteria could be used to make whipped cream and the bacteria that could survive 280 million years on Mars!