PyRx is a Virtual Screening software for Computational Drug Discovery that can be used to screen libraries of compounds against potential drug targets. Sarkis had registered the PyRx project at SourceForge in 2009.

Full episode at twit.tv/floss/464

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Microsoft may have just revealed what we will call the Windows 10 Productivity Update. Build 17063 for the Fast Ring has a metric ton of new features. This is almost certainly the next version of Windows 10. Key new feature: Timeline.

For the full episode, visit twit.tv/ww/549

Hosts: Leo Laporte, Mary Jo Foley, and Paul Thurrott

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Using social media and memes to win a campaign requires throwing a lot of spaghetti on the wall.

Watch the full episode here:
https://twit.tv/twig/436

Hosts: Leo Laporte, Stacey Higginbotham, and Jeff Jarvis

Guest: Joan Donovan

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George Thomas explains audio gain staging, and why it is important when connecting your components.

For the full episode, visit twit.tv/hn/330

Host: George Thomas

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Leo Laporte and Megan Morrone discuss the Drafts app for iPhone, iPad, and Apple Watch. Take notes anywhere on any iOS device and share them on social media or send a direct message. Great for Bullet Journalers who want to keep track of their notes on their devices.

Full episode at twit.tv/ios/374

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We now know the whole backstory behind Mirai, the most sophisticated botnet to date which was responsible for originating the many largest, most potent and devastating DDoS bandwidth attacks ever seen. It was three Minecraft playing college kids running a profitable Minecraft server who wanted to blast competing Minecraft hosting servers off the Net in order to obtain their competitors' user bases.

Watch the full episode here:
https://twit.tv/sn/642

Hosts: Leo Laporte and Steve Gibson

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Rene's first impressions of the iMac Pro convinces Leo to buy one.

For the full episode, visit twit.tv/mbw/589

Hosts: Leo Laporte, Rene Ritchie, Andy Ihnatko, and Alex Lindsay

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Jason Howell, Ron Richards, Florence Ion and guest Gina Trapani talk about some of their favorite Android-related things from 2017 including the Google Home Mini.

For the full episode, visit twit.tv/aaa/348

Hosts: Jason Howell, Florence Ion, and Ron Richards

Guest: Gina Trapani

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Chris Marquardt has a list of great photography gifts just in time for the holidays.

Watch the full episode here:
https://twit.tv/ttg/1449

Host: Leo Laporte

Guest: Chris Marquardt

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FCC cancels Net Neutrality and Ajit Pai mocks protesters. What next?

Watch the full episode here:
https://twit.tv/twit/645

Host: Leo Laporte

Guests: Owen JJ Stone, Harry McCracken, and Dan Gillmor

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