In this deeply charming and humorous talk, DJ and self-professed pirate Tom Nash meditates on how facing adversity due to disability invited patience, ambition and pragmatism into his life in enlightening, unexpected ways. "We all have unique weaknesses," he says. "If we're honest about what they are, we can learn how to best take advantage of them."

What if we could "grow" clothes from microbes, furniture from living organisms and buildings with exteriors like tree bark? TED Fellow Suzanne Lee shares exciting developments from the field of biofabrication and shows how it could help us replace major sources of waste, like plastic and cement, with sustainable and eco-friendly alternatives.

Dan Clay was worried about being dismissed as "too gay" at work, so he dialed down his personality. But then his alter ego, Carrie Dragshaw, went viral online. Here's what happened next.

Scientists predict climate change will displace more than 180 million people by 2100 -- a crisis of "climate migration" the world isn't ready for, says disaster recovery lawyer and Louisiana native Colette Pichon Battle. In this passionate, lyrical talk, she urges us to radically restructure the economic and social systems that are driving climate migration -- and caused it in the first place -- and shares how we can cultivate collective resilience, better prepare before disaster strikes and advance human rights for all.

What if you never had to fill out paperwork again? In Estonia, this is a reality: citizens conduct nearly all public services online, from starting a business to voting from their laptops, thanks to the nation's ambitious post-Soviet digital transformation known as "e-Estonia." One of the program's experts, Anna Piperal, explains the key design principles that power the country's "e-government" -- and shows why the rest of the world should follow suit to eradicate outdated bureaucracy and regain citizens' trust.

Past generations found a company to work for and then stayed there for decades. But today, we rarely stay in the same job (let alone on the same career path) and we don't rely on a single income stream. The tools and resources are out there for us to do our own thing, and more of us are going with the entrepreneurial spirit -- even if it's on the side of a traditional job. Podcaster and marketer Nicaila Matthews Okome helps survey the scene.

The UN predicts that antimicrobial resistance will be our biggest killer by 2050. "That should really scare the hell out of all of us," says bioprocess engineer Leon Marchal. He's working on an urgently needed solution: transforming the massive, global animal feed industry. Learn why the overuse of antibiotics in animal products, from livestock feed to everyday pet treats, has skyrocketed worldwide -- and how we can take common-sense measures to stave off a potential epidemic.

Tobacco use remains the leading cause of preventable disease and death in the United States, killing more people each year than alcohol, AIDS, car accidents, illegal drugs, murder and suicide combined. Follow health policy expert Mitch Zeller into the murky depths of the tobacco industry as he details the sordid history of nicotine addiction -- and invites us to imagine a world where policy change helps stop people from becoming addicted in the first place.

How can we tap into the potential of all students, especially those who come from disadvantaged backgrounds? Sociologist Anindya Kundu invites us to take a deeper look at the personal, social and institutional challenges that keep students from thriving in the United States -- and shows how closing this "opportunity gap" means valuing public education for what it really is: the greatest investment in our collective future.

How can we tap into the potential of all students, especially those who come from disadvantaged backgrounds? Sociologist Anindya Kundu invites us to take a deeper look at the personal, social and institutional challenges that keep students from thriving in the United States -- and shows how closing this "opportunity gap" means valuing public education for what it really is: the greatest investment in our collective future.