There's no better way to stop a disease than to catch and treat it early, before symptoms occur. That's the whole point of medical screening techniques like radiography, MRIs and blood tests. But there's one medium with overlooked potential for medical analysis: your breath. Technologist Julian Burschka shares the latest in the science of breath analysis -- the screening of the volatile organic compounds in your exhaled breath -- and how it could be used as a powerful tool to detect, predict and ultimately prevent disease.

You know the "forgotten middle": they're the students, coworkers and regular people who are often overlooked because they're seen as neither exceptional nor problematic. How can we empower them to reach their full potential? Sharing her work helping young people get to and through college, social activist Danielle R. Moss challenges us to think deeper about who deserves help and attention -- and shows us how to encourage those in the middle to dream big.

Is women's sexuality more complicated than men's? Well, not really, no, says author Sarah Barmak. In this frank, eye-opening talk, she shows how a flawed understanding of the female body has shaped this discussion for centuries. She debunks some age-old myths (you're welcome) and offers a richer definition of pleasure that gets closer to the simple truth about women's sexuality.

The path to skill around the globe has been the same for thousands of years: train under an expert and take on small, easy tasks before progressing to riskier, harder ones. But right now, we're handling AI in a way that blocks that path -- and sacrificing learning in our quest for productivity, says organizational ethnographer Matt Beane. What can be done? Beane shares a vision that flips the current story into one of distributed, machine-enhanced mentorship that takes full advantage of AI's amazing capabilities while enhancing our skills at the same time.

"Where does it hurt?" It's a question that activist and educator Ruby Sales has traveled the US asking, looking deeply at the country's legacy of racism and searching for sources of healing. In this moving talk, she shares what she's learned, reflecting on her time as a freedom fighter in the civil rights movement and offering new thinking on pathways to racial justice.

What job is best for a young man who's been a tennis ace, a cross-country traveler, a chemistry nerd and an NFL draftee? How about ... astronaut? Leland Melvin tells the story of the challenges he's accepted and the opportunities he's seized -- and how they led him to the International Space Station and a whole new perspective of life on earth. (Contains mature content)

Did you know that almost 150 million people worldwide are born intersex -- with biology that doesn't fit the standard definition of male or female? (That's as many as the population of Russia.) At age 10, Emily Quinn found out she was intersex, and in this wise, funny talk, she shares eye-opening lessons from a life spent navigating society's thoughtless expectations, doctors who demanded she get unnecessary surgery -- and advocating for herself and the incredible variety that humans come in. (Contains mature content)

In this passionate call to action, 16-year-old climate activist Greta Thunberg explains why, in August 2018, she walked out of school and organized a strike to raise awareness of global warming, protesting outside the Swedish parliament and grabbing the world's attention. "The climate crisis has already been solved. We already have all the facts and solutions," Thunberg says. "All we have to do is to wake up and change."

What does it take to build a national movement? In a captivating conversation with TEDWomen curator Pat Mitchell, Marian Wright Edelman reflects on her path to founding the Children's Defense Fund in 1973 -- from the early influence of growing up in the segregated American South to her activism with Dr. Martin Luther King Jr. -- and shares how growing older has only made her more radical.

The Montreal Protocol proved that the world could come together and take action on climate change. Thirty years after the world's most successful environmental treaty was signed, atmospheric scientist Sean Davis examines the world we avoided when we banned chlorofluorocarbons -- and shares lessons we can carry forward to address the climate crisis in our time.