403 The New HDFN Guidelines: A Historic Moment for Families
In this historic episode of the Allo Podcast from the Allo Hope Foundation, hosts Bethany Weathersby and Molly Sherwood celebrate the release of new evidence-based, expert-backed, and patient-informed guidelines for the prevention and management of Hemolytic Disease of the Fetus and Newborn (HDFN). They discuss why these comprehensive guidelines were urgently needed to address longstanding care gaps, highlight key prenatal and neonatal recommendations that could save lives, and share the unique collaborative process behind their creation. Listeners are encouraged to access and implement these guidelines to improve outcomes for alloimmunized families.
Watch this episode on YouTube
Access all guidelines resources on our guidelines landing page (we upload the published manuscripts and associated resources as they become available): https://allohopefoundation.org/clinical-practice-guidelines/
Pregnancy management guidelines: Moise KJ, Markham KB, Spinella PC, Sherwood MR, Robinson KA, Wilson LM, Malone J, Espinoza J, Dizon-Townson D, Mercer L, Miller R. A Clinical Practice Guideline for the Management of Pregnancy Alloimmunized to Red Blood Cell Antigens. JAMA Network Open. 2025 Nov 3;8(11):e2544649-. Available here. Note that additional practice points are in the supplemental content. To access all recommendations, practice points, and their rationale, we recommend clicking “supplemental content”, downloading the file, and accessing Table 4. This provides all information in one table for easy printing and reference.
If you are an alloimmunized mother from any country, you are welcome in our Facebook support group called “Antibodies in Pregnancy: An AHF Support Group. Join here. https://www.facebook.com/groups/antibodiesinpregnancy
Please consider donating to AHF. If you are a listener, you know we do a lot with a little. Not sure how much will make a difference? An antibody screen in Kenya costs $13 USD. A dose of RhIG for a mother who cannot afford it is $80 USD. Click here to make a one-time or recurring donation.
Our most sincere thank you to all clinicians and patients involved in the guidelines development process, including: Philip Spinella, MD; Christine Leeper, MD; Molly Sherwood; Bethany Weathersby, MEd; Mark Yazer, MD; Cassandra Josephson, MD; Jennifer Andrews, MD; Kenneth Moise Jr, MD; Timothy Bahr, MD; Allison Ayapantecatl; Nick Carr, DO, FAAP; Ravi Patel, MD; Robert Christensen, MD; Sarah Ilstrup, MD; Jon Watchko, MD; Karen Robinson, PhD, MSc; Lisa Wilson, ScM; Anthony Sciscione, DO; Donna Dizon-Townson, MD; Jimmy Espinoza, MD, Msc; Juan González Vélez MD, PhD; Kara Markham, MD; Laura Mercer, MD, MBA, MPH; Leonardo Pereira, MD, M.C.R.; Russell Miller, MD; Saul Snowise, MD; Alireza Shamshiraz, MD; Thomas Trevett, MD; Andre Cap, MD, PhD; Jeanne Hendrickson, MD; Paul Ness, MD; Ross Fasano, MD; Stella Chou, MD; Alyssa Ziman, MD; Barbara Gaines, MD; Bryan Cotton, MD, MPH; Denis Snegovskikh, MD; Donald Jenkins, MD; Frank Guyette, MD; Jason Sperry, MD; Jay Malone, MD, MS, PhD; COL Jennifer Gurney, MD; Joseph Sakran, MD, MPA, MPH; Juan Duchesne, MD; Katie Shanahan, CPNP; Nancy Dunbar, MD; Pampee Young, MD; Rich Gammon, MD; Susan Stern, MD; CAPT Travis Polk, MD
