The AMR Studio

Happy month of May! Happy month of May! In this one-health oriented episode we bring you the work of Carl-Fredrik Flach, who is an expert on sewage surveillance applied to AMR. In this interview, we chat with him about the overall role of the environment in AMR, what its dimensions are, and learn how sewage surveillance could be an asset to drive empirical treatment, especially in poor-resource settings. In the news section, we bring you a recent article looking into the potential effect of water chlorination in the development of children's microbiome, and a study just presented at the European Congress of Clinical Microbiology & Infectious Diseases showing evidence of spread of C. difficile between humans and animals. We hope you enjoy this hour with us, and see you back soon!

Check relevant links in the show notes at www.uac.uu.se/the-amr-studio/episode38/. Follow our updates on twitter on www.twitter.com/uac_uu with #theAMRstudio hashtag! Theme music by Henrik Niss: www.tinyurl.com/henriknissspotify.

Welcome to our slightly delayed April episode! For this one, we bring you an interview with Dr. Celia Souque, an evolutionary biologist with a love for board games. We talk with her about evolution, antibiotic resistance and her great outreach board game project "Drugs vs. bugs" where she worked to design not only an educational tool, but also a beautiful, fun, and engaging game for anyone to play. In the news section, we first comment on a recent research article looking into the role of silver in re-sensitizing colistin-resistant bacteria. Then we move into a recent review paper making a case for the how-to, relevance, and importance of qualitative research in the field of antimicrobial stewardship. Two different but equally interesting reads. Are you ready? Let's dive in!

Check relevant links in the show notes at www.uac.uu.se/the-amr-studio/episode37/. Follow our updates on twitter on www.twitter.com/uac_uu with #theAMRstudio hashtag! Theme music by Henrik Niss: www.tinyurl.com/henriknissspotify.

For this month of March, we bring you an interview with Mr. Michael Craig, director of the CDC's Antibiotic Resistance Coordination and Strategy, where we learn more about the role and work of public health agencies, how the CDC works in its strategy against antibiotic resistance, and the importance of prevention. In our news section, we present to you a recent publication on how the WHO antimicrobial resistance global action plan and the COVID-19 pandemic have impacted the global consumption of antimicrobials, and an article just published by one of our PhD students, investigating the mechanisms of metronidazole resistance in Giardia intestinalis. Hope you enjoy!

Check relevant links in the show notes at www.uac.uu.se/the-amr-studio/episode36/. Follow our updates on twitter on www.twitter.com/uac_uu with #theAMRstudio hashtag! Theme music by Henrik Niss: www.tinyurl.com/henriknissspotify.

Happy 2022 to you all! We are glad start a new year with you with this episode. This time, we bring you an interview with our first UAC PhD graduate, Christer Malmberg, who defended his industry-PhD thesis last year, where he developed a new rapid method of testing antibiotic susceptibility. We talk about his experience throughout his studies, what this new method brings to the table, and what he wishes for the future. In the news section, we continue talking about diagnostics, looking into a recent study that explores machine learning and the readily available MALDI-TOF system to provide early information that can help guide treatment recommendations for infections. We also talk about the new seminal paper published last month in The Lancet, presenting the most up-to-date and comprehensive data on the global burden of AMR. We hope you enjoy!

Check relevant links in the show notes at www.uac.uu.se/the-amr-studio/episode35/. Follow our updates on twitter on www.twitter.com/uac_uu with #theAMRstudio hashtag! Theme music by Henrik Niss: www.tinyurl.com/henriknissspotify.

Welcome to another regular episode at The AMR Studio! We are happy to be back with our interviews, and we bring you today the work and broad experience of professor and GARDP's Scientific Director Laura Piddock, an incredible scientists and AMR policy advocate. She shares with us her path, insights and experiences, and inspires us for the future. In the news section, we have for you two recent articles looking into new antibiotics, with two different but equally interesting approaches: chemical synthesis and mining the human proteome to search for hidden antibacterial properties. We hope you enjoy this one!

Check relevant links in the show notes at www.uac.uu.se/the-amr-studio/episode34/. Follow our updates on twitter on www.twitter.com/uac_uu with #theAMRstudio hashtag! Theme music by Henrik Niss: www.tinyurl.com/henriknissspotify.

Welcome to the second part of this special series with occasion of the antimicrobial week. To raise awareness from and to the AMR community, today we bring you another four researchers at the Uppsala Antibiotic Center that focus their work beyond the lab and development of new treatments. Listen to learn what they are working on, from farms to hospitals, and what they want you to learn!

Check out the show notes at www.uac.uu.se/the-amr-studio/episodex8/. Follow our updates on twitter on www.twitter.com/uac_uu with #theAMRstudio hashtag! Theme music by Henrik Niss: www.tinyurl.com/henriknissspotify.

Happy World Antimicrobial Awareness Week! For this year's campaign theme “Spread Awareness, Stop Resistance” we thought to tackle the concept of “awareness” from a different angle. We believe that awareness of the work of others within the AMR community is also important, and that sharing the understanding, viewpoints, and perspectives of AMR professionals can have a great impact on the work that we all do. In this first episode of two, we sat down to talk to five researchers at the Uppsala Antibiotic Center that are working on different parts of the science needed to bring new treatments to the market. Stay tuned for the second episode coming later!

Check out the show notes at www.uac.uu.se/the-amr-studio/episodex8/. Follow our updates on twitter on www.twitter.com/uac_uu with #theAMRstudio hashtag! Theme music by Henrik Niss: www.tinyurl.com/henriknissspotify.

Welcome to another month with the AMR Studio! For this occasion, we sat down with Dr. Manica Balasegaram to talk about his path from his years as a physician to his current position as director of the Global Antibiotic Research & Development Partnership (GARDP). Listen to learn how he entered the AMR world and the aspirations and current work done at GARDP. This was such an inspirational interview! In the news section, we talk about a recent review/perspective piece on the current state and challenges of antibiotic resistance in patients with cancer, and we bring you a recent research article looking into the potential of the CRISPR-Cas system as an antimicrobial, and with insight into the potential resistance to it. We hope you enjoy and have a lovely month of October!

Check relevant links in the show notes at www.uac.uu.se/the-amr-studio/episode33/. Follow our updates on twitter on www.twitter.com/uac_uu with #theAMRstudio hashtag! Theme music by Henrik Niss: www.tinyurl.com/henriknissspotify.

Happy September to you all! Welcome to another episode of The AMR Studio, this time featuring an interview with artist Anna Dumitriu. Tune in to listen to how Anna became so interested in bacteria and antibiotic resistance that she decided to make it a central part of her artwork. We also talk about the implications of science in art, how art and science can help one-another and what she aims to create with her pieces. In the news, we bring you a recent study looking into the details of access to recently developed antibiotics (or lack of thereof) in 14 high-income countries. We hope you enjoy and have a good time with us!

Check relevant links in the show notes at www.uac.uu.se/the-amr-studio/episode32/. Follow our updates on twitter on www.twitter.com/uac_uu with #theAMRstudio hashtag! Theme music by Henrik Niss: www.tinyurl.com/henriknissspotify.

Happy month of August to you all! In this episode, we feature an interview with Dr. David Hyun, director of the antibiotic resistance project at The Pew Charitable Trusts. We start by talking about David's journey to his current position and Pew's approach to support policy change and research on AMR in the United States, before diving into their latest publication looking at antibiotic prescriptions during the first months of the COVID-19. In the news section, we cover a recent article studying the potential effects of probiotics after antibiotic treatment on the resistome of the gut microbiota. We wish you the best month ahead and hope you join us again for the next one!

Check relevant links in the show notes at www.uac.uu.se/the-amr-studio/episode30/. Follow our updates on twitter on www.twitter.com/uac_uu with #theAMRstudio hashtag! Theme music by Henrik Niss: www.tinyurl.com/henriknissspotify