Telomeres were first recognized in the late 1930s as important structures on chromosome ends. In the 1970s the sequence of these structures was identified in the ciliated protozoa Tetrahymena by Elizabeth Blackburn. In the 1980s telomerase was discovered as an enzyme that elongates telomeres and compensates for natural telomere shortening. Carol Greider, Director of Molecular Biology and Genetics, Johns Hopkins University, discusses the journey from these curiosity driven discoveries to the appreciation of the role of telomeres in human disease. Series: "UC Berkeley Graduate Lectures" [Science] [Show ID: 28053]

The Anatomy of a Scientific Discovery: Telomeres and Telomerase - Past Present and Future

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In December 2020, Jennifer Doudna received her Nobel Prize in Chemistry during a small, socially-distanced ceremony at her home - followed by takeout. The traditional celebration will have to wait until next year. A videographer and photographer captured the intimate gathering and presentation of the gold medal by Barbro Osher, Sweden’s Honorary Consul General in San Francisco, with Anna Sjöström Douagi representing the Nobel Foundation. Doudna, the Li Ka Shing Chancellor’s Chair in Biomedical and Health Sciences at UC Berkeley, was joined by her husband, Jamie Cate, UC Berkeley professor of molecular and cell biology, son, Andrew, and sister Ellen Doudna of Berkeley. Series: "UC Berkeley News" [Humanities] [Science] [Show ID: 37398]

Nobel Prize Medal Presented to Jennifer Doudna at her Berkeley Home

Jennifer Doudna, co-discoverer of CRISPR-Cas9 and winner of the 2022 Nobel Prize in Chemistry, discusses how genome editing with CRISPR technology is transforming biology. CRISPR-Cas9, an RNA-guided enzyme with remarkable abilities to recognize and cleave DNA, operates by mechanisms that both explain its biological function and provide insights into technology development. Doudna covers research into this amazing family of proteins: where they came from, how they work and how CAS-9-based technologies are revolutionizing research, biomedicine and agriculture. Series: "Frontiers of Knowledge" [Science] [Show ID: 35215]

Editing the Code of Life: Into the Future with CRISPR Technology with Jennifer Doudna - 2019 Nierenberg Prize for Science in the Public Interest

Conversations host Harry Kreisler welcomes Professor Jennifer Doudna of UC Berkeley for a discussion of her intellectual odyssey that led to the discovery of CRISPR-Cas9, a revolutionary tool for gene editing.  In the conversation, they explore the implications of CRISPR-Cas9 for agriculture, biotechnology and biomedicine. They also discuss how education and public advocacy can broaden insight into the ethical and policy dimensions of the biological revolution that is upon us. Doudna received the Nobel Prize in Chemistry in 2022. Series: "Conversations with History" [Humanities] [Science] [Show ID: 34595]

Unraveling CRISPR-Cas9 with Jennifer Doudna - Conversations with History

Most people are part-Neanderthal, the closest extinct human relative. Svante Pääbo explores human genetic evolution by analyzing preserved genetic material from the remains of ancient organisms, including Neanderthals. What can we learn from the genomes of our closest evolutionary relatives? Pääbo is an evolutionary anthropologist and pioneer of paleogenetics and the director of the Max Plank Institute of Evolutionary Genetics. He won the 2022 Nobel Prize in Medicine and was awarded the 2018 Nierenberg Award for Science in the Public Interest. Series: "Frontiers of Knowledge" [Humanities] [Science] [Show ID: 34037]

A Neanderthal Perspective on Human Origins with Svante Pääbo - 2018 Nierenberg Prize for Science in the Public Interest

The 2018 David Keeling Memorial Lecture hosts Dr. Elisabeth Holland, Professor of Climate Change and Director of the Pacific Centre for Environment and Sustainable Development at the University of the South Pacific. Dr. Holland is an internationally recognized scientist and 2007 Nobel Laureate for her work on climate change issues. Among other topics, Dr. Holland speaks on the importance of listening to the Voices of the Pacific when considering climate change and its impacts - a direct reflection of her work weaving together science, policy and traditional knowledge towards a sustainable, resilient future for Pacific communities. Series: "Jeffrey B. Graham Perspectives on Ocean Science Lecture Series" [Science] [Show ID: 33489]

The Anatomy of a Scientific Discovery: Telomeres and Telomerase - Past Present and Future

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