Michael J. Corley, Ph.D., explores groundbreaking research on aging, the role of ancient viruses in our DNA, and the impact of the gut microbiome on longevity. Corley discusses how stress, diet, and exercise influence our genetic health, highlighting the complex interplay between environmental factors and our biological systems. The conversation also touches on individualized treatment strategies and the exciting potential of microbiome science in aging research. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 40266]

What's the secret to supporting a sharp mind at any age? In this program, Dr. Nancy Isenberg discusses the latest science-based practices to promote brain health and resiliency as we age. Series: "Osher WISE: Well-being and Integrative Science for Everyone" [Health and Medicine] [Show ID: 40508]

Gordon Saxe, M.D., Ph.D., reveals the secrets to slowing down the aging process and living a healthier life. He uncovers how aging affects everything from our bones and muscles to our brain, leading to issues like memory loss, fatigue, and weakened immune responses.

How can you make choices today that could help you live longer and feel better? Saxe dives into groundbreaking research on caloric restriction, a powerful tool for extending lifespan, and how a plant-based diet can prevent chronic diseases and improve overall health. He also shares practical tips on exercise, stress management, and social connection that can help you stay sharp, strong, and energized as you age. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 40322]

Anthony Lim, M.D., J.D., explores how small, intentional steps can lead to lasting behavioral change. Lim breaks down a simple, four-step framework—awareness, intention, action, and reflection—to help people achieve their goals, whether it's improving health, forming better habits, or making positive life changes. Through real-life examples and insights from neuroscience, he emphasizes the power of connecting with your deeper "why," taking action, and practicing self-compassion. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 40323]

Examine how what we eat and how we live can promote wellness, enhance immunity, combat age-related diseases, and promote longevity. Gordon Saxe, M.D., Ph.D., and Anthony Lim, M.D., J.D., share a timeless perspective, supported by their own research and clinical experience, on how optimal nourishment, purposeful reflection, health movement, and generosity of spirit can improve age-related conditions and slow the aging process. They present evidence-based recommendations for diet and lifestyle, as well as a practical and simple framework to help foster extending healthy aging behavioral changes. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 40049]

What's the secret to supporting a sharp mind at any age? In this program, Dr. Nancy Isenberg discusses the latest science-based practices to promote brain health and resiliency as we age. Series: "Osher WISE: Well-being and Integrative Science for Everyone" [Health and Medicine] [Show ID: 40073]

Elizabeth Blackburn, Ph.D., examines the relationship between telomeres, cellular aging, and metabolic health, highlighting how telomere regulation differs between insulin-sensitive and insulin-resistant individuals. She discusses the effects of environmental factors—like glucose levels, stress hormones, and drugs—on telomere maintenance, which can disrupt cellular coordination and contribute to age-related diseases. Blackburn also shares insights from studies on hibernating lemurs, indicating that while their telomere health remains stable during metabolic slowdowns, it declines upon reactivation. Ultimately, she suggests that telomere maintenance could serve as a valuable biomarker for early signs of metabolic dysfunction, informing strategies for long-term health and resilience. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39944]

Dennis O. Clegg, Ph.D., discusses treatments for age-related macular degeneration (AMD), a condition that causes vision loss. Clegg explains that while patients often report improved vision after receiving implants, objective tests don't always confirm this. He explores the potential differences in patients' responses based on genetics and disease progression. There is also an ongoing challenge in finding the best ways to reduce immune rejection of these treatments. New trials are underway to test implants in earlier stages of the disease, and researchers are looking at different strategies like localized immunosuppression. Additionally, some studies suggest that secretions from retinal cells may help preserve vision. Overall, there are many open questions, but advances in the field offer hope for better AMD treatments. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39459]

The risk for many chronic diseases is directly linked to metabolic changes in the body and loss of muscle mass often associated with aging. In this program, Dr. Natalie Marshall focuses on the central importance of movement, strength training, and body composition to improve metabolic fitness and tips to help you get started “building muscle for life." Series: "Osher WISE: Well-being and Integrative Science for Everyone" [Health and Medicine] [Show ID: 40071]

UC Davis researchers are developing innovative technology ​​to help older adults maintain independence while staying connected with loved ones. The new I-Care platform combines task management tools with advanced sensor technology to address challenges like cognitive decline and social isolation while also reducing caregiver burnout. Watch as our experts improve the future of senior care. Series: "UC Davis News" [Health and Medicine] [Science] [Show ID: 40175]