Saying 'no' to God and godly things, to holiness and righteousness, saying 'no' to His existence, to Christians, to religion, to faith... no!
Whatever side of the faith you're on, there's an internal conflict that needs to be resolved. When life happens we may find ourselves revisiting a response we've given a long time a go. Is it worth giving ourselves pause in our current circumstances to consider if our No really should be a Yes? Could the be value in considering the reason for our first Yes, and choosing to give it again but with renewed passion and commitment?