The Biorevolution Podcast

By Louise von Stechow

The Biorevolution Podcast with Andreas Horchler and Louise von Stechow – father and daughter, journalist and biologist, talking about the technologies of the biorevolution. Can genetic engineering, sy... more

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How many episodes does The Biorevolution Podcast have?

The podcast currently has 37 episodes available.

The Biorevolution Podcast episodes:

December 01, 2023 We're doomed we're saved #17
CRISPR CAS – Life’s processing tool
Gene editing technology allows humans, for the first time, to change the code of life with a precise editing system offering the potential for curing genetic diseases. The gene editing field is moving with impressive speed: after the seminal paper on the technology was published in 2012, the Nobel Prize awarded for the technology in 2020, and the first therapy approved for treatment of blood diseases in 2023.
In this episode of We’re doomed, we’re saved Andreas Horchler and Louise von Stechow, discuss the tremendous potential of the technology, but also its darker side – the high cost of the therapeutic applications and the potential for augmenting, altering, and redesigning human genomes.
Content and Editing:
Louise von Stechow and Andreas Horchler
Disclaimer:
Louise von Stechow, Andreas Horchler and their guests express their personal opinions, which are founded on research on the respective topics, but do not claim to give medical, investment or even life advice in the podcast.
Learn more about the future of biotech in our podcasts and keynotes. Contact us here:
scientific communication: https://science-tales.com/
Podcasts: https://www.podcon.de/
Keynotes: https://www.zukunftsinstitut.de/louise-von-stechow
Image:
Vipul Jha- via Unsplash
References:
https://www.mckinsey.com/industries/life-sciences/our-insights/the-bio-revolution-innovations-transforming-economies-societies-and-our-lives
https://www.mckinsey.com/industries/life-sciences/our-insights/gene-therapy-coming-of-age-opportunities-and-challenges-to-getting-ahead
https://endpts.com/vertex-looking-to-right-their-rd-ship-flashes-data-suggesting-their-sickle-cell-crispr-therapy-is-working/
https://www.nature.com/articles/d41586-023-03590-6
https://www.nature.com/articles/d41586-023-01389-z
https://www.nytimes.com/2005/07/03/books/chapters/more-than-human.html
https://sciencehistory.org/stories/magazine/the-death-of-jesse-gelsinger-20-years-later/
https://innovativegenomics.org/news/crispr-clinical-trials-2023/
https://answers.childrenshospital.org/crispr-gene-editing/
https://www.fda.gov/vaccines-blood-biologics/cellular-gene-therapy-products/approved-cellular-and-gene-therapy-products
...more
42min
November 01, 2023 We're doomed we're saved #16
Synthetic Biology - Rewriting Life
Synthetic biology - the artificial creation of biological molecules, cells, and even organisms - has the potential to revolutionize biotechnology and agriculture, allowing for the creation of novel biomaterials and fuels, opening new opportunities for DNA-based information storage and computation, and even aiding in the exploration and colonization of space. The first synthetic bacterium was created about ten years ago, and since then, the technologies supporting synthetic biology have become faster, cheaper, and more innovative. With the assistance of artificial intelligence, synthetic biology could unlock vast potential, recognized by various industries. Synthetic biology could also enable bad actors to create harmful microbes.
In the 16th episode of "We're Doomed We're Saved," Andreas Horchler and Louise von Stechow discuss the potential, risks, and some fascinating applications of synthetic biology.
Content and Editing:
Louise von Stechow and Andreas Horchler
Disclaimer:
Louise von Stechow, Andreas Horchler and their guests express their personal opinions, which are founded on research on the respective topics, but do not claim to give medical, investment or even life advice in the podcast.
Learn more about the future of biotech in our podcasts and keynotes. Contact us here:
scientific communication: https://science-tales.com/
Podcasts: https://www.podcon.de/
Keynotes: https://www.zukunftsinstitut.de/louise-von-stechow
Image:
Brett Jorden- via Unsplash
References:
https://www.nature.com/scitable/blog/bio2.0/artemisinin_a_synthetic_biology_success/
https://www.news.com.au/technology/science/space/designers-blend-bacteria-and-organic-technology-into-conceptual-grow-to-wear-space-suit-line/news-story/b843c57c29d889610c236a4c7accc665
https://pubmed.ncbi.nlm.nih.gov/20488990/
https://www.newscientist.com/article/2272899-artificial-life-made-in-lab-can-grow-and-divide-like-natural-bacteria/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7153315/
https://link.springer.com/chapter/10.1007/978-981-19-9891-1_3
https://news.mit.edu/2021/dna-data-storage-0610
https://wyss.harvard.edu/news/save-it-in-dna/
https://pubmed.ncbi.nlm.nih.gov/31819259/
https://www.nasa.gov/space-synthetic-biology-synbio/
https://pubmed.ncbi.nlm.nih.gov/30929030/
https://chemistry-europe.onlinelibrary.wiley.com/doi/abs/10.1002/cbic.202000091
...more
41min
October 02, 2023 We're doomed we're saved #15
Big data in pharma - From garbage to gold
In our data-heavy age, data becomes a treasure, a currency, a valuable good. This is true especially for the biotech and pharmaceutical industries, where data can inform the development of novel drugs. But should own biomedical data – and where should the lines between privacy and patient benefit be drawn?
In the new episode of We’re doomed, we’re saved, Andreas Horchler and Louise von Stechow discuss new strategies of data sharing and ownership in biomedicine and pharma.
Content and Editing:
Louise von Stechow and Andreas Horchler
Disclaimer:
Louise von Stechow, Andreas Horchler and their guests express their personal opinions, which are founded on research on the respective topics, but do not claim to give medical, investment or even life advice in the podcast.
Learn more about the future of biotech in our podcasts and keynotes. Contact us here:
scientific communication: https://science-tales.com/
Podcasts: https://www.podcon.de/
Keynotes: https://www.zukunftsinstitut.de/louise-von-stechow
Image:
Sigmund al4RJ- via Unsplash
References:
https://www.biopharminternational.com/view/big-pharma-meets-big-data
https://www.forbes.com/sites/forbesbusinesscouncil/2022/05/27/data-is-pharmas-next-blockbuster/
https://www.melloddy.eu/
https://www.pistoiaalliance.org/eventdetails/pistoia-alliances-2023-annual-usa-conference/
https://spectrum.ieee.org/icelands-giant-genome-project-points-to-future-of-medicine
https://academic.oup.com/jlb/article/8/2/lsab023/6380070
...more
34min
September 04, 2023 We're doomed we're saved #14
De-extinction - A mammoth project
The rapid spread of humans is causing many species to disappear off the face of the earth – in a so-called mass extinction. Some scientists are trying to reverse this process, by bringing back extinct species, such as the Dodo, the Passenger Pigeon, or the Wolly Mammoth.
In the 14th episode of We’re doomed, we’re saved Andreas Horchler and Louise von Stechow discuss the breeding procedures and genetic engineering techniques that might be used for brining back extinct animals. We also discuss the ethical implications from resource waste to animal welfare – and what it might mean to be the first and the last member of a (de)extinct species.
Content and Editing:
Louise von Stechow and Andreas Horchler
Disclaimer:
Louise von Stechow, Andreas Horchler and their guests express their personal opinions, which are founded on research on the respective topics, but do not claim to give medical, investment or even life advice in the podcast.
Learn more about the future of biotech in our podcasts and keynotes. Contact us here:
scientific communication: https://science-tales.com/
Podcasts: https://www.podcon.de/
Keynotes: https://www.zukunftsinstitut.de/louise-von-stechow
Image:
John Benitez- via Unsplash
References:
https://www.cnbc.com/2021/09/13/geneticist-george-church-gets-funding-for-lab-grown-woolly-mammoths.html
https://colossal.com/de-extinction/
https://www.quantamagazine.org/why-de-extinction-is-impossible-but-could-work-anyway-20220509/
https://e360.yale.edu/features/the_case_against_de-extinction_its_a_fascinating_but_dumb_idea
https://www.popularmechanics.com/science/animals/a32743456/rapid-mass-extinction/
https://www.britannica.com/video/214809/Dodo-extinct-bird-island-Indian-Ocean-human-induced-extinction
...more
36min
August 02, 2023 We're doomed we're saved #13
365 days We're doomed we're saved
**** GERMAN EPISODE ****
Ein Jahr We're doomed we're saved - seiten einem Jahr sprechen Andreas Horchler und Louise von Stechow über die Themen der Biorevolution. Wir haben über Anitbiotikaresistenzen, Biowaffen, Gentherapien, Neuroprothesen und AI gesprochen. Wir hatten spannende Gäste, wie den Mathematiker und idalab Gründer Paul von Bünau, und den Forschungs- und Entwicklungschef von Sanofi Adventis Deutschland mit denen wir über die Rolle neuer Technologien wie AI für die Medikamentenentwicklung gesprochen haben.
In dieser Folge lassen wir die erste Staffel Revue passieren und machen "A big announcment". Dies wird unsere vorerst letzte Deutsche Episode sein - in der neuen Staffel, ab September, werden wir uns auf Englisch unterhalten.
Content and Editing:
Louise von Stechow and Andreas Horchler
Disclaimer:
Louise von Stechow, Andreas Horchler and their guests express their personal opinions, which are founded on research on the respective topics, but do not claim to give medical, investment or even life advice in the podcast.
Learn more about the future of biotech in our podcasts and keynotes. Contact us here:
scientific communication: https://science-tales.com/
Podcasts: https://www.podcon.de/
Keynotes: https://www.zukunftsinstitut.de/louise-von-stechow
...more
26min
July 03, 2023 We're doomed we're saved #12
Follow the money - Die Geldquellen der Biowissenschaften
**** GERMAN EPISODE ****
Follow the money, folge dem Geld, ist eine alte Weisheit wenn man den Kern einer Angelegenheit verstehen will.
In der 12. Folge von We're doomed we're saved folgen wir diesem Weg zu den Geldquellen der Biomedizinischen Forschung, zu Regierungszuschüssen, großen Pharmaunternehmen und privaten Stiftungen, wie der Bill und Melinda Gates Foundation, die ganze Forschungszweige quasi im Alleingang finanziert. Solche privaten Geldgeber haben besonders in den USA einen großen Einfluss auf die Forschungslandschaft, obwohl ihre Auswahlkriterien und Transparenz umstritten sind und die Verbindung von Wissenschaftlern und reichen Technokraten das Vertrauen in die Wissenschaft verringern kann.
Content and Editing:
Louise von Stechow and Andreas Horchler
Disclaimer:
Louise von Stechow, Andreas Horchler and their guests express their personal opinions, which are founded on research on the respective topics, but do not claim to give medical, investment or even life advice in the podcast.
Learn more about the future of biotech in our podcasts and keynotes. Contact us here:
scientific communication: https://science-tales.com/
Podcasts: https://www.podcon.de/
Keynotes: https://www.zukunftsinstitut.de/louise-von-stechow
Image:
Andre Taissin via Unsplash
References
https://www.nature.com/articles/d41586-023-00077-2
https://sciencephilanthropyalliance.org/philanthropy-a-critical-player-in-supporting-scientific-research-alliance-blog/
https://arxiv.org/abs/2206.10661
https://www.technologynetworks.com/tn/news/science-is-becoming-less-disruptive-368887
https://sciencephilanthropyalliance.org/science-philanthropy-engagement-with-minority-serving-institutions-the-why-how-and-what/
https://www.science.org/content/article/what-kind-researcher-did-sex-offender-jeffrey-epstein-fund-he-told-science-he-died
https://www.gatesmri.org/
https://www.forbes.com/sites/siladityaray/2023/01/17/gates-foundation-ceo-defends-philanthropys-influence-on-global-health/?sh=6e4af7894be2
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736%2808%2961485-3/fulltext?version=printerFriendly
https://www.nature.com/articles/d41586-020-01452-z
https://www.wired.com/story/opinion-the-world-loses-under-bill-gates-vaccine-colonialism/
https://www.wired.com/story/opinion-the-dangers-of-relying-on-philanthropists-during-pandemics/
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736%2808%2961485-3/fulltext?version=printerFriendly
https://www.scidev.net/global/news/gates-foundation-reviews-funding-focus-after-criticism/
https://www.thelancet.com/journals/lancet/article/PIIS0140673609608850/fulltext?rss=yes
https://www.nytimes.com/2019/09/07/business/mit-media-lab-jeffrey-epstein-joichi-ito.html
https://www.theguardian.com/us-news/2019/aug/18/private-jets-parties-and-eugenics-jeffrey-epsteins-bizarre-world-of-scientists
https://www.theverge.com/2020/1/10/21060506/jeffrey-epstein-mit-report-donation-scandal-rafael-reif-investigation
https://www.nature.com/articles/s41586-022-05543-x
...more
34min
June 01, 2023 We're doomed we're saved #11
Die Zukunft der Pharmaindustrie - Neue Technologien und Modelle
**** GERMAN EPISODE ****
Wie werden neue Technologien, wie die künstliche Intelligenz die Pharmaindustrie beeinflussen? Welche neuen Modelle werden die Blockbuster der Vergangenheit ablösen?
In dieser Folge sprechen wir mit unserem Gast Professor Jochen Maas, Geschäftsführer Forschung & Entwicklung Sanofi-Aventis, Deutschland GMBH über die Zukunft der Pharmaindustrie
Content and Editing:
Louise von Stechow and Andreas Horchler
Disclaimer:
Louise von Stechow, Andreas Horchler and their guests express their personal opinions, which are founded on research on the respective topics, but do not claim to give medical, investment or even life advice in the podcast.
Learn more about the future of biotech in our podcasts and keynotes. Contact us here:
scientific communication: https://science-tales.com/
Podcasts: https://www.podcon.de/
Keynotes: https://www.zukunftsinstitut.de/louise-von-stechow
Image:
Amanda Marie via Unsplash
...more
40min
May 02, 2023 We're doomed we're saved #10
Biohackers - Die Garagenwissenschaftler
**** GERMAN EPISODE ****
Biohacker experimentieren an sich selbst, führen genetische Modifikationen durch, implantieren Mikrochips und testen neue Medikamente. Dabei bewegen sie die Wissenschaft aus den Elfenbeintürmen der Universitäten hin zu privaten Laboren, Küchen und Garagen. Dies verspricht größere Chancengleichheit und neue Möglichkeiten für Innovationen in der Wissenschaft, birgt jedoch auch die Gefahr einer mangelnden Regulierung mit unvorhersehbaren Konsequenzen.
In der neuen Folge von We’re doomed we’re saved besprechen Andreas Horchler und Louise von Stechow die Ziele und Methoden der Biohacker und stellen die Frage ob sie eine Chance ohne eine Gefahr darstellen.
Content and Editing:
Louise von Stechow and Andreas Horchler
Disclaimer:
Louise von Stechow, Andreas Horchler and their guests express their personal opinions, which are founded on research on the respective topics, but do not claim to give medical, investment or even life advice in the podcast.
Learn more about the future of biotech in our podcasts and keynotes. Contact us here:
scientific communication: https://science-tales.com/
Podcasts: https://www.podcon.de/
Keynotes: https://www.zukunftsinstitut.de/louise-von-stechow
Image:
Vivint Solar via Unsplash
References:
https://www.theguardian.com/artanddesign/architecture-design-blog/2015/aug/14/body-hackers-the-people-who-turn-themselves-into-cyborgs
https://www.wired.com/story/health-business-deprivation-technology/?utm_social-type=owned&mbid=social_twitter
https://www.theguardian.com/science/2018/sep/21/extreme-biohacking-tech-guru-who-spent-250000-trying-to-live-for-ever-serge-faguet
https://www.businessinsider.com/ray-kurzweils-immortality-diet-2015-4
https://www.medizin-transparent.at/kaeltekammer/
https://www.youtube.com/watch?v=nTwZ46QHHIM
https://www.theguardian.com/science/2017/dec/24/josiah-zayner-diy-gene-editing-therapy-crispr-interview
https://gizmodo.com/this-guy-just-injected-himself-with-a-diy-hiv-treatment-1819659724
https://www.theguardian.com/commentisfree/2022/nov/26/live-to-100-diet-lentil-broccoli-rich-immortality
https://frontlinegenomics.com/biohackers-and-diy-gene-therapy/
https://www.mdpi.com/2072-6643/11/3/673
https://www.nytimes.com/2019/03/26/style/silicon-valley-stoics.html
https://dailystoic.com/tim-ferriss/
https://www.theguardian.com/technology/2018/may/06/no-death-and-an-enhanced-life-is-the-future-transhuman
https://www.health.com/condition/rheumatoid-arthritis/cryotherapy-not-safe
https://amateurgods.substack.com/p/a-brief-history-of-biohacking?r=6q7v&utm_campaign=post&utm_medium=email
https://www.wired.com/2008/03/ff-kurzweil/
...more
39min
April 03, 2023We're doomed we're saved #9
ChatGPT - The rise of the chatbots
**** GERMAN EPISODE ****
ChatGPT, das Large Language Model von OpenAI ist in aller Munde. Von Untergangsszenarien in denen der Mensch und seine Arbeitsleistung als obsolet erklärt werden, über Lehrende, die sich fragen, wie sie Seminararbeiten bewerten sollen, bis hin zur Frage menschlicher und maschineller Kreativität – ChatGPT bewegt uns alle.
In der neuen Folge von We’re doomed we’re saved besprechen Louise von Stechow und Andreas Horchler welche Auswirkungen ChatGPT und andere Large Language Modelle für den Gesundheit Sektor und die Biotech und Pharma Industrie haben könnten und ob sie gar dabei helfen können den Code des Lebens zu verstehen oder sogar umzuschreiben.
Unterstützt werden sie dabei zum ersten Mal von einem Gast, Paul von Bünau, Mathematiker und Gründer der Firma idalab, die sich auf künstliche Intelligenzlösungen für die Biotech Industrie spezialisiert.
Content and Editing:
Louise von Stechow and Andreas Horchler
Disclaimer:
Louise von Stechow, Andreas Horchler and their guests express their personal opinions, which are founded on research on the respective topics, but do not claim to give medical, investment or even life advice in the podcast.
Learn more about the future of biotech in our podcasts and keynotes. Contact us here:
scientific communication: https://science-tales.com/
Podcasts: https://www.podcon.de/
Keynotes: https://www.zukunftsinstitut.de/louise-von-stechow
Image:
DALL-E, "Revoluting robots in the style of french revolution patinings"
References
ChatGPT overview
https://www.zdnet.com/article/chatgpt-lacked-depth-and-insight-say-prestigious-science-journal-editors/
https://time.com/6238781/chatbot-chatgpt-ai-interview/
Human vs. computer brain
https://www.weforum.org/agenda/2023/02/how-does-chatgpt-differ-from-human-intelligence/
https://www.nature.com/articles/s41598-021-95603-5
https://arxiv.org/abs/2301.06627
https://www.theatlantic.com/technology/archive/2023/01/chatgpt-ai-language-human-computer-grammar-logic/672902/
ChatGPT in Healthcare
https://radiologybusiness.com/topics/artificial-intelligence/6-ways-radiologists-can-use-chatgpt
https://www.doximity.com/docs-gpt
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9980251/?report=printable
https://www.statnews.com/2023/02/13/chatgpt-assisted-diagnosis/
https://www.babylonhealth.com/en-us/what-we-offer/chatbot
https://arxiv.org/abs/2212.14882
Reading the code of life
https://omicstutorials.com/using-chatgpt-in-bioinformatics-and-biomedical-research/
https://www.nature.com/articles/s41587-022-01618-2
https://www.freethink.com/health/ai-antibiotic-proteins
https://www.nature.com/articles/s41587-023-01705-y
ChatGPT in drug discovery
https://www.pharmavibes.co.uk/2023/02/28/chatgpt-a-chatbot-with-a-myriad-of-potential-uses-possibly-including-regulatory-affairs/
https://chemrxiv.org/engage/chemrxiv/article-details/63d56c13ae221ab9b240932f
https://www.ddw-online.com/four-ways-chatgpt-could-impact-drug-discovery-21838-202302/
The dark side of ChatGPT
https://www.forbes.com/sites/janicegassam/2023/01/28/the-dark-side-of-chatgpt/?sh=593d18384799
https://theintercept.com/2022/12/08/openai-chatgpt-ai-bias-ethics/
...more
39min
March 01, 2023 We're doomed we're saved #8
Longevity- Who wants to live forever?
GERMAN EPISODE
Seit Anbeginn der Menschheit beschäftigt uns die Frage, warum wir altern, warum wir sterben müssen. In der neuen Folge von We’re doomed, we’re saved besprechen Andreas Horchler und Louise von Stechow den neuesten biomedizinische Forschungstand zum Thema Altern und stellen die Frage ob sich das Altern verlangsamen, ja sogar aufhalten lassen wird? Wie sähe eine Welt aus, in der die Menschen 150 Jahre oder noch älter werden – was würde ein verlängertes Leben für die Art wie wir leben, lieben und arbeiten, für die Dinge, die uns wichtig sind und für unseren überstrapazierten Planeten bedeuten? Wir nehmen den Der Traum vom längeren Leben unter die Lupe und enden mit der Frage – „Who wants to live forever?“
Content and Editing:
Louise von Stechow and Andreas Horchler
Disclaimer:
Louise von Stechow, Andreas Horchler and their guests express their personal opinions, which are founded on research on the respective topics, but do not claim to give medical, investment or even life advice in the podcast.
Learn more about the future of biotech in our podcasts and keynotes. Contact us here:
scientific communication: https://science-tales.com/
Podcasts: https://www.podcon.de/
Keynotes: https://www.zukunftsinstitut.de/louise-von-stechow
Image:
Michael Lefrancois Via Unsplash
References
https://www2.deloitte.com/us/en/pages/life-sciences-and-health-care/articles/longevity-science.html
https://www.cell.com/fulltext/S0092-8674(13)00645-4
https://www.dvcstem.com/post/anti-aging-stem-cells
https://www.forbes.com/sites/forbestechcouncil/2021/05/03/will-you-live-to-200-five-levels-of-breakthroughs-in-longevity-research-you-must-know-about/
https://www.afar.org/imported/AFAR_INFOAGING_GUIDE_THEORIES_OF_AGING_2016.pdf
https://www.nature.com/scitable/knowledge/library/the-evolution-of-aging-23651151/
https://www.nature.com/articles/s41576-022-00513-5
https://www.science.org/content/article/feature-man-who-wants-beat-back-aging
https://www.mayoclinic.org/tests-procedures/bone-marrow-transplant/in-depth/stem-cells/art-20048117
https://www.fda.gov/consumers/consumer-updates/fda-warns-about-stem-cell-therapies
https://www.theguardian.com/books/2022/may/02/could-we-make-ageing-a-thing-of-the-past
https://longevity.technology/news/unity-cuts-lead-program-after-clinical-trial-fail/
...more
35min

FAQs about The Biorevolution Podcast:

How many episodes does The Biorevolution Podcast have?

The podcast currently has 37 episodes available.