Everyone wants a supplement for brain health—but most don’t do what they promise.
In this free preview of our first Ask Annie episode, Dr. Annie Fenn breaks down which supplements are actually backed by science, which ones are overhyped, and how to build a smarter, more personalized routine. The goal is not to take more. It’s to take the right things, in the right dose, for the right reason. If you'd like to listen to the full episode, come join our community as a paid subscriber at brainhealthkitchen.substack.com.
Chapters00:00 The problem with brain supplement hype
02:15 Food first—and why supplements come second
04:30 How to build a smarter supplement routine
06:00 The key labs to check before you start
09:30 Vitamin D: simple, but easy to get wrong
12:00 Omega-3s: the most important (and most messed up) supplement
14:00 B vitamins: the hidden deficiency that affects your brain
19:00 Magnesium: what actually works for sleep and the brain
30:30 Creatine: why everyone is suddenly talking about it
38:00 Flavonoids: the brain nutrients you should eat, not pill
41:30 What’s promising (but not proven yet)
49:30 Multivitamins: insurance policy or unnecessary?
51:50 NAD, peptides, and the longevity hype machine
56:00 When to take supplements (and what to take with food)
59:30 What Annie actually takes—and keeps simple
Links & ResourcesBrain Health Kitchen Substack
https://brainhealthkitchen.substack.com
Annie’s 2026 Brain Supplement Guide: need to link these
Annie’s Food Pyramid
SponsorsNeuroReserve
Maker of Relevate and Revanta, brain-focused formulations designed to support cognitive health. neuroreserve.com
Better Brain
A personalized brain health program with advanced lab testing, coaching, and tailored recommendations. betterbrain.com