The Brain Podcast

Welcome to another episode of The Brain Podcast (first for 2023!) - the official podcast for the journal Brain and sister journal Brain Communications.

In this episode, three guests joined us to discuss the article entitled: Gene variant effects across sodium channelopathies predict function and guide precision therapy.

Professor Andreas Brunklaus (first author) and Professor Stephanie Schorge (senior author) discuss their fascinating data-driven approach to better understand how mutations in sodium channels affect function with potential for precision therapy. We were fortunate to also e joined by Professor Massimo Mantegazza, who provided additional expert opinion.

Enjoy this rich, in-depth discussion!

Check out the full article on the Brain website: https://doi.org/10.1093/brain/awac006

This episode was hosted, edited and produced by Xin You Tai; co-hosted by Professor Sarosh Irani; co-produced by Joanne Bell; original music by Ammar Al-Chalabi.

Welcome to the seventh episode of The Brain Podcast - the official podcast of the journals Brain and Brain Communications.

In this episode we chat with Dr Nina M Rzechorzek, lead author of the article entitled: A daily temperature rhythm in the human brain predicts survival after brain injury

We discuss how brain temperature was measured using invasive and non-invasive methods to identify a physiological daily rhythmicity. The loss of this brain rhythm was strongly predictive of survival in patients with traumatic brain injury.

Our longest episode to date but packed with fascinating science!

Check out the full article on the Brain website: https://doi.org/10.1093/brain/awab466

This episode was hosted, edited and produced by Xin You Tai; co-hosted by Andreas Thermistecleous; co-produced by Joanne Bell; original music by Ammar Al-Chalabi.

Welcome to The Brain Podcast - the official podcast for the journal Brain and sister journal Brain Communications.

In this episode we are joined by Professor Soon-Tae Lee to discuss his review article entitled Seronegative autoimmune encephalitis: clinical characteristics and factors associated with outcomes. Read the full article on the Brain website: https://doi.org/10.1093/brain/awac166

Maarten Titulaer and Robin van Steenhoven wrote an excellent commentary on the article https://doi.org/10.1093/brain/awac338 We were lucky to have Maarten join us in this podcast discussion.

This episode was hosted, edited and produced by Xin You Tai; co-hosted by Sarosh Irani; co-produced by Joanne Bell; original music by Ammar Al-Chalabi.

Welcome to The Brain Podcast - the official podcast for the journal Brain and sister journal Brain Communications.

In this episode we are joined by Associate Professor Pavan Bhargava to discuss his review article entitled The contribution of B cells to the cortical damage in multiple sclerosis.

Read the full article on the Brain website: https://doi.org/10.1093/brain/awac233

This episode was hosted, edited and produced by Xin You Tai; co-hosted by Sarosh Irani; co-produced by Joanne Bell; original music by Ammar Al-Chalabi.

Welcome to The Brain Podcast - the official podcast for the journal Brain and sister journal Brain Communications.

In this episode we chat with Dr Georgia Melli, senior author of the article entitled: Tau protein quantification in skin biopsies differentiates tauopathies from alpha-synucleinopathies

She discusses the use of skin biopsy to quantify pathological tau protein as an accessible and useful clinical tool in the diagnosis of neurodegenerative diseases.

Check out the full article on the Brain website: https://doi.org/10.1093/brain/awac161

This episode was hosted, edited and produced by Xin You Tai; co-hosted by Sarosh Irani; co-produced by Joanne Bell; original music by Ammar Al-Chalabi.

Welcome to the third episode of The Brain Podcast - the official podcast for the journal Brain and sister journal Brain Communications.

In this episode we chat with Dr Kristiana Xhima and Professor Isabelle Aubert, lead and senior authors, respectively, of the article entitled: Ultrasound delivery of a TrkA agonist confers neuroprotection to Alzheimer-associated pathologies.

They discuss the exciting use of MRI-guided focussed ultrasound to improve blood-brain barrier penetration of a novel Alzheimer's disease therapeutic TrkA agonist.

Check out the full article on the Brain website: https://doi.org/10.1093/brain/awab460

This episode was hosted, edited and produced by Xin You Tai; co-hosted by Sarosh Irani; co-produced by Joanne Bell; original music by Ammar Al-Chalabi.

Welcome to another episode of The Brain Podcast - the official podcast for the journal Brain and sister journal Brain Communications.

We are joined by Professor Marsel Mesulam who will discuss his masterclass in clinico-pathological-neuroimaging analysis of primary progressive aphasias.

Check out the full article on the Brain website: https://doi.org/10.1093/brain/awab410

This episode was hosted, edited and produced by Xin You Tai; co-hosted by Sarosh Irani; co-produced by Joanne Bell; original music by Ammar Al-Chalabi.

Welcome to the first episode of the Brain podcast- the official podcast for the journal Brain and sister journal Brain Communications.

We are joined by Professor Roland Liblau who will tell us about his group's mouse model of narcolepsy in which autoimmune inflammation of orexinergic neurons is induced by influenza vaccination.

Check out the full article on the Brain website: https://academic.oup.com/brain/article-abstract/145/6/2018/6581499

This episode was hosted, edited and produced by Xin You Tai; co-hosted by Sarosh Irani; co-produced by Joanne Bell; original music by Ammar Al-Chalabi.