The BSH Guidelines Official Podcast

British Society Haematology Virtual Annual Scientific Meeting Guidelines Session 2021 

General Haematology Presentations Question and Answer with Eugene Oteng-Ntim and Nick Cross; hosted by Jo Howard.

British Society for Haematology Virtual Annual Scientific Meeting Guidelines Session 2021

Professor Nick Cross presents the Good Practice Paper The use genetic tests to diagnose and manage patients with myeloproliferative and myeloproliferative/myelodysplastic neoplasms, and related disorders. The good practice paper has been published.

Professor Nick Cross is Professor of Human Genetics within Medicine at the University of Southampton and Director for Wessex Regional Genetics Laboratory Salisbury.

British Society for Haematology Virtual Annual Scientific Meeting Guidelines Session 2021

Dr Eugene Oteng-Ntim presents on the draft Guidelines Management of sickle cell disease in pregnancy. The guideline is now published .

Dr Oteng-Ntim is a Consultant Obstetrician and Head of Obstetrics at Guy's and St Thomas NHS Trust Foundation. He is a Honorary Reader in Women's Health (KCL) and Honorary Associate Professor in Epidemiology and Population Health(LSHTM).

British Society Haematology Virtual Annual Scientific Meeting Guidelines Session 2021 

Haemostasis and Thrombosis Presentations Question and Answer with Keith Gomez and Will Lester; hosted by Jo Howard.

British Society for Haematology Virtual Annual Scientific Meeting Guidelines Session 2021

Dr Will Lester presents on the draft Guidelines on The Assessment of bleeding risk prior to surgery or invasive procedures.  The guidelines aims to be published by the end of 2021 early 2022.

Dr Lester is a Honorary Haematology Consultant at University Hospitals Birmingham NHS Foundation Trust and deputy chair of the BSH Haemostasis and Thrombosis Task Force. 

British Society for Haematology Virtual Annual Scientific Meeting Guidelines Session 2021

Dr Keith Gomez presents on the final draft Guidelines for the laboratory investigation of heritable disorders of platelets function. The guideline aims to be published in the next two to three months. 

Dr Gomez is an Associate Professor in Haematology and Consultant Haematologist at the Royal Free London NHS Foundation Trust and chair of the BSH Haemostasis and Thrombosis Task Force. He has extensive clinical experience in the management of bleeding disorders, such as haemophilia, and disorders of blood clotting (thrombosis).

Dr Alwyn Kotze presents a short podcast on the BSH Good Practice Paper Preoperative patient blood management during the SARS-CoV-2 pandemic

The focus of this good practice paper is to highlight the challenges in provision of elective surgical services while SARS-CoV-2 remains prevalent in communities.

Dr Kotze discusses the good practice paper in three sections:

1) How the good practice paper is produced and which evidence is taken in account doing so

2) How we think pandemic times have changed our pathways especially concentrating on remote working and how we believe teams can and should prioritise different aspects inherent in a patient blood management programme. 

3) Clinical subject matter pandemic specific on the following:

• management of preoperative anaemia 

Dr Alwyn Kotze is a Consultant Anaesthetist at Leeds Teaching Hospitals NHS Trust. Dr Kotze's clinical practices is a mixture of organ transplantation specifically liver transplants and providing other anaesthesia for surgeries. 

Dr Jonathan Sive presents a podcast on the BSH Guidelines on the diagnosis, investigation and initial treatment of myeloma. 

The objective of this guideline is to provide healthcare professionals with clear guidance on the anti‐myeloma management of patients with newly diagnosed multiple myeloma. In all cases, individual patient circumstances may dictate an alternative approach.

Dr Sive discusses the guidelines three main focus areas:

1) Initial investigation diagnosis of myeloma 

2) Choice of treatment for myeloma 

3) Post treatment consolidation therapy 

Dr Jonathan Sive is a Consultant Haematologist and the clinical service lead for myeloma at University College London Hospital (UCLH).

Dr Nilima Parry-Jones presents a podcast on the Guidelines for diagnosis and management of hairy cell leukaemia (HCL) and hairy cell variant (HCL-V).

Hairy cell leukaemia (HCL) is an uncommon, chronic B cell leukaemia, first reported as a distinct entity in the 1950s.1, 2 HCL accounts for 2% of lymphoid leukaemias, with a male predominance and median age at diagnosis of 58 years. Classical HCL and its variant form (HCL‐V) are now regarded as separate entities,3 with different cytological, haematological and immunophenotypic features. BRAF V600E mutation, present in virtually 100% of cases of classical HCL,4 is regarded as a disease‐defining event, and is absent in HCL‐V.

Dr Parry- Jones discusses the guideline in three parts:

Part 1: Clinical and laboratory features.

Part 2: Diagnostic tests and differential diagnosis including the use of molecular genetics.

Part 3: Therapeutics and response assessment.

Dr Nilima Parry-Jones is a Consultant Haematologist at the Aneurin Bevan Local Health, Wales. 

Dr Nimish Shah presents a short podcast on the BSH Guideline Frontline Management of Post-Transplantation Lymphoproliferative Disorder in Adult Solid Organ Recipient Patients. 

Dr Shah discusses the guideline in three parts:

1) PET scan and its role in PTLD

2) The management of PTLD

3) Potential new developments  

This document is an updated guideline and details the recommendations for the frontline management of adult patients with an established diagnosis of post‑transplant lymphoproliferative disorder (PTLD) following solid organ transplantation (SOT).

PTLD represents a spectrum of disorders resulting from lymphoid or plasmacytic cell proliferations that occur as a result of immunosuppression following SOT. In adult SOT recipients, PTLD is the second commonest malignancy after skin cancer and is the commonest cause of cancer-related mortality1. The reported incidence varies according to patient age, transplant type and the degree of immunosuppression. Historically, PTLD has been reported to occur most frequently in the first year following transplantation. However, more recent reports suggest that PTLD occurring late (beyond the first year) may be at least as common2–5

Dr Nimish Shah is a Consultant Haematologist at the Norfolk and Norwich University Hospital NHS Foundation Trust.