The Business of HLTH

In this episode of the Business of HLTH Podcast, Natalie sits down with Dr. Hany Demian, physician, entrepreneur, and Founder & CEO of Praesentia Healthcare and BioSpine Institute, to explore a provocative question: What if modern medicine is designed to manage disease rather than restore health?

Drawing on a career that spans surgery, emergency medicine, chronic pain management, and longevity medicine, Dr. Demian shares the experiences that led him to challenge conventional healthcare models and build a more integrated approach to patient care. He explains why he believes aging should be viewed as a modifiable biological process rather than an inevitable decline and how advances in diagnostics, regenerative medicine, and artificial intelligence are transforming the future of healthcare. 

The conversation dives into the distinction between lifespan and healthspan, the emerging science behind longevity, and why preserving energy, mobility, cognitive function, and independence may be the most important healthcare goals of the coming decades. Dr. Demian also discusses the limitations of symptom-focused medicine, the importance of addressing root causes, and how predictive care models may fundamentally reshape the patient experience. 

If you're interested in longevity, chronic pain, preventative medicine, healthcare innovation, or the future of personalized care, this episode offers a fascinating look at where medicine may be headed next.

In this episode of the Business of HLTH Podcast, Natalie sits down with Joanna Nathan, CEO and Co-Founder of Prana Surgical, to discuss the realities of building a medical technology company in one of healthcare's most complex and highly regulated fields.

Drawing on her unique journey from bioengineering and venture investing to entrepreneurship, Joanna shares how Prana Surgical was born from a critical gap in lung cancer care. As lung cancer screening identifies more patients with small, early-stage lesions, many remain trapped in a cycle of surveillance because existing surgical tools are not designed for these challenging cases.

Joanna explains how the Prana System aims to enable image-guided, minimally invasive procedures that help physicians target difficult-to-reach lung lesions while preserving healthy tissue and improving treatment precision.

The conversation explores the challenges of scaling a medtech company, balancing clinical and business risk, navigating regulatory hurdles, securing capital, and bringing new technologies into real-world hospital workflows. Joanna also reflects on Prana's milestone of safely treating its first patients and what it takes to transform an innovative idea into a clinically viable solution.

If you're interested in medical innovation, surgical oncology, healthcare entrepreneurship, or the future of precision medicine, this is an episode you won't want to miss.

In this episode of the Business of HLTH Podcast, we step beyond traditional healthcare conversations to examine the deeper forces shaping who gets sick, who receives care, and why.

Natalie sits down with Dr. Tyler B. Evans, physician, global health leader, and CEO of Wellness Equity Alliance, whose work spans refugee camps, pandemic response, and frontline care in some of the world’s most underserved communities. Drawing from decades of experience, Dr. Evans challenges the conventional view of disease, arguing that health outcomes are not just biological, but the direct result of social and political systems.

From the rise of street medicine and the realities of healthcare access to the growing crisis of distrust in public health, this conversation explores what’s broken and what it will take to rebuild it. Dr. Evans also shares insights from his book on how pandemics are shaped long before they begin, and why rethinking systems, not just treatments, is critical to the future of global health.

If you’re interested in health equity, system-level change, and the intersection of medicine, policy, and society, this is a conversation that will challenge how you think about healthcare.

In this episode of the Business of HLTH Podcast, we explore one of the most urgent challenges in modern medicine and a breakthrough that could fundamentally change how we detect it.

Natalie sits down with Mike Banville, CEO and President of ALZpath, a company at the forefront of transforming Alzheimer’s diagnostics through its proprietary pTau217 antibody. With the potential to enable simple, scalable blood tests that detect disease years before symptoms appear, this innovation could shift Alzheimer’s care from late-stage reaction to early intervention.

Mike shares how ALZpath is navigating the complex path from scientific discovery to real-world clinical adoption, working alongside global diagnostic leaders to bring this technology to patients worldwide. The conversation also dives into what it takes to scale in a highly regulated, partnership-driven ecosystem and why focus, adaptability, and execution matter at every stage.

If you’re interested in the future of diagnostics, the evolution of Alzheimer’s care, or how breakthrough science becomes accessible at scale, this is a conversation worth listening to.

In this episode of the Business of HLTH Podcast, we step inside the world of biotech innovation, where science, capital, and patient care collide.

Natalie sits down with Dr. Shalabh Gupta, Founder and CEO of Unicycive Therapeutics, whose journey spans clinical medicine, Wall Street, and the frontlines of drug development. Driven by firsthand experience treating patients, Dr. Gupta set out to tackle a critical gap in chronic kidney disease care, building a company focused on delivering practical, patient-centered solutions at scale.

With Unicycive’s lead therapeutic now under FDA review, this conversation offers a rare look at what it truly takes to bring a drug from concept to potential approval. From navigating regulatory setbacks to building credibility with investors and clinicians, Dr. Gupta shares the realities behind biotech entrepreneurship and why solving the right problem matters more than anything else.

If you’re interested in the intersection of medicine, innovation, and the business of bringing life-changing therapies to market, this is a conversation you won’t want to miss. 

In this episode of the Business of HLTH Podcast, we take a closer look at one of the most pressing and often overlooked challenges in modern healthcare: access.

As physician shortages grow, wait times stretch longer, and entire regions become medical deserts, patients are increasingly left navigating a system that struggles to meet demand. At the same time, consumer behavior is shifting, with more people actively seeking answers and taking health into their own hands.

Natalie sits down with Jim Gebhart, CEO of thelabcafe.com, who brings over three decades of experience in the medical laboratory industry. After witnessing firsthand the barriers patients face in accessing timely care, Jim set out to rethink the model entirely, building a direct-to-consumer platform designed to put diagnostic testing directly into the hands of patients.

Together, they explore the structural gaps in healthcare, the rise of self-directed care, and how expanding access to lab testing could reshape everything from early diagnosis to long-term outcomes.

If you’re interested in the future of healthcare access, patient empowerment, and where diagnostics are headed next, this is a conversation worth tuning into.

In this episode, Vincent Vu shares his powerful journey from a childhood spent barefoot in refugee camps to founding Kinnis AI — the world’s first AI-powered balance health platform. What began as a personal injury and frustration with expensive footwear evolved into a clinical-grade innovation tackling one of aging’s most urgent challenges: fall prevention.

Vincent walks us through how Kinnis is reshaping preventative care through smart insoles, computer vision, and AI tools that assess, train, and predict mobility decline before it happens. He also opens up about launching a tech company without a software background, raising capital, and why solving the right problem matters more than having the right credentials.

If you're passionate about aging in place, movement health, or the future of wearable tech — this one’s for you.

In the Season 3 premiere of The Business of HLTH Podcast, host Natalie Dolphin sits down with Anthony Boldin, founder and CEO of Life Complete, to explore how plant-based nutrition can go far beyond protein powders and buzzwords.

Anthony shares the story behind Nutrimatch, the proprietary algorithm he developed to optimize plant-based protein combinations that closely mirror human muscle tissue. He breaks down why protein match rates are key to performance and recovery, how his team is building tech that makes plant-based living simple, and what it takes to lead with vision in a crowded health market.

From product development to purpose-driven leadership, this episode is packed with insights for anyone building in health, food tech, or mission-driven wellness.

On the season finale of The Business of HLTH Podcast, host Natalie Dolphin sits down with Sara Jónsdóttir founder and CEO of Revel Cares — the first wearable underwear brand in Canada to receive medical recognition for its leak-proof technology.

Sara shares the story behind Revel’s creation, inspired by a frustrating moment during an internship, and how that personal experience fueled a mission to transform period care. From navigating the rigorous path to clinical validation to scaling a consumer product without compromising quality, Sara opens up about what it really takes to innovate in a space long overdue for disruption.

We cover:

• What “medically recognized” means (and why it matters)

• The product testing and documentation that set Revel apart

• Fundraising as a female founder in femtech

• Her vision for redefining dignity, comfort, and choice in period care

🎧 Listen now to hear how Sara is turning a moment of embarrassment into a movement for better care.

On this episode of the Business of HLTH Podcast, Kyle Dardashti, the founder and CEO of Heali, shares his personal health journey with Crohn's disease and discussed his transition from consumer tech to health tech, leading him to develop a clinical-grade AI platform that personalizes nutrition as medicine. He emphasized the importance of sustainable, root-cause solutions in health management and highlighted Heali's unique position as the only clinical-grade nutrition infrastructure on the market, designed to treat and manage various conditions through evidence-based nutrition protocols. Kyle also discussed his passion for empowering consumers through health data ownership and provided advice for entrepreneurs, emphasizing the importance of starting with personal problems, conducting market analysis, and maintaining passion and determination.