The Code Blue Debrief Podcast: A Clinical Pharmacotherapy YouTube & Podcast

The Code Blue Debrief Podcast: A Clinical Pharmacotherapy YouTube & Podcast

By Mark Nguyen, PharmD, BCEMPMedicineHealth & Fitness
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The Code Blue Debrief Podcast: A Clinical Pharmacotherapy YouTube & Podcast episodes

  • Syphilis: The Silent Infection? Comeback SZN? | Infectious Disease | #CodeBlueDebrief

    📢 207,255 cases of syphilis in the United States in 2022; that is an 80% increase since 2018 per the Centers for Disease Control and Prevention (CDC). 1.6 million cases of chlamydia, 650 reports of gonorrohea, and to add to those syphilis numbers, 3800 cases of syphilis among newborns. What are we doing? Really, we've got to do better in removing the stigma behind STIs and make treatment more accessible.

    Website: www.pharmwyze.comShop: www.pharmwyze.com/shop
    Social Links: https://links.pharmwyze.com
    DrugQueryInbox Request: https://pharmwyze.hopp.to/drugqueryinbox
    Streaming Platforms: https://pharmwyze.hopp.to/podstreams
    Patreon: https://patreon.com/PHARMWYZE
    Paypal Donation: https://pharmwyze.hopp.to/paypaldonate
    PHARMWYZE SITREP Newsletter: https://www.pharmwyze.com/sitrepnewsletter
    Harris, E. JAMA. 2023 May 16;329(19):1633.
    Tuddenham S, Hamill MM, Ghanem KG. JAMA. 2022 Jan 11;327(2):161-172.
    Korkowsi KA, Bachmann LH, Chan PA, et al. MMWR Recomm Rep. 2021 Jul 23;70(4):1-187.s
    Forrestel AK, Kovarik CL, Katz KA. J Am Acad Dermatol. 2020 Jan;82(1):17-28.
    CDC Links
    https://www.cdc.gov/std/syphilis/default.htm
    https://www.cdc.gov/tuskegee/timeline.htm#print
    Not medical advice. Educational purposes only. No relationships to report.
    #medicalschool #clinicalpearls #nursingschool #pharmacyschool #medicaleducation #pharmacist #pharmwyze #pharmfax #criticalcare #emergencymedicine #studentpharmacist #nursingstudent #medicalstudent #pharmacy #medicine #nursing #meded #shorts #rxshorts #medigram #medshed #foamed #emrx #pharmacology #pharmacokinetics #cardiology #antibiotics #neurology #patientcase #clinicalmedicine #clinicalpharmacy

    14 min
  • Thrombolytic Stroke BP Targets? Nitroglycerin with Inferior MI? TNK for PE? | Q&A | DrugQueryInbox

    🌟 Drug Query Inbox Episode 4

    - Patient Case Post Recap
    - Role of clindamycin for necrotizing fasciitis?
    - Changing anticonvulsant therapy?
    - Benefit of tenecteplase over alteplase for massive PE?
    Welcome to PHARMWYZE! Clinical pharmacotherapy content made for learners of all medicine backgrounds. Thanks for joining my video series, #DRUGQUERYINBOX. I often get questions in the comments on my social media platforms, which I'll compile into weekly to biweekly videos.
    Website: www.pharmwyze.com
    Shop: www.pharmwyze.com/shop
    Social Links: https://links.pharmwyze.com
    DrugQueryInbox Request: https://pharmwyze.hopp.to/drugqueryinbox
    Streaming Platforms: https://pharmwyze.hopp.to/podstreams
    Patreon: https://patreon.com/PHARMWYZE
    Paypal Donation: https://pharmwyze.hopp.to/paypaldonate
    PHARMWYZE SITREP Newsletter: https://www.pharmwyze.com/sitrepnewsletter
    References
    Powers WJ, Rabinstein AA, Ackerson T, et al. Stroke. 2019 Dec;50(12):e344-e418.
    Korkowsi KA, Bachmann LH, Chan PA, et al. MMWR Recomm Rep. 2021 Jul 23;70(4):1-187.
    Pantel P, Peterson CD. Ann Emerg Med. 1980 Nov;9(11):588-90.
    Javaudin F, Lascarrou JP, Bastard QL, et al. Chest. 2019 Dec;156(6):1167-1175.
    Batchelor R, Liu DH, Bloom J, et al. Catheter Cardiovasc Interv. 2020 Jul;96(1):76-88.
    Bosson N, Isakson B, Morgan JA, et al. Prehosp Emerg Care. 2019 Sep-Oct;23(5):603-611.
    Not medical advice. Educational purposes only. No relationships to report.
    #medicalschool #clinicalpearls #nursingschool #pharmacyschool #medicaleducation #pharmacist #pharmwyze #pharmfax #criticalcare #emergencymedicine #studentpharmacist #nursingstudent #medicalstudent #pharmacy #medicine #nursing #meded #shorts #rxshorts #medigram #medshed #foamed #emrx #pharmacology #pharmacokinetics #cardiology #antibiotics #neurology #patientcase #clinicalmedicine #clinicalpharmacy

    16 min
  • Septic & Anaphylactic Shock? EtOH Withdrawal & Phenobarbital? | Acyclovir Prophylaxis? | Q&A | DrugQueryInbox v3

    For this episode, we did something different than prior videos. There was a request from viewers on Instagram for a week of MEDIGRAM patient cases, so I've made a review of those post. Also, I included viewer questions that came from the comments!

    Website: www.pharmwyze.com
    Shop: www.pharmwyze.com/shop
    Social Media: linktr.ee/pharmwyze
    Patreon: https://patreon.com/PHARMWYZE
    Shopify: wearfarmd.myshopify.com
    Etsy: https://pharmwyze.etsy.com
    PHARMWYZE SITREP Newsletter: https://www.pharmwyze.com/sitrepnewsletter
    References
    Evans L, Rhodes A, Alhazzani W, et al. Intensive Care Med. 2021
    Nov;47(11):1181-1247.
    Umar Z, Ul Rasool MH, Muhammad S, et al. Cureus. 2023 Jan
    12;15(1):e33695.
    Heindenreich PA, Bozjurt B, Aguilar D, et al. Circulation. 2022 May 3;145(18):e895-e1032.
    Shaker MS, Wallace DV, Golden DB, et al. J Allergy Clin Immunol. 2020 Apr;145(4):1082-1123.
    Hoy SM. Drugs. 2018 Oct;78(15):1605-1613.
    Panchal AR, Bartos JA, Cabanas JG, et al. Circulation. 2020 Oct
    20;142(16_suppl_2):S366-S468.
    Not medical advice. Educational purposes only. No relationships to report.


    16 min
  • Grading Open Fractures & Prophylactic Antibiotics? | Infectious Disease | #CodeBlueDebrief

    🦴 Where does ceftriaxone fit in that arsenal of bug juice for that bone sticking out? How do we classify and grade open fractures? Why do guidelines recommend cefazolin and gentamicin for extensive injuries?

    Hello there, Pharmers and Friends, Mark with PHARMWYZE. I'm a board certified emergency medicine pharmacist. I make clinical pharmacotherapy content on the social medias. Thanks for joining me on the Code Blue Debrief: A Clinical Pharmacotherapy YouTube & Podcast Series. We discuss emergency medicine and critical care pharmacology and disease state management.
    Make sure to stop by my website at www.pharmwyze.com, or visit linktr.ee/pharmwyze for my SM accounts.
    Website: www.pharmwyze.com
    Shop: www.pharmwyze.com/shop
    Patreon: https://patreon.com/PHARMWYZE
    Paypal Donation: https://www.paypal.com/donate/?hosted_button_id=PTNLSD4G5X6BA
    Social Media: linktr.ee/pharmwyze
    PHARMWYZE SITREP Newsletter: https://www.pharmwyze.com/pharmacotherapy-newsletter
    AtlasVPN: http://tinyurl.com/8tahadc7
    Not medical advice. Educational purposes only. No relationships to report.
    References
    Hoff WS, Bonadies JA, Cachecho R, Dorlac WC. J Trauma. 2011 Mar;70(3):751-4.
    Rodriguez L, Jung HS, Goulet JA, et al. J Trauma Acute Care Surg. 2014 Sep;77(3).
    Vasenius J, Tulikoura I, Vainionpaa S, Rokkanen P. Ann Chir Gynaecol. 1998;87(3):224-8.
    Bankhead-Kendall B, Gutierrez T, Murry J, et al. Eur J Trauma Emerg Surg. 2019 Feb;45(1):125-129.
    #pharmacist #pharmwyze #pharmfax #criticalcare #emergencymedicine #studentpharmacist #nursingstudent #medicalstudent #pharmacy #medicine #nursing #meded #shorts #rxshorts #medigram #thelab #medshed #foamed #emrx #pharmacology #pharmacokinetics #pharmacodynamics #cardiology #neurology #infectiousdisease #mechanism #mechanismofaction #moa #drugs #ketamine #propofol #etomidate #fentanyl #rxshorts #massivetransfusion #ems #emergency #antibiotics #metabolism #antipsychotics #drugs

    11 min
  • Seizure Prophylaxis for Traumatic Brain Injuries? | Neurology | #CodeBlueDebrief

    Up to 53% of patients will develop chronic epilepsy even with seizure prophylaxis in the setting of traumatic brain injuries. How do TBIs even cause seizures? When should we give seizure prophylaxis for TBIs? What anticonvulsants are considered for this indication?
    Hello there, Pharmers and Friends, Mark with PHARMWYZE. I'm a board certified emergency medicine pharmacist. I make clinical pharmacotherapy content on the social medias. Thanks for joining me on the Code Blue Debrief: A Clinical Pharmacotherapy YouTube & Podcast Series. We discuss emergency medicine and critical care pharmacology and disease state management.
    Make sure to stop by my website at www.pharmwyze.com, or visit linktr.ee/pharmwyze for my SM accounts.
    Website: www.pharmwyze.com
    Shop: www.pharmwyze.com/shop
    Patreon: https://patreon.com/PHARMWYZE
    Paypal Donation: https://www.paypal.com/donate/?hosted_button_id=PTNLSD4G5X6BA
    Social Media: linktr.ee/pharmwyze
    PHARMWYZE SITREP Newsletter: https://www.pharmwyze.com/pharmacotherapy-newsletter
    AtlasVPN: http://tinyurl.com/8tahadc7
    Not medical advice. Educational purposes only. No relationships to report.
    References
    Ohman K, Kram B, Schultheis J et al. Neurocrit Care. 2023 Apr;38(2):345-355.
    Carney et al. Neurosurgery. 2017 Jan 1;80(1):6-15.
    Lucke-Wold et al. Seizure. 2015 Dec;33:13-23.
    DJohn J, Ibrahim R, Patel P, et al. Cureus. 2020 Jul; 12(7): e9117.
    #pharmacist #pharmwyze #pharmfax #criticalcare #emergencymedicine #studentpharmacist #nursingstudent #medicalstudent #pharmacy #medicine #nursing #meded #shorts #rxshorts #medigram #thelab #medshed #foamed #emrx #pharmacology #pharmacokinetics #cardiology #neurology #infectiousdisease #mechanism #mechanismofaction #moa #drugs #ketamine #propofol #etomidate #fentanyl #calcium #mtp #massivetransfusion #ems #emergency #antibiotics #metabolism #antipsychotics #drugs

    7 min
  • Chlamydia & Gonorrhea 2021 Antibiotic Update? | Infectious Disease | #CodeBlueDebrief

    Having a burning sensation down there after a weekend of high-risky behavior? Which antibiotics are used for chlamydia and gonorrhea? What options are available for pregnant women or true allergies for these sexually transmitted diseases?
    Chlamydia and Gonorrhea are the two most common sexually transmitted infections in the United States. There was a fairly recent update to the CDC STI Guidelines, tune in as we'll discuss the preferred agents.
    Hello there, Pharmers and Friends, Mark with PHARMWYZE. I'm a board certified emergency medicine pharmacist. I make clinical pharmacotherapy content on the social medias. Thanks for joining me on the Code Blue Debrief: A Clinical Pharmacotherapy YouTube & Podcast Series. We discuss emergency medicine and critical care pharmacology and disease state management.
    Make sure to stop by my website at www.pharmwyze.com, or visit linktr.ee/pharmwyze for my SM accounts.
    Website: www.pharmwyze.com
    Shop: www.pharmwyze.com/shop
    Patreon: https://patreon.com/PHARMWYZE
    Paypal Donation: https://www.paypal.com/donate/?hosted_button_id=PTNLSD4G5X6BA
    Social Media: linktr.ee/pharmwyze
    PHARMWYZE SITREP Newsletter: https://www.pharmwyze.com/pharmacotherapy-newsletter
    AtlasVPN: http://tinyurl.com/8tahadc7
    Not medical advice. Educational purposes only. No relationships to report.
    References
    Dukers-Muijrers N., Wolffs P.F.G., De Vries H., et. al.: Treatment Effectiveness of Azithromycin and Doxycycline in Uncomplicated Rectal and Vaginal Chlamydia trachomatis Infections in Women: A Multicenter Observational Study (FemCure). Clin Infect Dis 2019; 69: pp. 1946-1954.
    Dombrowski J.C., Wierzbicki M.R., Newman L.M., et. al.: Doxycycline Versus Azithromycin for the Treatment of Rectal Chlamydia in Men Who Have Sex With Men: A Randomized Controlled Trial. Clin Infect Dis 2021; 73: pp. 824-831.
    Dutra K, Lazenby G. An Update on Gonorrhea and Chlamydia. Obstet Gynecol Clin North Am. 2023 Jun;50(2):299-310.
    Workowski KA, Bachmann LH, Chan PA, et al. MMWR Recomm Rep. 2021 Jul 23;70(4):1-187.
    #pharmacist #pharmwyze #pharmfax #criticalcare #emergencymedicine #studentpharmacist #nursingstudent #medicalstudent #pharmacy #medicine #nursing #meded #shorts #rxshorts #medigram #thelab #medshed #foamed #emrx #pharmacology #pharmacokinetics #cardiology #neurology #infectiousdisease #mechanism #mechanismofaction #moa #drugs #ketamine #propofol #etomidate #fentanyl #calcium #mtp #massivetransfusion #ems #emergency #antibiotics #metabolism #antipsychotics #drugs

    13 min
  • Hypocalcemia, Lethal Triad, and MTP? | Resuscitation | #CodeBlueDebrief

    Make sure to reel and deal those calcium salts during Massive Transfusion Protocol (MTP). Calcium salts are arguably the most important pharmacologic agent during MTP.
    Hello there, Pharmers and Friends, Mark with PHARMWYZE. I'm a board certified emergency medicine pharmacist. I make clinical pharmacotherapy content on the social medias. Thanks for joining me on the Code Blue Debrief: A Clinical Pharmacotherapy YouTube & Podcast Series. We discuss emergency medicine and critical care pharmacology and disease state management.
    Make sure to stop by my website at www.pharmwyze.com, or visit linktr.ee/pharmwyze for my SM accounts.
    Website: www.pharmwyze.com
    Shop: www.pharmwyze.com/shop
    Patreon: https://patreon.com/PHARMWYZE
    Paypal Donation: https://www.paypal.com/donate/?hosted_button_id=PTNLSD4G5X6BA
    Social Media: linktr.ee/pharmwyze
    PHARMWYZE SITREP Newsletter: https://www.pharmwyze.com/pharmacotherapy-newsletter
    Not medical advice. Educational purposes only. No relationships to report.
    References
    Meneses E, Boneva D, McKenney M, Elkbuli A. Massive transfusion protocol in adult trauma population. Am J Emerg Med. 2020 Dec;38(12):2661-2666.
    Wray JP, Bridwell RE, Schauer SG, Schakelford SA et al. The diamond of death: Hypocalcemia in trauma and resuscitation. Am J Emerg Med. 2021 Mar:41:104-109.
    Helsoot D, Fitzgerald M, Lefering R et al. Trauma-induced disturbances in ionized calcium levels correlate parabolically with coagulopathy, transfusion, and mortality: a multicentre cohort analysis from the TraumaRegister DGU®.Crit Care. 2023 Jul 6;27(1):267.
    Vasudeva M, Mathew JK, Groombridge C et al. Hypocalcemia in trauma patients: A systematic review. J Trauma Acute Care Surg. 2021 Feb; 90(2): 396–402.
    Robinson A, Rech MA, DeChristopher PJ et al. Defining the optimal calcium repletion dosing in patients requiring activation of massive transfusion protocol. Am J Emerg Med. 2023 Aug:70:96-100.
    Borowko R, Vignon PO, Lutz N. et al. The lethal triad of hemorrhage. Rev Infirm. 2021 Aug-Sep;70(273):16-18.
    #pharmacist #pharmwyze #pharmfax #criticalcare #emergencymedicine #studentpharmacist #nursingstudent #medicalstudent #pharmacy #medicine #nursing #meded #shorts #rxshorts #medigram #thelab #medshed #foamed #emrx #pharmacology #pharmacokinetics #cardiology #neurology #infectiousdisease #mechanism #mechanismofaction #moa #drugs #ketamine #propofol #etomidate #fentanyl #calcium #mtp #massivetransfusion #ems #emergency #antibiotics #metabolism

    8 min
  • Physostigmine for Anticholinergic Toxicity? | Toxicology | #CodeBlueDebrief

    👾 Physostigmine is a reversal agent for anticholinergic toxicities. By

    inhibiting acetylcholinesterase, increased acetylcholine becomes
    available at the synapses. It is an excellent drug to reverse
    antimuscurinic poisonings. Unfortuanetely, it has a negative stigma from
    prior case reports associated with TCA deaths.
    The Akorn manufacturer went bankrupt recently, leaving the US without
    product available for the market. Recently, the FDA announced they would
    allow temporary importation from a company in Germany.
    Hello there, Pharmers and Friends, Mark with PHARMWYZE. I'm a board
    certified emergency medicine pharmacist. I make clinical pharmacotherapy
    content on the social medias. Thanks for joining me on the Code Blue
    Debrief: A Clinical Pharmacotherapy YouTube & Podcast Series. Make
    sure to hit the follow, subscribe, and notification bell as we get into
    the episode's topic. For this episode, we'll be discussing
    anticholinergic toxicity and the use of physostigmine.
    Make sure to stop by my website at www.pharmwyze.com, or visit
    linktr.ee/pharmwyze for my SM accounts.
    Website: www.pharmwyze.com
    Social Media: linktr.ee/pharmwyze
    PHARMWYZE SITREP Newsletter:
    https://www.pharmwyze.com/pharmacotherapy-newsletter
    Shop: www.pharmwyze.com/shop
    References
    Newton RW. JAMA . 1975 Mar 3;231(9):941-3.
    Pentel P, Peterson CD. Ann Emerg Med . 1980 Nov;9(11):588-90.
    Wang GS et al. Clin Toxicol (Phila). 2021 Aug;59(8):698-704.
    Watkins JW et al. J Med Toxicol. 2015 Jun;11(2):179-84.
    Fratta KA, Ginder M, Haggerty DA. The Journal of Emergency Medicine,
    Vol. 65, No. 4, pp. e366–e368, 2023
    McCoy CE, Honda R. J Educ Teach Emerg Med. 2023 Jan 31;8(1):S25-S47.
    Elkhazeen A et al. J Forensic Sci . 2023 Jan;68(1):339-342.
    Nishtala PS, Salahudeen SJ, Hilmer SN. Expert Opin Drug Saf . 2016
    Jun;15(6):753-68.
    https://www.fda.gov/drugs/drug-shortages/october-31-2023-temporary-importation-available-physostigmine-injection
    https://www.ashp.org/drug-shortages/current-shortages/drug-shortage-detail.aspx?id=721&loginreturnUrl=SSOCheckOnly


    11 min
  • Ketamine vs Etomidate for Unstable Patients? | Rapid Sequence Intubation | #CodeBlueDebrief

    Induction agents are an essential component of rapid sequence intubation. They work synergistically with neuromuscular blockers. As the paralytics relax the vocal cords for optimal conditions as the endotracheal tubes is being passed, induction agents provide amnesia and make the patient unconscious. That is an important thing to mention. How much drug does the patient really need when they're body is barely hanging on? There is such a thing as drug toxicities and we want to keep it safe. Let's briefly review these two agents.

    Hello there, Pharmers and Friends, Mark with PHARMWYZE. I'm a board certified emergency medicine pharmacist. I make clinical pharmacotherapy content on the social medias. Thanks for joining me on the Code Blue Debrief: A Clinical Pharmacotherapy YouTube & Podcast Series. Make sure to hit the follow, subscribe, and notification bell as we get into the episode's topic. We'll be discussing ketamine and etomidate for hemodynamically unstable patients for rapid sequence intubation?


    Make sure to stop by my website at www.pharmwyze.com, or visit linktr.ee/pharmwyze for my SM accounts.

    11 min
  • Max Vasopressors? ASA STEMI Dosing? Early High Dose Statins? K-hole Content? | Q&A | DrugQueryInbox v1

    #DQI (DRUGQUERYINBOX) V1

    - Is there a max dose to vasopressors?
    - What are my thoughts on ASA STEMI dosing? What if patient is on OAC and daily baby ASA?
    - Why do we give statins in the acute setting?
    - Is PHARMWYZE in the K-hole making his content?
    Make sure to stop by my website at www.pharmwyze.com, or visit linktr.ee/pharmwyze for my SM accounts.
    If you want to support the work that I do, stop by my donate page pharmwyze.com/donate or drop by the shop, pharmwyze.com/shop.


    9 min

About The Code Blue Debrief Podcast: A Clinical Pharmacotherapy YouTube & Podcast

From the publisher's feed

Welcome to PHARMWYZE, your go-to destination for engaging clinical pharmacotherapy content! Whether you're a seasoned medical professional or just starting your journey in medicine, this podcast is tailored to cater to all medicine learners. Join us for the Code Blue Debrief: A Clinical Pharmacotherapy YouTube & Podcast, where we delve into evidence-based medicine and pharmacotherapy topics specifically curated for emergency medicine and critical care learners. Tune in now and stay ahead of the curve with PHARMWYZE!