In this episode, Lama John Makransky joins us to explore the inner architecture of compassion. Drawing from his new book How Compassion Works, we discuss how Buddhist meditative practices, attachment theory, and cognitive science can come together to help us cultivate deep well-being, unconditional love, and wise responsiveness in the face of suffering. Lama John reflects on the importance of accessing “innate qualities of goodness” through inner refuge practices, the role of secure relationality in healing, and how these insights can transform not only individual experience but social engagement. Whether you’re a clinician, a meditator, or someone interested in the meeting place of science and spirituality, this conversation offers a powerful vision of compassion as a force for inner and outer liberation.

In this episode, we speak with Rick Repetti—philosopher, meditation teacher, and editor of The Routledge Handbook of the Philosophy of Meditation. We explore whether meditation can be considered a form of philosophy, how it might deepen our understanding of the mind, self, and agency, and whether a distinctly Western philosophy of meditation is emerging. Drawing on both scholarly insight and personal practice, Rick offers a compelling vision of meditation not just as a spiritual tool, but as a philosophical method in its own right.

What happens when you spend days—or even weeks—in complete darkness? In this episode, Andrew Holecek — an expert in Tibetan Buddhism, lucid dreaming, and meditation — guides us through the profound practice of dark retreats. We explore how extended time in darkness can shift perception, support mental health, and catalyze deep spiritual awakening. Blending ancient traditions with emerging science, this conversation sheds light on the hidden power of darkness and what it can teach us about waking life.

In this episode, I am joined by Adam Safron, an independent researcher with a wild range of interests—from consciousness and free will to psychedelics, artificial life, and AI alignment. With affiliations at the Institute for Advanced Consciousness Studies and Michael Levin’s lab at Tufts University, Adam brings a rare interdisciplinary lens to questions about mind, matter, and meaning. We explore how agency arises, what it means to align intelligent systems (both artificial and biological), and how compassion might be the ultimate protocol for thriving.

In this episode, we sit down with Dr. Norman Farb to discuss his new book, Better in Every Sense, co-authored with Dr. Zindel Segal, which explores how we become emotionally stuck and how to break free. Drawing from cutting-edge neuroscience, Dr. Farb introduces Sense Foraging, a practice that helps us escape the rigid mental habits that dull our experience of life. Instead of forcing change through willpower, the book reveals how engaging deeply with sensation can enhance resilience, creativity, and well-being. Join us as we unpack the science behind breaking free from stagnation and rediscovering a vibrant connection with the world.

In this episode, we’re joined by Mridula Sathyanarayanan, a third-year undergraduate student at the University of Toronto, majoring in neuroscience, philosophy, and Buddhist Psychology & Mental Health (BPMH). A Laidlaw Scholar, Mridula has been exploring the intersection of contemplative science and public engagement through her innovative project, *The Museum of Meditative Practices*. Her work invites us to rethink how meditation is experienced, studied, and shared, creating an interactive and educational space where diverse meditative traditions come to life. We discuss the inspiration behind her project, the challenges of translating contemplative experiences into public exhibits, and what this means for the future of contemplative science. Tune in for a conversation on the creative ways meditation can be made accessible and immersive—and why this matters for both science and practice.

In this episode, we sit down with Valeria Becattini, a cognitive scientist and philosopher, to explore the paradoxical effects of body-scan meditation on our sense of self. Drawing from her research, Valeria explains how this Theravada Buddhist practice challenges our typical understanding of attention and sensory awareness. Using the predictive processing framework, she reveals how focused attention can lead to the dissolution of bodily boundaries, a phenomenon known as bhaṅga. Together, we delve into the implications of her findings for well-being and discuss how this meditative technique could inform therapeutic approaches for addiction, emotional dysregulation, and self-regulation. Join us for a thought-provoking journey into the intersection of philosophy, neuroscience, and contemplative practices.

How does the brain cultivate optimism, and can psychedelics help people trapped in cycles of depression? In this episode, we’re joined by Beth Fisher, PhD student at M3CS and co-host of Minds Matter. We explore her groundbreaking research using computational models to study how psilocybin influences belief updating and decision-making. Her recent study reveals how psilocybin increases optimistic engagement in rats by reducing loss aversion and modifying memory dynamics. Together, we discuss what this means for treating depression, understanding optimism bias, and unlocking new therapeutic possibilities through psychedelics and cognitive modeling.

In this episode, we sit down with Elli Weisbaum, an Assistant Professor at the University of Toronto in the Buddhism, Psychology, and Mental Health program. Elli shares insights from her extensive experience facilitating mindfulness workshops and retreats across education, healthcare, and business sectors. We discuss her work on applying mindfulness to enhance physician well-being. Elli’s unique background, combining academic research with traditional mindfulness training under Zen Master Thich Nhat Hanh, offers a fresh perspective on mindfulness in contemporary settings.

In this episode, we are joined by Dr. James Cooke, neuroscientist and author of *The Dawn of Mind: How Matter Became Conscious and Alive*. With over a decade of experience studying the brain's role in consciousness, Dr. Cooke shares groundbreaking insights into the nature of the mind, the illusion of the self, and the fundamental relationship between mind and matter. We explore whether consciousness is universal, the philosophical implications of non-separation, and other mysteries of consciousness occurring at the cutting-edge of science.