Twenty-five years ago, Marcelo DeSantis was a programmer writing every line of code by hand, no AI, no autocomplete, his full mental effort poured into the machine. Today he sits on boards, invests in startups, and spends his time helping executives separate what AI can actually do from what it is merely hyped to do. The distance between those two versions of him is the whole story of this episode.
Marcelo came to the US from Argentina and built a career across consumer goods, automotive, and professional services before becoming a senior digital transformation executive at ThoughtWorks. He described his role the way only someone who lived between two worlds could: he was the person who knew the most about technology in a room full of business people, and the most about business in a room full of technologists. He spent a career in that gap, and always focused on one thing, value.
AI is not different. Except in one way that changes everything.
I asked him what makes this technology wave different from the internet, cloud, and mobile waves he has already lived through. His answer was clarifying: they are all the same, except for pace.
Every wave follows the same pattern. A new technology arrives, you pilot it, you fail at some of it, you realize you lack the talent, the governance, the ability to manage it properly. That happened with the internet, with cloud, with everything digital. What makes AI different is speed. He pointed at the last two weeks alone, new models, new legislation, new features shipping every other week, and reminded me that ChatGPT only reached our phones about thirty months ago. There is a clear before and after that moment, and the pace no longer gives anyone time to learn, reflect, and adopt before the next thing lands.
The question every investor should ask about an AI startup
Marcelo’s investing discipline comes down to one question he asks himself before writing a check: is this a business, or is this a feature the large AI labs will ship over a weekend?
If it is the second, it is probably not a good investment. He has watched companies show strong early results and then die when a major lab absorbed their entire value proposition. So what makes a company defensible? His answer was blunt and repeated: data, data, data. Models are becoming a commodity, closed and open source alike are converging and none are far apart. If you do not have a unique dataset that augments the model, anyone with access to the same model gets the same answer you do. Knowledge, he argued, now has a short shelf life. You prompt, you get an answer, and then it is on your judgment to know if it applies. The dataset is the only thing that creates lasting value.
“Do you need money, or do you need a partner?”
Here is the part I keep thinking about, because it is the pattern I have heard across almost every conversation on this show.
As AI turns diligence signals into a commodity, something every investor can access equally, Marcelo believes the firms that win will be the ones built on relationships. Not as a slogan. As the actual asset. He told me that every time a founder approaches him, he asks one question: do you need money, or do you need a partner? If the answer is just money, he sends them to a bank, it is a better, easier deal. If they want someone to open doors, make introductions, and help them grow, that is when he is the right person.
And trust, he emphasized, cannot be manufactured on demand. You do not hold a ceremony and agree to trust each other. It comes organically, through time and interactions, which is exactly why he invests in relationships with an open agenda, trying to understand the person in front of him, contributing where he can, and expecting nothing. Sometimes something comes of it in five years. Sometimes nothing does. Either way, he met the person.
Why the argument still has to be made
I asked why, in 2026, the case for underrepresented fund managers still has to be made explicitly instead of simply being assumed. He named the elephant in the room directly, the current pushback against anything labeled diversity, and then reframed it entirely as a marketer would.
Coming from consumer goods, he sees the Latino community not as an ideological question but as a business one. It is a mosaic, US-born Latinos, immigrants, people from Puerto Rico, Colombia, Venezuela, Uruguay, Brazil, even Spain, and you do not sell the same product the same way to all of them. To capture a segment growing this fast, you need a team that actually understands it. To him, that is not diversity as ideology. It is common business sense. The segment is growing. Do you want to be part of it? Then build the team that can win it.
The advice, and the moat nobody is building yet
His advice for founders was clean: do not fall in love with your idea. AI lets you prototype almost anything in twenty minutes, so get in front of real customers fast, take the feedback seriously, and iterate. At the end of the day it does not matter whether your idea is good or bad. It matters whether customers love it, buy it, and buy it many times over.
And his largest idea, the one most people in venture are not yet paying attention to, was about what actually becomes a company’s moat when AI agents run most of its operations. When agents handle eighty percent of a company’s processes, the only thing left that differs from one company to the next is its corporate DNA. How it makes decisions, what it values, when it takes risk and when it does not. That institutional context, the thing that decides to keep a struggling customer’s account open because you believe in their future even when the numbers say close it, is what no agent can supply on its own. That context is the moat.
We closed, as two people from this part of the world eventually must, on whether Argentina takes the World Cup. He would love it. He is realistic about Spain, Colombia, and France. And he reminded me that in the final against France, Argentina was one French goal away from losing the whole thing. Sometimes you are good. Sometimes you also need to be lucky.
Listen to the full episode of The Corridor with Marcelo DeSantis.
Seguimos. 🇵🇷
Angel León, Coquí Ventures
Coquí Notes is the editorial publication of Coquí Ventures, the diaspora platform connecting Latino founders to community, capital, and the infrastructure that turns ideas into category-defining tech companies.
Get full access to Coquí Notes at coquinotes.substack.com/subscribe