FxTractor, a Snakemake pipeline for extracting COGs, 9-mers, ncRNA families, and amino acid frequencies at scale, trains ML classifiers on 13,554 BacDive isolates that predict salinity, temperature, and oxygen preferences at F1 ≥ 0.88, and SHAP analysis names bacterial large SRP as the temperature discriminator and anti-hemB as the low-salinity discriminator — expanding the ncRNA vocabulary of environmental adaptation. Hosted by Theo & Dr. Mara.

Tracing the roots of The Cell Within the Cell across 6 papers. Hosted by Sofia & Daniel.

The human genome is about two meters (6.6 feet) long, yet it is folded inside a cell nucleus only about 10 micrometers in diameter. To fit into this tiny space, DNA is wrapped around histone proteins to form nucleosomes, which are further organized into chromatin. For decades, chromatin has often been described in two simple forms: euchromatin, which is active, open and accessible, and heterochromatin, which is more compact and repressed. Hosted by Theo & Dr. Mara.

The first Nature Reviews Microbiology synthesis of Starship transposons frames these giant fungal TEs as the only known active eukaryote-to-eukaryote HGT vectors, likely reviewing their captain-gene mechanism, cargo diversity (including virulence effectors), host range, and evolutionary scope — authored from the DOE Joint Genome Institute, the primary fungal comparative genomics infrastructure center. (speculative) Hosted by Sofia & Daniel.

Su9-imported AmAgo Argonaute, programmed by lipofected 18-nt RNA guides against D-loop/R-loop ssDNA, cuts mtDNA copy number ~3-fold in HEK293T. Hosted by Theo & Dr. Mara.

What's happening in AI right now. Hosted by Sofia & Daniel.

Tracing the roots of Plasmids That Go Anywhere across 6 papers. Hosted by Theo & Dr. Mara.

How do related proteins develop different functions? This is the question investigated by a research team involving Kiel University, DESY and the Center for Structural Systems Biology (CSSB). Led by Holger Sondermann, professor at Kiel University and head of the Structural Microbiology group at DESY, the researchers reconstructed the common ancestor of two bacterial enzymes and produced the long-extinct protein in the laboratory. Hosted by Sofia & Daniel.

Tethering the Sso7d DNA-binding domain to T7 RNAP's N-terminus via a ~30-aa flexible linker biases templating toward DNA, cutting dsRNA below detection at 150 mM NaCl. Hosted by Theo & Dr. Mara.

Tracing the roots of Creatures Worth Meeting across 6 papers. Hosted by Theo & Dr. Mara.