The Disruption Lab

What happens when a former underestimated tech founder takes the reins of one of the Midwest’s top entrepreneurial networks? In this raw and powerful episode, Melissa Vincent, Executive Director of Pipeline Entrepreneurs, shares how her lived experiences with bias, exclusion, and early failure became fuel for transforming the startup landscape across Kansas, Missouri, and Nebraska.

Melissa opens up about the hard lessons from her early ventures—including being overlooked as a CEO and navigating a co-founder embezzlement—and how those moments inspired a relentless commitment to inclusion, authenticity, and access. You’ll hear how she doubled Pipeline’s revenue by eliminating membership fees, launched the wildly successful Pathfinder program for untapped entrepreneurs, and built a culture rooted in vulnerability and trust.

We also dive deep into:

Why “serial entrepreneurs” are the economic backbone we’re not talking about

What really creates lasting impact in founder communities (hint: it’s not tech)

The policy shifts and capital mindset the Midwest still needs

And why authenticity—not AI—is the future of leadership

Whether you’re building a company or an ecosystem, this episode is a masterclass in turning purpose into power—and reshaping what startup success really looks like.

In this special live edition of The Disruption Lab recorded at Keystone Sessions, we’re joined by four powerhouse entrepreneurs from around the world—each reshaping the future of work, innovation, and inclusion in their countries.

Meet:

In this episode, they reveal:

The moment they knew this work was their calling

What’s broken in their startup ecosystems—and how they’re fixing it

How they’re rewriting the rules of entrepreneurship in places where the odds are stacked against them

Why visibility, mindset, and access matter more than funding

Whether you’re a startup founder, policy maker, or just someone who believes in the power of ideas, this episode will challenge what you think entrepreneurship looks like—and who gets to lead it.

Tap play and meet the disruptors shaping the future—across borders, against the grain.

Is it finally time for construction to catch up with tech? In this episode of The Disruption Lab, we sit down with Usman Wajid, founder of Block & Mortar, to talk about why construction—one of the world’s largest and slowest-moving industries—is at a critical turning point.

With billions on the line and Boomers retiring fast, Uzi shares how AI isn’t just a buzzword—it’s the bridge between outdated workflows and a faster, smarter future. From the massive knowledge gap to why legacy tools like Procore are leaving developers behind, this episode dives deep into how startups can build real solutions by actually listening to their users.

We also explore how to scale enterprise AI, what most founders get wrong when selling into traditional industries, and why Kansas City might just be the next big startup hub.

If you're curious about:

What construction really needs from AI

How to build tech people will actually use

Why the next billion-dollar startup might not come from Silicon Valley…

You won’t want to miss this.

Ever launched something new and immediately questioned everything? Wondered if the doubts in your head were louder than the market feedback?

In this raw solo episode, we dive deep into the emotional side of entrepreneurship—the stuff nobody puts on a pitch deck. We're talking about fear, uncertainty, self-doubt, and imposter syndrome—not as flaws, but as part of the journey when you're doing something bold and new.

You’ll hear real stories from the front lines of innovation, plus reflections on:

Why fear and doubt might mean you're ahead of your time—not wrong

How imposter syndrome can actually point you in the right direction

Ways to "test" your internal fears like you would a product prototype

Why grace—not just grit—might be your most important founder skill

If you’ve ever wrestled with quiet fears while building loud ideas, this episode is your permission slip to keep going.

Listen now and rethink how you define validation.

In this powerful episode, Dr. Brandy Archie (OTD, OTR/L, CLIPP) —occupational therapist and founder of AskSAMIE and OT Connected—shares the heartbreaking moment that launched her mission to reimagine aging in place. From broken healthcare systems to the hidden realities of home care, Brandy opens up about what most people get wrong about independence, how insurance often fails families, and why the future of care depends on bold entrepreneurs and tech-driven solutions.

You’ll learn:

Why 76% of OTs want to be entrepreneurs—but only 4% actually are

The everyday products and decisions that make or break life at home

How Brandy built not one, but two companies serving caregivers, families, and therapists

The overlooked cost of caregiving—and how it affects everyone

What tech founders without a tech background need to know

If you're a caregiver, healthcare professional, or just someone who wants to live (or help others live) better at home—this episode will change how you see care forever.

Listen now to hear how one simple home visit sparked a national movement.

What do DIY wedding centerpieces, Amazon returns, and climate action have in common? For Send Back founder Shaniqua Jones-Williams—the answer was everything. In this electrifying episode of The Disruption Lab, we sit down with the 2025 Aspen Fellow and rising logistics entrepreneur to unpack how an overstacked return pile in her living room sparked a national reverse logistics platform with a mission.

You’ll hear how Shaniqua:

Went from plus-size shopper frustrations to building a circular economy tech startup

Tackles America’s return crisis while partnering with nonprofits to reduce landfill waste

Navigated early-stage funding, non-technical founder challenges, and startup scaling

Plans to build the largest Black female-owned logistics company in the world

Brings radical transparency, community, and soul to every decision

Whether you've got a return graveyard in your trunk or dreams bigger than your zip code, this episode is packed with insight, inspiration, and straight-up innovation.

Are you building something new and wondering why it feels so overwhelming? In this solo episode of The Disruption Lab, Kevin McGinnis, President and CEO of The Keystone Innovation District, shares the four powerful (and often painful) lessons he’s still learning as a founder, leader, and ecosystem builder.

This isn’t another highlight reel. It’s an honest look at what no one tells you about momentum, clarity, and the emotional toll of innovation. Kevin unpacks why chaos might be a sign you’re on the right path, why the loudest voices aren’t always the most impactful, and how empathy—not hype—is the real secret to lasting success.

Whether you're an entrepreneur, changemaker, or just navigating big decisions, this episode will challenge how you think about progress, leadership, and what it means to truly build something that matters.

In this episode, you'll learn:

Why success and chaos look identical at the start

How to stop mistaking noise for meaningful traction

Why outdated systems hold back real innovation

The surprising power of empathy in business

What it means to lead while still learning

If you’ve ever asked yourself, “Am I doing this right?”—this one’s for you.

Why does it feel like nothing ever changes in local government—even when the ideas are good? In this episode of The Disruption Lab, civic innovation expert Ashley Hand shares what really gets in the way of smarter cities and how to move big ideas forward in a system built to say no.

From leading smart city projects in LA and Kansas City to launching public-private partnerships and opening an elementary school from scratch, Ashley has seen it all. She dives into why bureaucracy isn’t always the enemy, how to work with the system instead of against it, and the biggest myths people believe about tech, transportation, and public service.

You’ll learn:

Why most smart city tech fails (and what to do instead)

How to actually pitch innovation to City Hall (and who to call first)

The one thing cities should never deploy without a clear policy

What every startup should know before approaching government

How public service can be joyful—even now

Whether you’re a policymaker, founder, or just frustrated by the slow pace of change, this episode offers a refreshing, practical, and hopeful take on building better cities from the inside out.

Most people have never heard of refrigerants—but they’re one of the most dangerous climate pollutants on Earth. In this live episode of The Disruption Lab, we sit down with Kalin Baca, PhD scientist turned climate tech founder of Icorium, who’s on a mission to stop these super pollutants from quietly warming the planet.

Kalin breaks down how refrigerants—used in everything from air conditioners to data centers—have global warming potentials thousands of times higher than carbon dioxide… and why almost no one is talking about it. She also shares how her startup is disrupting the $20B+ refrigerant industry by building separation tech that could eliminate the need for incineration and enable a true circular economy for cooling.

We explore:

The science behind refrigerants and why they matter more than ever

How Kalin went from lab researcher to founder through NSF’s iCorps

What it takes to launch a deep tech company in a traditionally stagnant industry

Why refrigerant demand is rising globally—and why this matters for the future of climate

How Icorium’s innovation could transform the way we manage industrial emissions

If you care about climate innovation, deep tech startups, or how to take hard science to market—this is an episode you don’t want to miss.

What happens when you follow all the rules, invest $350,000 of your own money, and still end up broke? Dr. Donnetta Watson—known as The Launch Strategist—did exactly that. In this powerful live episode of The Disruption Lab, she opens up about the moment that changed her life, the cultural myths holding Black entrepreneurs back, and why mindset—not money—is the real foundation for wealth.

You’ll learn the hard truths most business schools don’t teach:

This isn’t just another motivational story—it’s a masterclass on sustainability, systems, and financial empowerment. If you’re an entrepreneur, aspiring founder, or ecosystem builder, this episode is a must-listen.

Plus, hear how Dr. Watson is building a 25,000 sq ft center to incubate real, fundable Black businesses—and why place and visibility matter more than ever.