Yale Immunobiology Professor and Scientific Founder of Simcha Therapeutics and Seranova Bio, Dr. Aaron Ring, discusses his journey starting a lab spinning out companies building therapeutics for patients right out of his MD/PhD program. We close out the final episode of the season with a conversation around generating leading science with translational potential, spinning out biotech companies, finding a management team, and the relationship between investors and scientific founders in biotech.

Internist, Professor and Stanford Health Care Chief Medical Officer Dr. Niraj Sehgal joins for the first in-person conversation since the pandemic started on what it means to be Chief Medical Officer of an Academic Medical System, his journey becoming the Chief Quality Officer of the UCSF Health System and Chief Medical Officer of Stanford Health Care, and the role of hospital administration in tackling the big challenges facing the US healthcare system. Join for an engaging conversation around hospital leadership, healthcare reform, and disruption risks for provider systems from a career educator and healthcare leader.

Explore differences between a health system CMO, a biotech CMO, and a health IT CMO through other TDIO episodes!

Learn more about the biotech CMO path here: https://anchor.fm/tdio/episodes/S1E10-Breaking-into-Biotech---Angela-Shen-etocs0

Learn more about the health IT CMO path here: https://anchor.fm/tdio/episodes/S2E03-Disrupting-Mental-Health---Connie-Chen-e15ksf0

Can systemic social challenges in healthcare be tackled by a for-profit business? Can entrepreneurship be a force to do well and good in healthcare?

In this episode, we go into the remarkable career journey of Dr. Gary Gottlieb, who went from his practice as a Geriatric Psychiatrist to become a national healthcare leader as the former CEO of the Partners Healthcare System, the former President of Brigham and Women's Hospital, the former CEO of Partners in Health, and now an Executive Partner at Flare Capital serving on the boards of prominent healthcare startups.

Is formal business training necessary to build an impactful company as a physician? Is it possible to start a successful company during clinical training?

Medable CEO and Dermatologist Dr. Michelle Longmire discusses her journey defying conformity and stereotypes to become one of healthcare's pre-eminent physician leaders building a disruptive $2B startup transforming the way clinical trials are conducted. Join for a broad-ranging conversation on being an entrepreneurial outsider, starting a company during clinical training, decentralized clinical trials, SPACs and the commercialization of personalized medicines.

What does it mean to be a content creator as a physician? 

KevinMD founder and primary care physician Dr. Kevin Pho discusses his career as a physician social media influencer and editor of the Medpage blog KevinMD. Join for a conversation around how "the definition of what a doctor does is changing" and counteracting burnout in clinical practice.

How do you innovate as an entrepreneur in medical education?

What happens when you disrupt the healthcare workforce industry while it is being disrupted by a global pandemic?

Can we create incentives to make medicine do the right thing? Is healthcare a public good or a commodity?

Join for a conversation around the business of medicine with Dr. Elisabeth Rosenthal, Kaiser Health News Editor-in-Chief, NY Times Contributor and author of "An American Sickness: How Healthcare Became Big Business and How You Can Take It Back". Learn about Elisabeth's journey toward becoming an author and journalist, and her recommendations for what can be done to bring reform to the healthcare system.

Is Medicare Advantage delivering on its promise of higher quality, lower cost care or has it become an overlooked vehicle for arbitrage with tax payers stuck with the bill?

Join also for a discussion on what it was like to be CMS Administrator, the value of an MPP in medicine, as well as the "growth that happens at the intersections" of disciplines that can lead to career development.

Read Dr. Berwick's recent publication with former Trinity Health CEO and first CMMI Director Dr. Richard Gilfillan in Health Affairs here: https://www.healthaffairs.org/do/10.1377/hblog20210927.6239/full/.