The Duration Wellness Show

Building a robust Preventative Wellness Foundation is the key to maintaining peak biological performance as you age. Krista and Dr. Anna Marie design actionable, science-backed strategies to help you prioritize your long-term vitality before health challenges arise. In this raw conversation, they share why they founded Duration Wellness alongside their husbands, Lantz and Montana. You'll learn why treating your body as your most valuable asset ensures your healthspan matches your lifespan. They also reveal details about their upcoming science-backed sleep aid, designed to optimize your recovery and daily systemic performance.

Achieving peak cognitive and physical performance starts with optimizing sleep quality to repair systemic decline. Dr. Anna Marie explains how proper rest acts as a critical biological reset for your brain and metabolism. High performers often sacrifice rest to meet demanding schedules, unaware that chronic sleep deprivation directly compromises insulin sensitivity and immune function. We break down the clinical mechanisms of the glymphatic waste clearance system and how nighttime routines impact long-term cardiovascular health. You'll learn actionable, science-backed strategies for sleep hygiene, gut microbiome optimization, and targeted supplementation to protect your healthspan.

Prioritizing your daily habits is the single most effective strategy for dementia prevention. In this episode, host Dr. Anna Marie and Dr. Karen McCarthy break down the critical sleep and gut connection required to keep your brain healthy. You'll learn how different sleep stages clear out toxic proteins and how a simple mental trick can shut off your racing mind. They also discuss how gut health and fiber consumption protect your blood-brain barrier from harmful inflammation. Finally, discover the latest breakthroughs in early detection biomarkers that can identify risks decades before symptoms appear.

You don't have to accept cognitive decline as an inevitable part of aging, even if you have a genetic predisposition. Host Dr. Anna Marie and internal medicine specialist Dr. Karen McCarthy share actionable protocols for proactive Dementia Prevention. They discuss how targeted lifestyle changes can modify genetic risks, balance your gut microbiome, and optimize cellular clearance systems. You'll learn the science behind intermittent fasting, heavy metal detoxification, and the critical role of sleep architecture. This discussion gives high-performing professionals the diagnostic tools and daily habits needed to preserve their cognitive edge for decades.

Your brain health isn't entirely determined by your genetics, and you can take active control of your cognitive future. We look at the clinical science behind Dementia Prevention with guest Dr. Karen McCarthy and host Dr.Anna Marie. You'll learn how simple changes to your diet, exercise routine, and sleep habits shield your brain from cognitive decline. We break down the specific nutrients and supplements that support long-term memory and neural power. Don't wait for symptoms to appear before you start prioritizing your neurological healthspan.

We all face sudden health choices that require swift, informed decisions. In this conversation, host Dr. Anna Marie sits down with board-certified emergency medicine physician Dr. Eric Edgerton to demystify how you can navigate emergency medical care with confidence. They break down the critical differences between a standard emergency department, a freestanding facility, and urgent care. You'll discover when it's vital to bypass driving and call emergency services, especially if you're taking specific long-term medications. Dr. Eric Edgerton also explains how establishing a strong partnership with a primary care physician serves as your best defense. Learn to recognize true physical warning signs so you can protect your longevity and secure immediate support when it matters most.

Many people use the terms Microplastics and Endocrine Disruptors synonymously, but they're actually distinct threats to your daily wellness. Dr. Anna Marie McCarthy joins us to break down how these synthetic particles and chemicals infiltrate our bodies through water, food, and even the air we breathe. We discuss the shocking clinical data showing their accumulation in human organs, including the cardiovascular system and the brain. You'll learn the difference between short-half-life chemicals that leave your system quickly and persistent forever chemicals that stay for decades. We outline practical, medically backed steps to reduce your daily exposure and safeguard your cellular health. You don't have to live under a rock to protect your family from these invisible environmental stressors.

Are you confused by all the conflicting nutrition advice for your heart? Discover why a heart healthy diet remains the gold standard for reducing cardiovascular risk, according to expert cardiologist Dr. Khadeeja Esmail. She joins us to break down the science behind the Mediterranean diet, explaining exactly how specific food choices can slow plaque progression and improve your long-term heart health. We tackle the myths surrounding low-carb trends, the truth about beef tallow, and simple, sustainable changes you can start today. Whether you’re looking to prevent heart disease or simply want to eat better, Dr. Khadeeja Esmail from UF Health Jacksonville offers the expert clarity you need to make informed decisions.

What actually happens to your brain when you are "put under"? And why is that strict "no eating" rule before surgery really a matter of life and death? In this episode, we sit down with seasoned anesthesiologist Dr. Dennis McCarthy to pull back the curtain on one of the most critical—and often misunderstood—roles in modern medicine.

From deconstructing the differences between general anesthesia, twilight sedation, and nerve blocks, to the vital importance of being honest about alcohol, supplements, and medication, Dr. McCarthy guides us through everything you need to know to feel informed and safe. Whether you are prepping for a procedure or just curious about the science behind sleep, this deep dive into patient safety, anesthesia technology, and pre-op preparation will help calm your nerves and empower your next medical conversation.

Struggling to lose weight often feels like a losing battle, but the latest medical research suggests the challenge is often biological, not just a matter of willpower. For those managing obesity, metabolic adaptation—where the body actively works to regain lost weight—can make sustainable change feel impossible.

In this deep dive, we sit down with board-certified cardiologist Dr. Pamela Rama to pull back the curtain on the science behind modern weight loss medicines. From explaining how GLP-1 and GIP receptor agonists work to signal satiety and extend the half-life of natural hormones, to navigating insurance coverage and managing side effects, Dr. Rama provides a comprehensive look at the treatment landscape. She explains why viewing obesity as a chronic medical condition—rather than a character flaw—is the critical first step toward reclaiming health. Discover how these interventions are doing more than just helping patients lose weight; they are reducing inflammation, protecting heart health, and offering a legitimate path to long-term vitality.