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The Egg Factor
The Egg Factor episodes
- Breaking down SART outcomes
Success rates are one of the most common ways fertility clinics are compared—but what do the numbers actually mean?
In this episode of The Egg Factor, CHR’s Medical Director Dr. Norbert Gleicher and Associate Medical Director Dr. David Barad break down the latest SART (Society for Assisted Reproductive Technology) outcome data.
Together, they unpack:
- How SART collects and reports IVF outcomes across U.S. clinics
- Why success rates can be misleading—especially for patients over 40 or those with diminished ovarian reserve
- The unintended consequences of “competing by numbers,” including why some clinics turn away challenging cases to keep their stats high
- CHR’s unique approach, and why they accept patients other clinics often won’t
At CHR, we believe patients deserve more than statistics—they deserve honesty, context, and individualized care. Tune in as Dr. Gleicher and Dr. Barad explain how to read between the lines of success rate data, and what really matters when choosing a fertility clinic.
Brought to you by the Center for Human Reproduction (CHR) on the Upper East Side of New York City. With over 40 years of experience and a history of innovation, CHR has been at the forefront of fertility care since the beginning.
Our founder, Dr. Norbert Gleicher, reported the first successful transvaginal egg retrieval in human history, helping to shape the future of IVF as we know it today. CHR is known for tackling some of the most challenging fertility cases—especially women over 40 and those with diminished ovarian reserve—by offering highly individualized, evidence-based care when others often turn patients away.
Our team has published more than 450 peer-reviewed research papers advancing reproductive medicine, reflecting our deep commitment not only to patient care but to the science that drives better outcomes. At CHR, you're never just a number. You're part of a community focused on giving you the personalized support, science, and hope you deserve.
Website: www.thechr.com
Facebook: https://www.facebook.com/chrnewyork
Instagram: https://www.instagram.com/chrnewyork/
Linkedin: https://www.linkedin.com/company/centerforhumanreproduction/
Pinterest: https://www.pinterest.com/CenterforHumanReproduction/
TikTok: https://www.tiktok.com/@chrnewyork
15 min - The Hormone Reset: Understanding the Endocrine and Immune Shifts of Perimenopause and Their Fertility Implications
As fertility declines with age, it's not just about egg quantity—it's about the entire hormonal and immune environment surrounding the ovaries. In this episode of The Egg Factor, CHR’s physicians break down the nuanced changes that happen in the late 30s and 40s, including shifts in estrogen, testosterone, and DHEA levels—and how these changes impact ovarian function and embryo quality.
Listen now on Spotify, Apple Podcasts, or wherever you get your podcasts.
Brought to you by the Center for Human Reproduction (CHR) on the Upper East Side of New York City. With over 40 years of experience and a history of innovation, CHR has been at the forefront of fertility care since the beginning.
Our founder, Dr. Norbert Gleicher, reported the first successful transvaginal egg retrieval in human history, helping to shape the future of IVF as we know it today. CHR is known for tackling some of the most challenging fertility cases—especially women over 40 and those with diminished ovarian reserve—by offering highly individualized, evidence-based care when others often turn patients away.
Our team has published more than 450 peer-reviewed research papers advancing reproductive medicine, reflecting our deep commitment not only to patient care but to the science that drives better outcomes. At CHR, you're never just a number. You're part of a community focused on giving you the personalized support, science, and hope you deserve.
Website: www.thechr.com
Facebook: https://www.facebook.com/chrnewyork
Instagram: https://www.instagram.com/chrnewyork/
Linkedin: https://www.linkedin.com/company/centerforhumanreproduction/
Pinterest: https://www.pinterest.com/CenterforHumanReproduction/
TikTok: https://www.tiktok.com/@chrnewyork
18 min - Lean PCOS & Low Androgens: The Overlooked Diagnosis Sabotaging Fertility Over 35
Not all PCOS is created equal. In this solo episode of The Egg Factor, CHR’s Medical Director Dr. Norbert Gleicher dives into one of the most misunderstood—and frequently missed—diagnoses in reproductive medicine: lean PCOS with low androgens, also known as D-phenotype PCOS.
Often overlooked because these patients don’t fit the “typical” PCOS profile, women with D-phenotype are usually thin, have regular periods, and no obvious signs of excess androgens. But as they age—especially after 35—their androgen levels decline dramatically, quietly sabotaging their fertility. Many are prescribed inositol supplements that could actually make things worse.
Dr. Gleicher unpacks the science behind this phenotype, explains why standard protocols fall short, and offers guidance on how to recognize and treat this subtle but significant hormonal imbalance.
If you’ve been diagnosed with PCOS but don’t quite relate to the usual symptoms—or you’ve been told everything looks “normal” despite ongoing fertility struggles—this episode is a must-listen.
Available now on Spotify, Apple Podcasts, and all major podcast platforms.
Brought to you by the Center for Human Reproduction (CHR) on the Upper East Side of New York City. With over 40 years of experience and a history of innovation, CHR has been at the forefront of fertility care since the beginning.
Our founder, Dr. Norbert Gleicher, reported the first successful transvaginal egg retrieval in human history, helping to shape the future of IVF as we know it today. CHR is known for tackling some of the most challenging fertility cases—especially women over 40 and those with diminished ovarian reserve—by offering highly individualized, evidence-based care when others often turn patients away.
Our team has published more than 450 peer-reviewed research papers advancing reproductive medicine, reflecting our deep commitment not only to patient care but to the science that drives better outcomes. At CHR, you're never just a number. You're part of a community focused on giving you the personalized support, science, and hope you deserve.
Website: www.thechr.com
Facebook: https://www.facebook.com/chrnewyork
Instagram: https://www.instagram.com/chrnewyork/
Linkedin: https://www.linkedin.com/company/centerforhumanreproduction/
Pinterest: https://www.pinterest.com/CenterforHumanReproduction/
TikTok: https://www.tiktok.com/@chrnewyork
16 min - Nutrition vs. Medication: Can Diet Alone Influence IVF Success in Women Over 40?
In this solo episode of The Egg Factor, Dr. Norbert Gleicher, Medical Director of CHR, unpacks the complex relationship between nutrition, inflammation, insulin resistance, and reproductive outcomes in women over 40. Drawing on decades of clinical and research experience, Dr. Gleicher dives into how specific micronutrients and metabolic factors influence egg quality, implantation, and miscarriage risk.
Our founder, Dr. Norbert Gleicher, reported the first successful transvaginal egg retrieval in human history, helping to shape the future of IVF as we know it today. CHR is known for tackling some of the most challenging fertility cases—especially women over 40 and those with diminished ovarian reserve—by offering highly individualized, evidence-based care when others often turn patients away.
Our team has published more than 450 peer-reviewed research papers advancing reproductive medicine, reflecting our deep commitment not only to patient care but to the science that drives better outcomes. At CHR, you're never just a number. You're part of a community focused on giving you the personalized support, science, and hope you deserve.
Website: www.thechr.com
Facebook: https://www.facebook.com/chrnewyork
Instagram: https://www.instagram.com/chrnewyork/
Linkedin: https://www.linkedin.com/company/centerforhumanreproduction/
Pinterest: https://www.pinterest.com/CenterforHumanReproduction/
TikTok: https://www.tiktok.com/@chrnewyork
14 min - The Fertility Cliff Reconsidered: What the Data Really Shows for Women 40 and Over
We’ve all heard it: after 40, your chances of conceiving with your own eggs plummet. But is the data behind the so-called "fertility cliff" as clear-cut as it seems?
In this episode of The Egg Factor, CHR's Dr. Norbert Gleicher unpacks research, clinical experience, and patient outcomes to challenge the mainstream narrative. He explores how fertility statistics have been widely misinterpreted, why donor eggs are often recommended too quickly, and what ovarian potential really looks like in women over 40.
If you’ve been told your only option is egg donation—or you’re wondering whether age alone should determine your treatment path—this conversation is for you.
Listen now on Spotify, Apple Podcasts, or wherever you get your podcasts.
Brought to you by the Center for Human Reproduction (CHR) on the Upper East Side of New York City. With over 40 years of experience and a history of innovation, CHR has been at the forefront of fertility care since the beginning.
Our founder, Dr. Norbert Gleicher, reported the first successful transvaginal egg retrieval in human history, helping to shape the future of IVF as we know it today. CHR is known for tackling some of the most challenging fertility cases—especially women over 40 and those with diminished ovarian reserve—by offering highly individualized, evidence-based care when others often turn patients away.
Our team has published more than 450 peer-reviewed research papers advancing reproductive medicine, reflecting our deep commitment not only to patient care but to the science that drives better outcomes. At CHR, you're never just a number. You're part of a community focused on giving you the personalized support, science, and hope you deserve.
Website: www.thechr.com
Facebook: https://www.facebook.com/chrnewyork
Instagram: https://www.instagram.com/chrnewyork/
Linkedin: https://www.linkedin.com/company/centerforhumanreproduction/
Pinterest: https://www.pinterest.com/CenterforHumanReproduction/
TikTok: https://www.tiktok.com/@chrnewyork
12 min - What Does It Really Mean When Ovaries Age?
We often hear about the biological clock—but what does “ovarian aging” really mean? In this episode of The Egg Factor, Dr. Norbert Gleicher and Dr. David Barad explain the science behind ovarian aging, how it differs from chronological age, and what it means for fertility—especially for women in their late 30s, 40s, or those diagnosed with low ovarian reserve.
Brought to you by the Center for Human Reproduction (CHR) on the Upper East Side of New York City. With over 40 years of experience and a history of innovation, CHR has been at the forefront of fertility care since the beginning.
Our founder, Dr. Norbert Gleicher, reported the first successful transvaginal egg retrieval in human history, helping to shape the future of IVF as we know it today. CHR is known for tackling some of the most challenging fertility cases—especially women over 40 and those with diminished ovarian reserve—by offering highly individualized, evidence-based care when others often turn patients away.
Our team has published more than 450 peer-reviewed research papers advancing reproductive medicine, reflecting our deep commitment not only to patient care but to the science that drives better outcomes. At CHR, you're never just a number. You're part of a community focused on giving you the personalized support, science, and hope you deserve.
Website: www.thechr.com
Facebook: https://www.facebook.com/chrnewyork
Instagram: https://www.instagram.com/chrnewyork/
Linkedin: https://www.linkedin.com/company/centerforhumanreproduction/
Pinterest: https://www.pinterest.com/CenterforHumanReproduction/
TikTok: https://www.tiktok.com/@chrnewyork
17 min - Inside the Fertility Lab: What Patients Need to Know About Embryos, Grading, & Genetic Testing
What really happens behind the microscope?
In this episode of The Egg Factor, Dr. Norbert Gleicher, Dr. David Barad, and world-renowned embryologist Dr. David Albertini take you inside the fertility lab to demystify some of the most misunderstood parts of the IVF process.
They break down:
-How embryos are graded—and what those grades actually mean
-What exactly about morphology is important
-The truth about PGT-A (and whether it improves your chances)
-How many times can you freeze a human embryo?
Why CHR often works with embryos other clinics would discard
Whether you’re preparing for your first cycle or navigating a complicated fertility journey, this conversation will give you the tools to better understand your options—and advocate for the care you deserve.Brought to you by the Center for Human Reproduction (CHR) on the Upper East Side of New York City. With over 40 years of experience and a history of innovation, CHR has been at the forefront of fertility care since the beginning.
Our founder, Dr. Norbert Gleicher, reported the first successful transvaginal egg retrieval in human history, helping to shape the future of IVF as we know it today. CHR is known for tackling some of the most challenging fertility cases—especially women over 40 and those with diminished ovarian reserve—by offering highly individualized, evidence-based care when others often turn patients away.
Our team has published more than 450 peer-reviewed research papers advancing reproductive medicine, reflecting our deep commitment not only to patient care but to the science that drives better outcomes. At CHR, you're never just a number. You're part of a community focused on giving you the personalized support, science, and hope you deserve.
Website: www.thechr.com
Facebook: https://www.facebook.com/chrnewyork
Instagram: https://www.instagram.com/chrnewyork/
Linkedin: https://www.linkedin.com/company/centerforhumanreproduction/
Pinterest: https://www.pinterest.com/CenterforHumanReproduction/
TikTok: https://www.tiktok.com/@chrnewyork
22 min - The Three Person Embryo: Science, Ethics & the FDA Ban
In this episode of The Egg Factor, Dr. Norbert Gleicher, Dr. David Barad, and Dr. David Albertini unpack one of the most controversial topics in reproductive medicine today: Three-Person IVF—also known as mitochondrial replacement therapy.
Together, they break down:
- What “three-parent embryos” actually are
- The science behind mitochondrial transfer
- Why this technique is currently banned by the FDA
- And the serious ethical and biological concerns it raises
While headlines might portray it as a breakthrough, CHR’s team sees it differently. Tune in for a grounded, science-based conversation about why this experimental method isn't the solution it's being marketed to be—and what real innovation in fertility care should look like.
Brought to you by the Center for Human Reproduction (CHR) on the Upper East Side of New York City. With over 40 years of experience and a history of innovation, CHR has been at the forefront of fertility care since the beginning.
Our founder, Dr. Norbert Gleicher, reported the first successful transvaginal egg retrieval in human history, helping to shape the future of IVF as we know it today. CHR is known for tackling some of the most challenging fertility cases—especially women over 40 and those with diminished ovarian reserve—by offering highly individualized, evidence-based care when others often turn patients away.
Our team has published more than 450 peer-reviewed research papers advancing reproductive medicine, reflecting our deep commitment not only to patient care but to the science that drives better outcomes.
At CHR, you're never just a number. You're part of a community focused on giving you the personalized support, science, and hope you deserve.
Website: www.thechr.com
Facebook: https://www.facebook.com/chrnewyork
Instagram: https://www.instagram.com/chrnewyork/
Linkedin: https://www.linkedin.com/company/centerforhumanreproduction/
Pinterest: https://www.pinterest.com/CenterforHumanReproduction/
TikTok: https://www.tiktok.com/@chrnewyork15 min - Fertility Q&A: Day 3 FETs & Chromosomal Concerns Over 40 with Dr. David Barad and Dr. Norbert Gleicher
In this listener-driven Q&A episode of The Egg Factor, CHR’s Dr. Norbert Gleicher and Dr. David Barad answer two critical questions from our patient community. First up: If you're doing a Day 3 frozen embryo transfer (FET) and had no choice—should you opt for a medicated or modified natural cycle? Then, the doctors tackle a question that weighs heavily on many: What are the most common chromosomal abnormalities seen in women 40 and older, and how do they impact fertility treatment?
Known for their candor and decades of clinical experience, Dr. Gleicher and Dr. Barad break down the science behind these decisions and offer guidance for navigating the complex path to parenthood later in life.
Brought to you by the Center for Human Reproduction (CHR) on the Upper East Side of New York City. With over 40 years of experience and a history of innovation, CHR has been at the forefront of fertility care since the beginning.
Our founder, Dr. Norbert Gleicher, reported the first successful transvaginal egg retrieval in human history, helping to shape the future of IVF as we know it today. CHR is known for tackling some of the most challenging fertility cases—especially women over 40 and those with diminished ovarian reserve—by offering highly individualized, evidence-based care when others often turn patients away.
Our team has published more than 450 peer-reviewed research papers advancing reproductive medicine, reflecting our deep commitment not only to patient care but to the science that drives better outcomes. At CHR, you're never just a number. You're part of a community focused on giving you the personalized support, science, and hope you deserve.
Website: www.thechr.com
Facebook: https://www.facebook.com/chrnewyork
Instagram: https://www.instagram.com/chrnewyork/
Linkedin: https://www.linkedin.com/company/centerforhumanreproduction/
Pinterest: https://www.pinterest.com/CenterforHumanReproduction/
TikTok: https://www.tiktok.com/@chrnewyork
15 min - Fertility and the Law: What Legislation Really Means for IVF
With headlines swirling about legal threats to IVF and fertility treatment, many patients are left feeling anxious and uncertain. In this episode of The Egg Factor, Dr. Norbert Gleicher and Dr. David Barad break down the recent legislative developments—and what they actually mean for fertility care in the U.S.
Brought to you by the Center for Human Reproduction (CHR) on the Upper East Side of New York City. With over 40 years of experience and a history of innovation, CHR has been at the forefront of fertility care since the beginning.
Our founder, Dr. Norbert Gleicher, performed the first successful transvaginal egg retrieval in human history, helping to shape the future of IVF as we know it today. CHR is known for tackling some of the most challenging fertility cases—especially women over 40 and those with diminished ovarian reserve—by offering highly individualized, evidence-based care when others often turn patients away.
Our team has published more than 450 peer-reviewed research papers advancing reproductive medicine, reflecting our deep commitment not only to patient care but to the science that drives better outcomes. At CHR, you're never just a number. You're part of a community focused on giving you the personalized support, science, and hope you deserve.
Website: www.thechr.com
Facebook: https://www.facebook.com/chrnewyork
Instagram: https://www.instagram.com/chrnewyork/
Linkedin: https://www.linkedin.com/company/centerforhumanreproduction/
Pinterest: https://www.pinterest.com/CenterforHumanReproduction/
TikTok: https://www.tiktok.com/@chrnewyork
13 min
About The Egg Factor
From the publisher's feed
Welcome to The Egg Factor, a podcast dedicated to exploring the latest research and developments in the field of fertility. Hosted by Dr. Norbert Gleicher, a world-renowned fertility specialist…
with over 40 years of experience, this podcast provides expert insights and advice for anyone interested in improving their chances of conceiving.
From the latest breakthroughs in reproductive technology to the best ways to optimize your fertility naturally, Dr. Gleicher and his team of experts cover it all. With a focus on evidence-based research and personalized care, The Egg Factor offers a unique perspective on fertility that you won't find anywhere else.
Whether you're just starting your fertility journey or you're looking for advanced solutions, The Egg Factor is the podcast for you. So tune in to stay up-to-date with the latest developments in the fertility industry and get expert advice on how to maximize your chances of conception.
From the latest breakthroughs in reproductive technology to the best ways to optimize your fertility naturally, Dr. Gleicher and his team of experts cover it all. With a focus on evidence-based research and personalized care, The Egg Factor offers a unique perspective on fertility that you won't find anywhere else.
Whether you're just starting your fertility journey or you're looking for advanced solutions, The Egg Factor is the podcast for you. So tune in to stay up-to-date with the latest developments in the fertility industry and get expert advice on how to maximize your chances of conception.