Dr. Michael Harrison didn't set out to invent a field of medicine — he set out to save one baby. In this episode of The Fetal Frontline, host Kris Rimbos sits down with the surgeon widely known as the Father of Fetal Surgery for a wide-ranging conversation about how operating on a patient before birth went from unthinkable to standard of care.
Harrison traces the whole arc: the newborn with a diaphragmatic hernia whose death revealed the real problem began before birth; choosing UCSF — an "up-and-coming" school unbound by tradition, where a radical idea could actually be pursued; answering skeptics with roughly 1,500 fetal-lamb operations instead of argument; and the "marriage of disciplines" — surgery, obstetrics, perinatology, neonatology — that turned an experiment into a specialty. He reflects on the ethics of caring for two patients at once, the mind-bending first open fetal surgeries, and Michael Skinner, the first baby to survive one, whose family named him after his surgeon. He explains how spina bifida reframed the goal from saving a life to protecting a way of life, how necessity drove the device work of his "D-VICE squad," and what Yale crew taught him about endurance. Finally, he looks ahead — to genetics, metabolic disease, and AI — and shares the legacy he hopes endures: not the answers, but the constant questioning. Along the way, he names the achievement he's proudest of: his family.
In this episode:
- The single case that launched a field — and the insight that the problem was pulmonary, before birth
- Why it had to be UCSF, the "Wild West" where a radical idea could be tried
- Answering the skeptics with data: ~1,500 fetal-lamb operations
- A marriage of disciplines, NAFTNet & IFMSS, and the ethics of the unborn patient
- Michael Skinner, spina bifida, and the devices necessity demanded
- Mentoring the next generation, the future of genetics & AI, and a life kept well-ordered
Chapters:
- 0:00 — Welcome: the Father of Fetal Surgery
- 1:27 — A doctor like his father
- 2:41 — The case that changed everything
- 5:37 — UCSF and the "Wild West"
- 7:12 — Answering the skeptics
- 9:25 — A marriage of disciplines
- 11:19 — Building a global network (NAFTNet & IFMSS)
- 12:37 — Ethics of the unborn patient
- 13:33 — Innovation and patient safety
- 16:27 — Inside the first fetal surgery
- 17:40 — Michael Skinner: living proof
- 18:37 — Spina bifida and quality of life
- 19:46 — Necessity drives innovation (the D-VICE squad)
- 22:55 — Rowing, grit, and endurance
- 24:30 — Mentoring the next generation
- 27:41 — The future: genetics & AI
- 29:26 — Legacy: keep questioning
- 31:12 — Family, and a life well-ordered
Guest: Dr. Michael Harrison, MD — pediatric and fetal surgeon; founder of the UCSF Fetal Treatment Center, the world's first.
Host: Kris Rimbos — host of The Fetal Frontline and an FTNN board member.
Learn more about the Fetal Therapy Nurse Network at fetaltherapynursenetwork.org, and subscribe to The Fetal Frontline wherever you listen.