
Sign up to save your podcasts
Or


The results of human studies assessing the efficacy of lycopene on insulin-like growth factor 1 (IGF-1) levels are inconsistent. Thus, we performed a systematic review and meta-analysis to examine the effects of lycopene supplementation on serum IGF-1 levels and cardiovascular disease.
The literature published up to January 2020 was searched using the electronic databases Scopus, PubMed/Medline, Web of Science, Embase and Google Scholar.
Seven qualified trials were included in the current meta-analysis. IGF-1 levels were non-significantly decreased in lycopene group compared to the control (WMD: −6.74 ng/mL, 95 % CI: −23.01 to 9.52, p = 0.42; I2 = 94.3 %). Subgroup analysis revealed a significantly decrease in IGF-1 levels upon lycopene supplementation at doses ≥15 mg/d (WMD: −6.40 ng/mL), intervention period 15 mg/d, for
By Progressive Radio Network4.6
462462 ratings
The results of human studies assessing the efficacy of lycopene on insulin-like growth factor 1 (IGF-1) levels are inconsistent. Thus, we performed a systematic review and meta-analysis to examine the effects of lycopene supplementation on serum IGF-1 levels and cardiovascular disease.
The literature published up to January 2020 was searched using the electronic databases Scopus, PubMed/Medline, Web of Science, Embase and Google Scholar.
Seven qualified trials were included in the current meta-analysis. IGF-1 levels were non-significantly decreased in lycopene group compared to the control (WMD: −6.74 ng/mL, 95 % CI: −23.01 to 9.52, p = 0.42; I2 = 94.3 %). Subgroup analysis revealed a significantly decrease in IGF-1 levels upon lycopene supplementation at doses ≥15 mg/d (WMD: −6.40 ng/mL), intervention period 15 mg/d, for

12,091 Listeners

3,993 Listeners

567 Listeners

2,346 Listeners

120 Listeners

496 Listeners

16,791 Listeners

1,374 Listeners

696 Listeners

920 Listeners

20 Listeners

2,486 Listeners

237 Listeners

550 Listeners

497 Listeners