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Onion extracts lower blood pressure for hypertensives: study

University of Bonn (Germany), September 7, 2022

Taking onion skin-derived food supplements of the flavonol quercetin can lower blood pressure for people with hypertension, according to a new study published in the British Journal of Nutrition.

Researchers from the University of Bonn in Germany conducted a double-blind study on 68 overweight or obese volunteers with pre-hypertension or stage 1 hypertension, giving them either a quercetin-rich onion skin extract supplement or a placebo for six weeks.

While the subjects who were not classed as having high blood pressure did not show significant changes, those with high blood pressure saw positive results.

“Supplementation with 162 mg/d quercetin from onion skin extract lowers [ambulatory blood pressure] in patients with hypertension, suggesting a cardioprotective effect of quercetin. The mechanisms responsible for the [blood pressure]-lowering effect remain unclear,” wrote the study’s authors.

Quercetin is an antioxidant commonly found in plants, including onions, kale, apple skins, berries, citrus fruits and tea.

Participants with hypertension saw their systolic blood pressure fall an average of 3.6 mmHg, which the authors suggested “would be clinically meaningful when considered at the population level, particularly in view of the large population of people with pre-hypertension and stage I hypertension”.

The dose of 162 mg per day of quercetin-rich onion skin extract, in the form of three 54 mg capsules, was identified as being approximately 10 to 15 times the normal daily quercetin intake for people in the European Union. The study excluded people who consumed high levels of quercetin in their normal diets.

Older adults with regular activity routines are happier and do better on cognitive tests, study findsUniversity of Pittsburgh, September 12, 2022

Older adults who consistently get up early and remain active throughout the day are happier and perform better on cognitive tests than those with irregular activity patterns, according to a new study led by University of Pittsburgh researchers.

The findings, published online in JAMA Psychiatry, suggest that patterns of activity—not just activity intensity—are important for healthy aging and mental health.

“There’s something about getting going early, staying active all day and following the same routine each day that seems to be protecting older adults,” said lead author Stephen Smagula, Ph.D., assistant professor of psychiatry and epidemiology at Pitt. “What’s exciting about these findings is that activity patterns are under voluntary control, which means that making intentional changes to one’s daily routine could improve health and wellness.”

To learn more about daily activity patterns in U.S.-based older adults and identify links with mental health and cognition, Smagula and his team recruited 1,800 senior citizens aged over 65. Participants wore accelerometers—movement-detecting devices often found in smartphones and exercise trackers—on their wrists for seven days to measure activity, and they completed questionnaires to assess depression symptoms and cognitive function.

The analysis showed that 37.6% of participants rose early in the morning, stayed active throughout the day and had consistent daily routines.

Another group comprising 32.6% of participants similarly had consistent daily patterns but the participants were active for an average of just 13.4 hours each day because they rose later in the morning or settled down earlier in the evening. This group had more depression symptoms and poorer cognition t