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Research identifies the herbal supplements that are effective in treating anxiety

Global Neuroscience Initiative Foundation, October 6, 2022

A systematic review of research into the use of nutritional supplements for the treatment of anxiety disorders has found strong evidence for the use of extracts of passionflower or kava and combinations of L-lysine and L-arginine. Researchers writing in open access Nutrition Journal pooled the results of 24 studies involving a total of more than 2000 participants, showing that some nutritional and herbal supplements can be effective, without the risk of serious side effects.

The research was carried out by Shaheen Lakhan and Karen Vieira from the Global Neuroscience Initiative Foundation, a non-profit charity organization for the advancement of neurological and mental health patient welfare, education, and research, based in Los Angeles, USA. Lakhan said, “Our review and summary of the literature on herbal remedies and dietary supplements for anxiety should aid mental health practitioners in advising their patients and provide insight for future research in this field. We found mixed results – while passionflower or kava and L-lysine and L-arginine appeared to be effective, St John’s Wort and magnesium supplements were not”.

Of the studies included in the review, 21 were randomized controlled trials. Of these, 15 showed positive effects from either a nutritional or herbal remedy and any reported side effects were mild to moderate.

Melatonin improves mitochondrial function in rat model of diabetes

University of Granada, La Paz University Hospital & University of Texas,  October 6 2022. 

The Journal of Pineal Research published an article by researchers that reported a protective effect for melatonin on mitochondrial function in obese rats.

“Mitochondrial dysfunction in adipose tissue may contribute to obesity-related metabolic derangements such as type 2 diabetes mellitus,” write principle investigator Ahmad Agil and colleagues. “Because mitochondria are a target for melatonin action, the goal of this study was to investigate the effects of melatonin on mitochondrial function in white and beige inguinal adipose tissue of Zücker diabetic fatty rats.

The team divided eight diabetic rats and eight lean littermates to receive melatonin-enhanced or plain drinking water for six weeks, after which mitochondrial function was evaluated. They observed improvement in mitochondrial respiration, and a reduction in oxidative status among both lean and obese animals that received melatonin. 

He observed that, along with other factors, the rise in obesity in both developed and developing countries has coincided with exposure to artificial light at night, which inhibits the body’s production of melatonin.  The inhibition of melatonin production that occurs when a lamp, computer or television is left on leads to disrupted sleep and an increased risk of weight gain, which negatively impacts the mitochondria, promoting insulin resistance and diabetes. “For all these reasons, it is important to try to sleep in absolute darkness, to avoid interference in the generation of melatonin,” Professor Agil noted.

Walking can reduce breast cancer risk

American Cancer Society, October 4, 2022

Postmenopausal women who were very active or walked for at least seven hours a week had a reduced risk for breast cancer, according to a study published in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research.

Women who engaged in at least an hour of vigorous physical activity every day had a 25 percent lower risk for breast cancer, and those who walked for at least seven hours a week had a 14 percent lower risk for bre