The Gazette of Medical Sciences Podcast - The Science of Healing

Drug Repurposing for Parkinson’s Disease with Deep Learning

Can existing drugs reveal new possibilities for Parkinson’s disease research?

In this episode of The Gazette of Medical Sciences Podcast, we explore the research article “Drug Repurposing for Parkinson’s Disease with Deep Learning: A Virtual Screening Approach” by Dr. Kiran Vokkarne and Dr. Raji Sundararajan, School of Engineering Technology, Purdue University, USA.

The study investigates how artificial intelligence, deep learning, drug repurposing, virtual screening, and drug-target interaction prediction can be used to identify existing drugs that may warrant further investigation for Parkinson’s disease. Using DeepPurpose, a Python-based deep-learning framework, the researchers screened drug candidates against biological targets associated with Parkinson’s disease.

The computational screening identified Remdesivir, Metformin, and Simvastatin among the drugs showing high scores compared with Levodopa. The study also considers biological relevance, blood-brain barrier and CNS impact, mechanism alignment, literature, and safety in its multifactor assessment.

Importantly, these computational findings do not establish these drugs as treatments for Parkinson’s disease. The research highlights the need for laboratory validation and further in-vitro investigation before potential clinical translation.

Read the full research article:

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Submit your article to The Gazette of Medical Sciences. Selected published research can be transformed into an engaging medical science podcast for wider scholarly outreach.

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Topics: Parkinson’s disease, drug repurposing, medical podcast, medical research, drugs, deep learning, artificial intelligence in medicine, AI in healthcare, virtual screening, drug discovery, drug-target interaction, neuroscience, neurology, computational biology, machine learning, DeepPurpose, Metformin, Levodopa, medical science, healthcare research.

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What happens when surveillance technology is misused or when potentially important digital evidence is not presented?

In this episode of The Gazette of Medical Sciences Podcast,Dr. Michael Kirk Moore examines automated license-plate readers, cellphone location data, body-camera records, privacy, police accountability, and the constitutional implications of warrantless tracking. Drawing on cases discussed in his published perspective article, Dr. Moore asks whether surveillance technology is used and disclosed consistently and who watches those entrustedwith operating these powerful systems.

This thought-provoking discussion connects medical science,public health, public policy, ethics, technology, law, privacy, and institutional accountability. The interpretations presented in this episode reflect the author’s analysis and perspective.

Stay informed, question what is visible, and consider whatmay be missing.

If you are interested in creating a podcast in your ownvoice, send your article to: [email protected]

or submit it here:

https://www.thegms.co/manuscript-submission-form/ The Gazette of Medical Sciences

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In this episode of The Gazette of Medical Sciences Podcast, we explore another insightful work by Dr. Ken Thorp, examining breast cancer through the broader perspectives of hormonal regulation, circadian rhythms, circulation, and energy dynamics within the body.

This discussion revisits traditional ideas in cancer research and explores how physiological rhythms, extracellular energy patterns, blood circulation, and systemic regulation may influence breast cancer and chronic disease processes. The episode also discusses melatonin, metabolic activity, electromagnetic fields, and the interconnected nature of human physiology.

This episode is part of the ongoing series, Uncovering the Energy Dynamics Behind Chronic Diseases.

The full article can be read and downloaded from the Gazette of Medical Sciences website at TheGMS.co

For article submissions, collaborations, and podcast development, write to us:
[email protected]

Energy Dynamics in Seizure Disorder – Dr. Ken Thorp

Read or download the full article:⁠ https://www.thegms.co/neurology/neuro-rw-23120501.pdf⁠

Interested in turning your research into a podcast?Submit your published or unpublished articles to: ⁠[email protected]⁠

In this episode of Science of Healing – The Gazette of Medical Sciences Podcast, we explore the intricate relationship between energy dynamics and seizure disorders, based on the work of Dr. Ken Thorp.

Seizure disorders involve complex neurological processes, where alterations in cellular energy metabolism may play a critical role in the onset and progression of abnormal brain activity. This episode presents key insights into how energy balance, neuronal function, and metabolic pathways interact in the context of seizures.

Designed for researchers, clinicians, and those interested in neurological science, this podcast translates scientific findings into an accessible and engaging audio format, extending the reach of research beyond traditional publication.

In this episode, we explore the impactful work of the Hackett Hemwall Patterson Foundation and the World Health Access Team during their medical mission in Honduras. Based on the article by Dr. Nav Yash Gupta, this discussion highlights global health outreach, medical missions, physician training, community health education, and healthcare access in underserved regions.

Discover how international collaboration, clinical training, and compassionate care initiatives contribute to sustainable public health development and health equity.

The episode focuses on global health, medical missions, Honduras healthcare, public health outreach, physician training, health equity, community medicine, and international healthcare collaboration.

Read the full report:
https://www.thegms.co/publichealth/pubheal-gr-26220101.pdf

Interested in converting your published research into an academic podcast episode?
Submit your article here:
https://www.thegms.co/manuscript-submission-form/

In this episode of The Gazette of Medical Sciences Podcast- Science of Healing, we explore a novel perspective on chronic disease that moves beyond isolated organs and traditional mechanical explanations.

Based on published research of Dr. Ken Thorp, this discussion examines how alterations in energy dynamics within the blood and cardiovascular system may underlie the interconnected progression of chronic heart failure, chronic kidney disease, and the cardiorenal syndrome. The episode highlights the systemic nature of these conditions and offers insights into how vascular function, circulation, and energy balance influence organ health across the body.

Read the full article:

Interested in publishing or podcasting your research?
We welcome article submissions and podcast collaborations.
Email: [email protected]

In this episode of The Gazette of Medical Sciences Podcast – Science of Healing, we explore the concept of energy dynamics in dementia and neurodegenerative diseases, based on published research title, Energy Dynamics in Dementia & the neurodegenerative diseases: A New Causal Paradigm.

The discussion examines how alterations in cellular and systemic energy balance may influence disease progression, adaptation, and neurological function.

This podcast is part of our ongoing series, Uncovering the Energy Dynamics Behind Chronic DiseasesRead the full article here- https://www.thegms.co/neurology/neuro-rw-22062901.pdf

Call for Articles & Podcast Development
Researchers and clinicians are invited to submit original articles, reviews, and clinical perspectives for publication and podcast adaptation.

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Stay connected with The Gazette of Medical Sciences as we continue uncovering new perspectives in medical research and healing science.

In this episode, we explore Dr. Ken Thorp’s groundbreaking work on the energetic foundations of autoimmune disorders. The discussion reveals how changes in the heart’s rhythmic energy and the blood’s vitality can influence immune balance, inflammation, and the body’s overall harmony — offering a unified view of immunity rarely discussed in modern medicine.

This episode is part of Uncovering the Energy Dynamics Behind Chronic Diseases Podcast Series, featuring original research and innovative ideas that challenge conventional medical thinking.

Read this work and explore other articles at www.thegms.co

You are also invited to submit your own research for publication or podcast production.
For any query, contact us at [email protected] or [email protected]

Energy Dynamics in the Metabolic Syndrome is Episode no. 3 in the ongoing series - Uncovering the Energy Dynamics Behind Chronic Diseases. This episode explores how the liver, pancreas, fat cells, brain, and mitochondria interact through complex hormonal signals to regulate metabolism. This episode unpacks the critical links between insulin resistance, hormonal imbalances, and disrupted energy pathways that define the metabolic syndrome.

At The Gazette of Medical Sciences (TheGMS), we not only publish medical research but also bring it to life through podcasts on Spotify and Apple Podcasts—making your work accessible to a global audience of clinicians, researchers, and health enthusiasts.

We invite you to listen, learn, and contribute. If you have research, reviews, or observations related to energy metabolism, metabolic disorders, or broader medical science, submit your work to TheGMS. Your article can be published and also podcasted to reach thousands worldwide.

Submit your manuscripts directly by email at [email protected] for immediate acknowledgment and consideration.

In this first episode of Uncovering the Energy Dynamics Behind Chronic Diseases, we explore a profound shift in perspective presented in the work by Dr. Ken Thorp. This episode delves into how COVID-19 may not only be a viral illness, but also a systemic energy-depletion syndrome that disrupts protein folding, leads to amyloid formation, and triggers widespread biological dysfunction.

We discuss how energy collapse within cells may be the root cause of clotting, autoimmunity, and neurological symptoms — moving beyond the surface of immune reactions to the deeper mechanics of prion-like behavior and biophysical imbalance. This paradigm offers a unified framework for understanding both acute COVID and long-haul cases.

This work is published in The Gazette of Medical Sciences under the title:
“COVID-19: Energy, Protein Folding & Prion Disease” (2022)
Access the full work here: https://doi.org/10.46766/thegms.neuro.22083101

The Gazette of Medical Sciences Podcast brings research to life through audio. Subscribe for more episodes in this series highlighting Dr. Thorp’s ongoing contributions to understanding the hidden energy dynamics behind modern chronic illnesses.