Kidney Wellness with Dr. Bismah

The Hidden Hormone Destroying Your Kidneys (Doctors Never Test This)


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In this episode of Wellness Focused, I take a closer look at a hormone most kidney patients are never told to think about—testosterone—and why ignoring it may come at a real cost to kidney health.


Over years of clinical practice, I kept seeing men with chronic kidney disease who were doing everything “right,” yet their kidney function continued to decline. When I followed the research outside conventional nephrology training, a striking pattern emerged: low testosterone was common, rarely tested, and strongly linked to faster kidney deterioration, anemia resistance, muscle loss, and higher cardiovascular risk.

I walk through long-term studies showing how addressing testosterone deficiency can dramatically alter kidney outcomes, explain the biological mechanisms connecting hormones and renal function, and describe how kidney disease itself further suppresses testosterone—creating a self-perpetuating cycle.

I also discuss why standard care often misses this connection, which symptoms should raise concern, and which hormone tests actually matter. This is not about anti-aging or optimization trends—it’s about identifying a missing variable that may help stabilize kidney disease and improve quality of life when addressed thoughtfully and safely.

This episode is meant to help patients and clinicians look beyond assumptions and ask better questions about what may truly be driving kidney decline.


Low testosterone may accelerate kidney disease—Dr. Bismah explains the science, risks, and why hormone testing matters for men with CKD.


I’m Dr. Bismah Irfan, MD, a board-certified nephrologist and functional medicine physician. I help patients with kidney disease and complex immune conditions navigate personalized, evidence-based strategies to protect long-term health and avoid preventable complications.


Bismah Irfan, MD

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Kidney Wellness with Dr. BismahBy Bismah Irfan, MD