"The House of Horror," despite its pulp sensibilities, clearly resonates with the Poe-esque tradition of detective fiction intertwined with the macabre and the sensation novel. Like Poe's tales, Quinn's story utilises a combination of rational investigation and visceral horror to create a sense of dread and suspense. De Grandin, though more flamboyant than Poe's Dupin, embodies the detective figure who seeks to unravel a dark mystery through observation and deduction. The story shares Poe's fascination with the grotesque and the psychologically disturbed, as exemplified by the character of Dr. Marston and his horrifying experiments.

While Quinn's style is less atmospheric and more reliant on plot-driven thrills than Poe's, "The House of Horror" nonetheless shares a common lineage in its blend of mystery, horror, and a fascination with the darker aspects of human nature.

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