“Three months after taking these tablets, she was 80 per cent better—without the risk, expense and everything that went with those procedures.”
“It is life-changing for a lot of patients, and it has been a real practice changer for me.”
What if one of the most effective treatments for melasma isn’t a topical cream or laser—but a low-dose oral medication?
In this episode of JCMS Author Interviews, Dr. Kirk Barber speaks with Vancouver dermatologists Dr. Vincent Richer and Dr. Allison Sutton about their article, “Low-Dose Oral Tranexamic Acid as a Standard Treatment for Melasma: Are We There Yet?”, published in the May/June issue of the Journal of Cutaneous Medicine and Surgery.
Dr. Richer and Dr. Sutton explain why oral tranexamic acid has become a practice-changing treatment for many of their patients. They discuss its effectiveness compared with topical treatments and laser procedures, including cases in which patients have experienced dramatic improvements after only a few months.
The conversation also addresses the questions surrounding longer-term use. Because melasma is a chronic condition that frequently returns when treatment stops, should oral tranexamic acid be continued beyond the three-to-six-month period typically studied in clinical trials?
Drs. Richer, Sutton and Barber examine dosage, patient screening and the risk of thrombosis, as well as considerations involving oral contraceptives, hormone replacement therapy, pregnancy and sun exposure. They also explore the continuing role of sunscreen, hydroquinone, botanical brighteners and laser therapy in a comprehensive treatment plan.
A practical and potentially practice-changing discussion about treating melasma safely, effectively and for the long term.
Dr. Vincent Richer is a clinical faculty member in the Department of Dermatology and Skin Science at the University of British Columbia. He practises at Pacific Derm in Vancouver, with a focus on medical and cosmetic dermatology, laser surgery and pigment disorders.
Dr. Allison Sutton is a clinical faculty member in the Department of Dermatology and Skin Science at the University of British Columbia and the founder of West Dermatology in Vancouver. Her practice focuses on cosmetic and aesthetic dermatology.
Dr. Barber and his guests do not receive any financial reimbursement for the production of this podcast.
For more great CDA podcasts check out Dermalogues, our Residents podcast hosted by Dr Kerri Purdy. New episodes are coming out in October 2026.
To learn more about the work of the Canadian Dermatology Association, please visit our website at dermatology.ca
This podcast is produced by David McGuffin and Graham McGuffin of ExploreProductions.ca