Physician's choice: a survey has shown that less than half of US doctors would choose a career in medicine if they had the choice again. Also discussed this week, abortion in Cuba, 9/11 cancer cases, and child maltreatment.

The pursuit of happiness: Jeffrey Sachs joins us to discuss the World Happiness Report 2013. Also, Sci-Fi medicine (an implantable, immune-reprogramming cancer vaccine)...

Violent crackdown: Kristin Solberg joins us from Cairo to discuss the human rights abuses, deaths, and consequences of the violent crackdown that started on Aug 14 in the city...

Chemical weapons: WMD expert Stephen Cantrill joins us to discuss symptoms, treatment options, and the history behind chemical weapons and nerve agents...

Cleaning up from oil: Brazil promises a cut of oil reserves to fund health and education, while the health effects of Deepwater Horizon disaster rumble on...

Syria's problems: Unique problems mean tough decisions over the health of Syria's 1.6 million refugees. We speak with Paul Spiegel from UNHCR about the challenges he faces in providing this care...

Neglected no longer: moves to get mycetoma onto the WHO neglected tropical disease list, continuing success for HIV/AIDS programmes in east and southern Africa...

The Datakeepers: Big Pharma have proposed a new voluntary commitment to (moderated) data sharing. Is it a genuine attempt to open up or just a protective cushion of bureaucracy?...

HIV, MSM, LDN: Incidence of HIV is rising in London's gay scene. We find out why. We also assess the pandemic potential of MERS coronavirus, appraise a titanic new cancer gene database, and round up The Lancet's best news and feature content.

Duck and cover: what preparations are being made in case of a nuclear explosion? We talk to NAACHO's Jack Herrmann about planning the response in the USA. Also in the show, river blindness and the Carter Center...