Too busy to read the Lens? Listen to our weekly summary here! In this week’s episode we discuss…

• When the American Joint Committee on Cancer’s classification for uveal melanoma is challenged, a new staging system is proposed that incorporates tumor volume, clinical risk factors, and genetic alterations.
• GLP-1 receptor agonists are linked to a >90% reduced risk over 10 years of developing nonexudative age-related macular degeneration when compared to other weight-loss drugs in obese, non-diabetic individuals.
• Migraines are independently associated with higher rates of central serous chorioretinopathy when compared to controls.
• Eye drops containing siRNA (GalNAc-modified siHOTAIR) are comparable to anti-VEGF injections, suppressing inflammation, vascular mediators, endothelial permeability, and angiogenesis in diabetic rats.