This Chapter from the Yellow Emperor's Classic of Internal Medicine explores the relationship between organ variations and health. Qi Bo, responding to the Yellow Emperor's inquiries, details how size, position, and firmness of the five zang organs (heart, lungs, liver, spleen, kidneys) and six fu organs influence susceptibility to illness. He explains that these variations, totaling 25, manifest externally and can be observed to diagnose internal conditions. The text further examines how these organs correlate with other bodily components, such as skin, muscles, and bones, to provide a holistic understanding of health and disease. Finally, it discusses the relationship between the five zang and six fu organs and their external manifestations.