The Loop Podcast: Peptides, Longevity & Women’s Wellness

You don't need an entirely new wardrobe to refresh your style. Sometimes, all it takes is looking at the clothes you already own in a completely different way.

This week on The Loop Podcast, Stephanie Gambetta welcomes back stylist Dina for her third appearance to talk about fall fashion, personal style, and getting more out of your closet without constantly buying something new.

Stephanie shares how Dina helped her put together an entire wardrobe for a recent mother-daughter trip to New York using only pieces she already owned. From unexpected outfit combinations to mixing designer investments with affordable finds, they discuss how a few small styling changes can make familiar clothes feel completely new.

They also break down the fall trends worth paying attention to, including barrel jeans, cigarette jeans, rich textures, brooches, statement accessories, layering, boots, and the return of more expressive fashion. Dina shares practical advice for adapting trends to your body type, lifestyle, and climate rather than feeling pressured to wear whatever happens to be popular.

The conversation goes beyond fashion as Stephanie and Dina discuss how our relationships with clothing change through different stages of life, especially when our bodies change. They explore the importance of finding clothes that fit and feel good today, letting go of arbitrary size labels, and using personal style as a form of confidence and self-expression.

Whether you're updating your fall wardrobe, figuring out how to dress for your body, or simply looking for new ways to wear what you already have, this episode is full of approachable styling ideas and reminders that great style should feel like you.

- Join the Loop Health Community: https://loop.health

- Signup for Loop Beauty Launch Updates: www.loop-beauty.com 

Book a 1:1 coaching call with Stephanie for 30% off: https://calendly.com/stephanie-theloopway/steph-45-minute-q-a-with-peptide-coach-clone

Send us Fan Mail

What does the energy of your home have to do with your relationships, mindset, and the way you move through life?

This week on The Loop Podcast, Stephanie Gambetta sits down with Heather Askinosie to explore the world of feng shui, crystals, energy, and the connection between our surroundings and personal growth.

Heather shares how an unexpected introduction to classical feng shui during her career in luxury real estate led her down a completely different path. She explains how she approaches the energy of a home, why she believes certain spaces can influence relationships and financial success, and how she now incorporates crystal readings and frequency work into her practice.

Stephanie shares the personal story behind finding her California home after her divorce and how her own experiences with injury, breathwork, and rebuilding her life have changed the way she thinks about healing and personal transformation. Together, they discuss feminine energy, self-worth, nervous system regulation, and the pressure women often feel to constantly be doing more.

They also explore why midlife can be such a powerful time to question old beliefs, reconnect with your intuition, and get clear about what you actually want. Heather offers her perspective on manifestation, creating more intentional spaces, and finding simple daily practices that work for you without turning wellness into another overwhelming checklist.

From the meaning behind the artwork in your bedroom to the importance of slowing down and allowing yourself to receive, this conversation takes a different approach to the topics we often discuss on Loop. It's an open-minded look at spirituality, personal growth, and the possibilities of your next chapter.

Heather's perspectives on feng shui, crystals, and frequency work are spiritual wellness approaches rather than scientifically established medical treatments.

https://substack.com/@heatheraskinosie

- Join the Loop Health Community: https://loop.health

- Signup for Loop Beauty Launch Updates: www.loop-beauty.com 

Book a 1:1 coaching call with Stephanie for 30% off: https://calendly.com/stephanie-theloopway/steph-45-minute-q-a-with-peptide-coach-clone

Send us Fan Mail

What can your blood work actually tell you about your health, and how do you know if your peptides, supplements, and hormone therapies are making a difference? This week on The Loop Podcast, Stephanie Gambetta welcomes back Polo from the Loop Health team to take a closer look at her latest lab results and the changes she's seen over the past five months.

Stephanie opens up about her health journey over the last year and a half, from struggling with a kidney infection, low energy, and elevated liver enzymes to seeing improvements in several of her biomarkers. Together, Stephanie and Polo discuss her experiences with peptides like MOTS-c, Thymosin Alpha-1, and GLP-1s, along with the role of supplements, nutrition, and consistency. They also explore why body composition matters more than the number on the scale, especially for women navigating midlife and menopause.

But not every result was positive. Stephanie shares her ongoing challenges with genetically elevated cholesterol, including her LDL, ApoB, and lipoprotein(a) levels, and discusses her plans to investigate cardiovascular risk further. They also break down changes in her estrogen and testosterone levels, her experience with hormone pellets, and why she's considering adjustments to her routine.

Throughout the conversation, Stephanie and Polo emphasize the importance of understanding your own biomarkers, working with qualified healthcare providers, and making changes based on your individual needs rather than following someone else's wellness routine. From blood testing and hormone health to peptides, supplements, and longevity, this episode offers a personal look at the progress, setbacks, and ongoing decisions involved in Stephanie's health journey.

This episode is for educational purposes only and does not constitute medical advice. Individual lab testing schedules and treatment decisions should be discussed with a qualified healthcare professional.

Peptides & Compounds Mentioned

• MOTS-c
• Thymosin Alpha-1
• BPC-157
• KPV 
• GLP-1 receptor agonists
• 5-Amino-1MQ
• NAD+

- Join the Loop Health Community: https://loop.health

- Signup for Loop Beauty Launch Updates: www.loop-beauty.com 

Book a 1:1 coaching call with Stephanie for 30% off: https://calendly.com/stephanie-theloopway/steph-45-minute-q-a-with-peptide-coach-clone

Send us Fan Mail

What if feeling better in midlife starts with understanding how your gut, hormones, stress, and overall health are connected? This week on The Loop Podcast, Stephanie Gambetta welcomes Kate Gordin, founder of Four Body Connection, a holistic wellness practice outside Chicago, to talk about gut health, bioenergetics, peptides, and taking a more personalized approach to wellness.

Kate shares the health challenges that led her to completely change careers, including thyroid issues, long COVID, and a frightening experience that left her struggling to breathe. What began as a search for answers eventually became a new purpose, leading her to study functional wellness, gut health, bioenergetics, and mindset coaching. Stephanie and Kate discuss how stress and emotional experiences can affect the way we feel, why gut health deserves more attention, and how overwhelming it can be to navigate supplements, hormones, testing, and conflicting wellness advice.

They also dive into their personal experiences with peptides, including hair shedding during perimenopause, inflammation, injury recovery, and strength training. Kate shares how her health journey has changed her confidence and what it means to feel stronger at 50, while Stephanie opens up about her own approach to blood work, hormones, and building a wellness routine that fits real life.

Beyond the physical side of health, this conversation is about reinvention. From changing careers and finding purpose to letting go of limiting beliefs, Stephanie and Kate explore why midlife can be an opportunity to build a life that feels healthier, stronger, and more fulfilling.

This episode shares personal experiences and wellness perspectives for educational purposes. Some peptide applications and bioenergetic approaches discussed have limited clinical evidence and are not established treatments for the conditions mentioned.

Peptides Mentioned:

BPC-157

TB-500

KPV 

GHK-Cu 

Klotho

- Join the Loop Health Community: https://loop.health

- Signup for Loop Beauty Launch Updates: www.loop-beauty.com 

Book a 1:1 coaching call with Stephanie for 30% off: https://calendly.com/stephanie-theloopway/steph-45-minute-q-a-with-peptide-coach-clone

Send us Fan Mail

Certified nutrition and macro coach Megan Kohrs joins Stephanie Gambetta to talk about building a healthier relationship with food, understanding macronutrients, and why eating less isn't always the answer when you're trying to lose fat or build muscle. Megan shares her personal experience with eating disorders, body dysmorphia, gut health issues, and food sensitivities, and how learning to properly fuel her body changed her approach to nutrition. She also shares how her journey eventually led her to become part of the Loop Health coaching team.

Stephanie and Megan break down what macros actually are, why protein is especially important for women in midlife, and how to build balanced meals without obsessing over every calorie. They discuss the challenges of eating enough while taking GLP-1 medications, maintaining muscle during weight loss, and why strength training and proper nutrition need to work together. Megan also opens up about her experience with mast cell activation syndrome (MCAS), histamine reactions, and her personal experience using peptides as part of her wellness journey.

Beyond nutrition, they explore the emotional side of food, from overcoming restrictive eating patterns and letting go of food guilt to enjoying vacations, restaurants, and everyday life without constantly worrying about weight gain. They also discuss motherhood, finding purpose outside of raising children, and why building confidence and a supportive community can be just as important as the food on your plate.

The goal isn't another restrictive diet. It's learning how to fuel your body, build strength, and create a healthy lifestyle you can actually enjoy.

This episode is for educational purposes only and does not constitute medical or nutritional advice. Consult a qualified healthcare professional for individualized guidance, particularly regarding eating disorders, GLP-1 medications, and peptides.

Peptides & Compounds Discussed

GLP-1 medications, including tirzepatide; KPV; BPC-157 (the transcript appears to reference it, but the wording is garbled); MOTS-c; and Selank/Semax in the closing discussion.

Want to book a nutrition coaching session with Meg?  Find her at www.megkohrswellness.com

Follow her on instagram @megkohrswellness

- Join the Loop Health Community: https://loop.health

- Signup for Loop Beauty Launch Updates: www.loop-beauty.com 

Book a 1:1 coaching call with Stephanie for 30% off: https://calendly.com/stephanie-theloopway/steph-45-minute-q-a-with-peptide-coach-clone

Send us Fan Mail

Master life coach and spiritual psychologist Christine Hassler joins Stephanie Gambetta for a conversation about personal growth, emotional healing, and what it really means to trust yourself. With over 20 years of coaching experience, Christine shares why so many women struggle with people-pleasing, perfectionism, and the need for outside validation, and how reconnecting with your inner authority can change the way you approach relationships, career, motherhood, and everyday life.

Stephanie also opens up about her own experience working with Christine, including navigating uncertainty, surrendering control, and learning to approach difficult emotions with more compassion. Together, they explore breathwork, emotional release, old survival patterns, jealousy, comparison, and why personal growth doesn't mean you'll never struggle with the same things again. They also discuss finding confidence as women get older, the changing coaching industry, the importance of finding your own answers, and how to recognize when you're giving too much power to other people's opinions.

Christine also shares stories about meeting Joe Rogan, finding love, and learning to embrace desire without turning it into suffering. They wrap up with a conversation about postpartum inflammation, peptides, and what Christine hopes to pass on to the next generation. Whether you're navigating a major life transition, feeling stuck in old patterns, or simply ready to reconnect with yourself, this episode is about learning to trust who you are instead of constantly searching for answers outside yourself.

This episode is for educational purposes only and should not be considered medical or mental health advice.

- Join the Loop Health Community: https://loop.health

- Signup for Loop Beauty Launch Updates: www.loop-beauty.com 

- Book a 1:1 coaching call with Stephanie for 30% off: https://calendly.com/stephanie-theloopway/steph-45-minute-q-a-with-peptide-coach-clone

Send us Fan Mail

Stephanie Gambetta starts this episode with a solo update on what’s happening with Loop Health, her current peptide routine, the upcoming Loop Beauty line, and some of the changes she’s making in her own health at 51. She talks about building muscle in midlife, improving her sleep during menopause, prioritizing recovery, monitoring her blood work, and the mitochondrial stack she’s currently using. She also gets personal about the realities of building Loop Health, navigating life without Instagram, experimenting with TikTok, and making more time for friendships, travel, and the things that actually fill her back up. 

Then Stephanie sits down with Aabid Farukhi, a board-certified musculoskeletal radiologist, to break down DEXA scans and why the number on your bathroom scale doesn’t tell the whole story. They explain how a DEXA scan measures muscle mass, body fat, visceral fat, bone density, and even muscle symmetry between different sides of your body. Stephanie also walks through her own DEXA results, including gaining a pound of muscle while microdosing a GLP-1, and shares why she uses these scans to see whether her training, nutrition, peptides, and lifestyle are actually changing her body composition. 

Stephanie and Aabid also dig into one of the biggest concerns surrounding GLP-1s: losing muscle and bone mass while losing weight. They discuss resistance training, protein, visceral fat, bone health during perimenopause and menopause, and why tracking body composition can give you a much clearer picture of your progress than obsessing over weight alone. Whether you’re using GLP-1s and peptides or simply trying to build muscle, lose fat, and stay strong as you age, this episode is about understanding what’s actually happening inside your body. 

This episode is for educational purposes only and should not be considered medical advice. Always consult qualified healthcare professionals before beginning or changing medications, peptides, supplements, hormones, or other treatments.

Peptides & Compounds Discussed

• SS-31
• MOTS-c
• 5-Amino-1MQ
• NAD+
• Thymosin Alpha-1
• KPV
• GLP-1 receptor agonists
• Glutathione
• GHK-Cu
• Progesterone
• Magnesium
• Creatine

LOOPHEALTH20 to get 20% off a dexascan with Dexafit OC (https://www.oc.dexafit.com/)

Send us Fan Mail

Psychologist Dr. Sarah Sarkis returns to The Loop Podcast to talk about the psychology of midlife and why the changes that happen in your 40s and 50s can feel so uncomfortable. Stephanie and Sarah break down the idea of a “midlife crisis” and look at what’s actually happening when your identity, relationships, career, family life, hormones, and priorities all begin shifting at the same time. Sarah explains why discomfort doesn’t necessarily mean something is wrong, how the things that worked earlier in life may need to be upgraded, and why the whispers telling you something needs to change can eventually become impossible to ignore. 

Stephanie also shares what this has looked like in her own life, from divorce and rebuilding her identity to the recent challenges with Instagram, postponing her Loop event, and unexpectedly finding a new creative outlet on TikTok. They talk about what happens when your growth makes the people around you uncomfortable, why progress includes plateaus and even periods of regression, dealing with comparison and rejection, grieving an old version of your life, and learning to keep moving when you have no idea exactly where you're headed. Sarah also shares a different way to think about whether a major life change is “working”: sometimes constantly measuring your progress is perfectionism disguised as excellence.

Stephanie and Sarah also preview the upcoming Aspen retreat, where Sarah will help women explore the stories they’re carrying into midlife, decide which ones still serve them, and become more intentional about what they want the next chapter of their lives to look like.

Join Steph & Dr. Sarkis at the Loop retreat ( http://www.theloopway.com/events/aspen ), $500 off exclusively for podcast listeners available here: 
https://buy.stripe.com/8x27sKfz30JKb1S7jo3gk01

Send us Fan Mail

Karen Martel, CEO of Midlife Solutions, joins Stephanie Gambetta for a candid conversation about perimenopause, menopause, hormone replacement therapy, peptides, GLP-1s, and what actually changes in a woman’s body during midlife. Karen shares how her own experience being pushed into early menopause at 42 changed the direction of her career, despite already working as a nutritionist and doing everything she thought was “right.” She and Stephanie break down the early signs of perimenopause, progesterone and estrogen loss, stubborn midlife weight gain, brain fog, mood changes, and why you can’t always diet, exercise, or biohack your way out of hormonal changes.

Stephanie also opens up about her own HRT journey at 51, including progesterone, estrogen, testosterone pellets, and the changes she’s currently navigating. Together, she and Karen discuss why HRT and peptides can work together rather than compete, combining GLP-1s with optimized hormones, microdosing, food noise, preserving muscle, thyroid health, and why some women plateau on GLP-1s even at higher doses. They also get into starting HRT later in life, overdoing biohacking, wearable data, DEXA scans, peptide safety, and why women need individualized protocols instead of copying whatever someone else is taking online.

Karen and Stephanie also challenge the idea that suffering through menopause deserves a badge of honor. The goal isn’t perfection or doing every wellness trend imaginable. It’s understanding your body, finding the right tools, and building a sustainable approach that helps you feel strong, confident, and healthy through the second half of life.

Use code LOOP10 for 10% off at Midlife Solutions.

Shop Midlife Solutions

This episode is for educational purposes only and should not be considered medical advice. Always consult qualified healthcare professionals before beginning or changing hormones, medications, peptides, supplements, or other treatments.

Peptides, Hormones & Compounds Discussed

• Hormone Replacement Therapy (HRT)
• Estrogen
• Progesterone
• Testosterone
• GLP-1 receptor agonists
• Retatrutide
• GHK-Cu
• TB-500
• BPC-157
• MOTS-c
• Tesamorelin
• Thyroid medication

Send us Fan Mail

Sienna Olson, founder of SLO Rx, joins The Loop Podcast for a conversation about what happens when you’re doing everything “right” but your body still isn’t responding. Sienna holds a Doctorate in Chiropractic and a Master’s in Sports Medicine, and her own journey from ski racing and bodybuilding to gaining 50 pounds in five months changed the way she thinks about metabolism, body composition, and women’s health. Today, she works with women who are juggling careers, families, and packed schedules but still wondering why their energy is low and their hard work isn’t showing up in the mirror. Her philosophy is simple: more isn’t better, right is.

Stephanie and Sienna break down GLP-1s, peptides, protein, resistance training, body composition, and why simply increasing a dose or adding another wellness tool isn’t always the answer. They discuss tirzepatide versus retatrutide, microdosing, BPC-157, why Sienna takes a conservative approach to peptides, and how the scale can completely distort your perception of progress when you’re building muscle. They also get into comparison, consistency, sleep, finding a sustainable routine, and giving women permission to want to feel healthy, strong, confident, and hot without apologizing for it. It’s a conversation about getting away from quick fixes and finding the tools that actually fit your body and your life. 

Peptides & Compounds Discussed

• Tirzepatide
• Retatrutide
• GLP-1 receptor agonists
• BPC-157
• Selank
• Semax
• Microdosing GLP-1s / peptide protocols

This episode is for educational purposes only and should not be considered medical advice. Always consult qualified healthcare professionals before beginning or changing medications, peptides, supplements, training, or other treatments.

Send us Fan Mail