The MaML Podcast - Medicine & Machine Learning

Pat Walters is the Chief Data Officer and Patrick Riley is the senior VP of AI from Relay Therapeutics in Cambridge, MA. In this episode we discuss Relay's innovative approach to drug discovery, and how new developments in AI and computational modeling have accelerated this process.

Matt Diamond, MD, PhD, is Chief Medical Director of the FDA’s Digital Health Center of Excellence. Dr. Diamond provides leadership for digital health policy development and implementation for emerging technologies including artificial intelligence. Prior to joining the Agency, Dr. Diamond served on leadership teams of large and small technology companies, including as Chief Medical Officer at Nokia, and as Medical Director at Fossil Group. He earned his MD and PhD (biophysics) from the Mount Sinai School of Medicine, and is board certified in rehabilitation medicine and sports medicine and certified in medical acupuncture.

TIMESTAMPS

1:15 tell us about your path

5:15 what’s a typical day like

8:26 how would you define a digital health technology?

10:50 regulation of medical devices is based on their intended use

13:00 are AI technologies fundamentally different from a stethoscope

19:30 talking about new FDA guidelines - Digital Health Technologies for Remote Data Acquisition in Clinical Investigations

27:00 collaborative communities (join one!)

30:00 FDA & relationships with companies

37:00 what do you think the future of AI in medicine will look like?

39:55 what advice would you give yourself

Contact us! [email protected]

Host: David Wu / Twitter: @davidjhwu

Producer: Aaron Schumacher / Twitter: @a_schu95

Artwork & Video: Saurin Kantesaria

Music: Caligula - Windows96. Used with Artist Permission.

Joy Kincaid is our guest today from OncoHealth, which has just launched their new digital telehealth platform supporting cancer patients and their families. Joy was formerly VP of Population Health at Optum.

1:06 “So our first question is.. tell us about your path”

7:25 talking about Optum

11:50 OncoHealth

13:48 Iris Digital Health platform

37:35 Talking about the Healthcare Industry

45:56 future of digital medicine in 10-20 years?

48:40 “the movement of the Tao is returning”

51:45 advice to recent grads

53:30 intentional networking

57:50 what gives your life meaning?

Host: David Wu / Twitter: @davidjhwu

Producer: Aaron Schumacher / Twitter: @a_schu95

Artwork & Video: Saurin Kantesaria

Description: Margaret Elizabeth Ross, M.D., Ph.D. is a Nathan Cummings professor in neurology and director of the Center for Neurogenetics at the Feil Family Brain and Mind Research Institute at Weill Cornell Medicine in New York. To learn more, check out the Ross Lab website! 

1:30 Introduction

4:00 An Intro to AI

10:15 What are Neural Tube Defects?

16:30 Publications from the Ross Lab

21:00 The Ross Lab's Use of AI

30:00 Clinical Applications of Genetic Research

31:00 Spina Bifida Outcomes

32:00 Health Equity in Genetics

36:40 What's Next?

42:00 What's the future of AI in Medicine?

43:40 Advice for your Past Self

45:00 Advice for Medical Student/Physicians

48:00 Final Words of Wisdom

Intro Music - Windows96 - Caligula (song used with permission from artist).

Host: Madeline Ahern

Producer: Melanie Bussan

Cover Art: Saurin Kantesaria

Follow us on twitter @themamlpodcast Email us! [email protected] Looking for industry sponsors!

Description:  Neal Khosla is the founder and CEO of Curai Health, a digital health startup making big waves in the primary care space. To learn more, please visit curaihealth.com.  

1:00 Tell us about your path and how you came to the intersection of medicine and machine learning

13:15 - Most common patient demographic served

15:45 - Story of how Curai began. + history of medicine

29:00 - Can med + AI reason better than us? + vision for Curai

40:30 - When should patients go into clinic?

44:40 How has regulation affected you 

47:00 - How has mentorship shaped your path

53:20 - 3 questions i want to ask everyone

What are you most afraid of?

What do you believe in?

What gives you strength?

58:00- What do you want from the universe?

Intro Music - Windows96 - Caligula (song used with permission from artist).  

Host: David Wu @davidjhwu 

Producer: Aaron Schumacher @a_schu95 

Cover Art: Saurin Kantesaria  

Follow us on twitter @themamlpodcast Email us! [email protected] Looking for industry sponsors!

"Because Life needs Art to explicate its meaning,

and Art needs Technology to keep its edge bleeding."

Yvonne Lui, MD, is the associate chair of radiology of NYU Langone Health. Today we discuss FastMRI, the interesting collaboration between NYU and Facebook AI. We explore how machine learning can enhance image reconstruction following an MRI scan. 

0:00 Background on MRI

2:36 Intersection of Medicine and Machine Learning for Dr. Lui

6:40 Current Research Projects 

11:40 MRI partnership with Facebook AI & MRI Image reconstruction 

17:12 Models for research in clinical trials

21:30 Why Facebook is interested in this problem

24:15 Further information on the Machine Learning MRI reconstruction

27:45 Academic & Industry Collaboration 

35:00 Hesitancy in collaborating with industry

37:05 What areas of AI are Dr. Lui interested in 

38:45 Future of AI and Medicine

40:30 Radiology and Automation

43:00 Dr. Lui's balance between clinical work, research, and administrative work

48:20 What advice would you give to yourself early on in your career. 

Host: David Wu @davidjhwu

Producer: Aaron Schumacher @a_schu95

Cover Art: Saurin Kantesaria

David Lindsay is the CEO of Oncora, a data, documentation, and personalized care solution for specialty oncology. Oncora is currently implemented in many major hospital systems, including Northwell Health, MD Anderson, Mass General Children's, and Scripps Health. David founded the company during his MD/Ph.D. training at the University of Pennsylvania.

0:00 Introduction

1:15 David Lindsay tells his story

5:00 Initial Idea for a company bringing AI to oncology

7:35 When did David decide to start the company

10:25 Balancing being a CEO and a medical student at the same time

12:30 The early challenges in starting the company

14:30 The initial offerings of the company

17:50 Obtaining initial data sets

20:25 Initial funding for the company

24:45 A use case to predict hospitalization

27:10 How are these AI technologies regulated

30:00 How do clients pay for this technology

32:45 Tracking quality metrics

36:00 Integrating with an EHR

37:30 Further development of the product

41:35 Next steps for Oncora

43:55 Industry vs Academia

47:30 Next for AI in 10 - 20 years

48:20 Advice for yourself 20 years ago

50:00 Advice for students in industry

53:30 David’s plans for the future

Host: David Wu @davidjhwu

Producer: Aaron Schumacher @a_schu95

Cover Art: Saurin Kantesaria

Carmen Aguirre is a 4th-year medical student, visual jockey (VJ), and NFT artist. Here we sit down and discover what pushes her to continue developing her passions for medicine and artificial intelligence. You can find more info about her work here: https://linktr.ee/Neurite 0:00 Alex gives some background on NFT's 

2:50 Background and Initial Involvement with NFT's 

5:50 Seeing stigma around mental health conditions 

9:10 Building a community around NFT's 

9:40 The process of creating NFT's 

13:20 Working for Ariana Grande 

15:10 Working as a DJ and in music while in medical school 

21:10 "Work is my life" - how Carmen balances the commitments 

22:10 Time management 

24:35 How a creative outlet benefited Carmen's mental health 

27:25 Raising Money for mental health charities through NFT's 

30:30 Going from animation to the drop process 

34:00 Return of live music, graduating medical school and residency 

36:45 The average medical student compared to the average 24-year old musician 

39:15 How will technology change medicine in 10-20 years 

41:00 Advice you would have given yourself going into your 20's

Interviewer: David Wu

Producer: Aaron Schumacher

Art: Saurin Kantesaria

In our first ever two-interviewee episode we welcome Doctors Shannon Haymond and Christopher McCudden.

Dr. Haymond is the Vice Chair for Computational Pathology and Director of Mass Spectrometry at Lurie Children’s hospital of Chicago and an Associate Professor of Pathology at Northwestern University Feinberg School of Medicine.

Dr. McCudden is the Vice Chair for the Department of Pathology & Laboratory Medicine at the University of Ottawa and a Clinical Biochemist in the Division of Biochemistry at The Ottawa Hospital.

They are co-authors of "Rise of the Machines: Artificial Intelligence and the Clinical Laboratory." This article details the potential uses for artificial intelligence within the clinical laboratory. From newborn screening and inborn errors of metabolism to toxicology screens and everything in between, this article not only provides insight into the future of artificial intelligence, but also a peek into the clinical laboratory.

In this interview, we talk about the many paths to understanding and working with machine learning, from Dr. Haymond who is classically trained, to Dr. McCudden, who taught himself "R." We discuss the use of mass spectrometry, genomics screenings, and other current laboratory techniques and how they might be aided by artificial intelligence.

We hope that this interview gives you a comprehensive look into the world of laboratory medicine that is at the heart of all healthcare systems. Thank you and enjoy!

1:37 What are Clinical Laboratories?

3:20 Breaking up with Excel - Dr. Haymond’s Journey

5:49 All Specialties use the Lab

7:40 Learning “R” - Dr. McCudden’s Journey

11:31 Clinical Mass Spectrometry

15:45 Newborn Screening and Genetic Testing

17:41 Clinical Biochemistry

21:56 Artificial General, Narrow, and Super Intelligence

23:40 AI in Genomics

29:55 Open Source or Proprietary?

32:33 Future of AI In the Clinical Lab

38:50 Advice to Listeners