The Next ReGeneration Podcast

In the latest episode of the Next Regeneration podcast, hosts Anina and Elena talk to Nikos Donos, who shares his more than 20 years of experience using biologics for tissue regeneration and discusses the potential and limitations of different biologic agents. Much of his research has contributed to a better understanding of how different biological factors can enhance specific pathways in the healing cascade, and therefore the importance of using them in a biologically oriented way to maximise their efficacy.

In this interview, Donos reflects on how patient selection will become increasingly important. In this respect, biologics that specifically enhance the resolution of inflammation may likely be beneficial in patients with diseases with inflammatory pathogenesis, such as diabetes. Tune in now to discover expert insights on leveraging biologics for optimal tissue regeneration.

In the latest episode of the Next Regeneration podcast, hosts Anina and Elena talk to Lorenzo Tavelli about his inspiring journey as a periodontist and clinical researcher. Tavelli began his career in Milan, Italy, and then pursued his academic path at the University of Michigan, eventually moving on to the Harvard School of Dental Medicine. Along the way, he has published a remarkable number of influential papers on periodontal regeneration and implant dentistry.

In this interview, Tavelli talks about how he became interested in periodontology and the important role his mentors played in shaping his career. He also discusses his belief that the future of dentistry will be more personalised, incorporating new biomaterials, advanced tissue engineering techniques and artificial intelligence.

In the latest episode of the Next Regeneration podcast, hosts Anina and Elena talk to Nagihan Bostanci, the Head of Internationalization in Dentistry and Professor of Inflammation Research in Periodontology at the Karolinska Institute in Stockholm, Sweden. Together they discuss her research on salivary biomarkers. 

Bostanci suggests that salivary markers could revolutionise patient care by profiling risk, monitoring over time, and providing prognostic insights. 

While a single marker may not be sufficient for point-of-care diagnostic tests, she reveals how biomarker analysis could complement existing clinical and radiographic tools. Bostanci also discusses the future of microfluidic devices and the potential of wearable tech for patient monitoring.

In the latest episode of the Next Regeneration podcast, hosts Anina and Elena talk to Nikos Mattheos about his remarkable journey as a periodontist, researcher, and academic teacher. Starting his career in Athens, Greece, Mattheos made significant contributions at the University of Malmö, Bern, and Hong Kong, where he published groundbreaking research in implantology.

He explains how his early interest in digital technologies led to his research projects. An advocate of prosthetically driven implant placement, Mattheos shares his insights on the vital link between periodontology and prosthodontics. He also offers tips for successful implant crown design and offers a glimpse of future trends in implantology.

In the latest episode of the Next Regeneration podcast, hosts Anina and Elena talk to Frank Schwarz about his groundbreaking work on peri-implant diseases. Schwarz shares his extensive experience in the treatment of peri-implantitis and emphasises the importance of prevention and personalised care programmes.

He discusses the various risk factors for developing peri-implantitis and potential prevention strategies. Schwarz also reflects on the differing views of patients and clinicians on what constitutes successful treatment. Finally, he offers his vision for the future of peri-implant disease research. While he doubts the feasibility of developing implants that are completely resistant to peri-implantitis, he believes the future lies in careful patient selection and modulation of the host immune response.

The use of host modulators represents a true paradigm shift in the way we think about treating inflammatory diseases. In the current episode of the Next Regeneration Podcast, hosts Anina and Elena interview Hatice Hasturk about her pioneering work on specialized pro-resolving lipid mediators (SPMs) for treating periodontal diseases, along with her team.

Their approach represents a significant shift in how we handle inflammation, aiming for active resolution rather than suppression. The results of her translational research are promising and suggest that these modulators may not only target local inflammation but also have systemic effects, potentially breaking the link between periodontitis and systemic diseases. It's serious progress in the fight against inflammatory disorders.

A few years back 3D printing in dentistry sounded like science fiction. Today 3D printing allows to offer individualized treatments to patients. For the current episode of the Next Regeneration podcast hosts Anina and Elena meet Florian Thieringer, who is pioneering 3D printing in dentistry. 

As a clinician and researcher he provides first hand insights into the practical applications of 3D printing technology. He highlights materials that are suitable for 3D printing and explains the clinical scenarios, in which in they could be used. Not missing is the glimpse into the future of 3D printing in dentistry.

Dive into the world of statistics in dentistry with our two hosts Anina and Elena and their guest Cláudio Mendes Pannuti. He is Associate Professor in the Department of Periodontics at the University of São Paulo (Brazil) and in this podcast he talks about his passion for statistics. 

Starting with his journey into statistics, he stresses the importance of accessibility of statistical knowledge to students. He strongly advocates the involvement of statisticians in clinical trials and explains why understanding the disparity between statistical significance and clinical relevance is key. On top of that he provides valuable insights into sample size calculation and how to improve the quality of research manuscripts. 

Join hosts Anina and Elena in the latest episode of the Next ReGeneration Podcast for an engaging conversation with Danae Apatzidou, Associate Professor at the Department of Preventive Dentistry, Periodontology and Implant Biology at the Aristotle University of Thessaloniki (Greece). 

Apatzidou shares her expertise and passion for stem cell therapy in the field of oral regeneration. She explains the complex mechanisms of stem cells and how they are likely to induce the regeneration of missing tissue. While preclinical advances in tissue engineering are promising, there are still significant challenges at the clinical level, which Apatzidou discusses in more detail in this podcast. She concludes by presenting exciting future prospects in stem cell research.

Join hosts Anina and Elena on the Next ReGeneration Podcast for a coffee talk with Gustavo Avila Ortiz, the Editor-in-Chief of the International Journal of Periodontics & Restorative Dentistry. Discover the details of running a scientific journal as they discuss what happens from the moment an author hits the "submit" button to when their article is published.

Avila Ortiz shares insights into his role as a gatekeeper and coordinator in an environment where timely management of submitted papers can be a challenging. He highlights the importance of peer review and discusses how anonymity plays a crucial role in this process. Additionally, get a sneak peek into the future of scientific journals, especially in the context of digitalisation. 

 Tune in for a fascinating discussion on the behind-the-scenes of the academic publishing world.