Welcome to The Nonlinear Library, where we use Text-to-Speech software to convert the best writing from the Rationalist and EA communities into audio. This is: List of Lists of Concrete Biosecurity Project Ideas, published by Tessa on July 16, 2022 on The Effective Altruism Forum.
I was working on my own list of biorisk reduction project ideas, and ended up creating this list of lists, which seemed silly not to share.
I have quoted a few words describing each project, but it’s well worth clicking through to the original lists. None of them describe projects for longer than two pages, and most for a paragraph or so. Several of the EA Forum posts also contain links for getting in touch with teams working on these projects. If you’re interested in that, you might also want to fill in the longtermist census.
In general, I am so tired of people dying in pandemics. It does not necessarily make me optimistic to see all these project ideas― the world should already be much better at this, and there is so much work to be done. However, it does make me feel hopeful: the world can be much better, and there are projects that you could work on to help it become so.
Concrete Biosecurity Projects (some of which could be big)
January 2022 EA Forum Post
Early Detection Center
Early detection of a biothreat increases the amount of time we have to respond (e.g. designing tailored countermeasures, using protective equipment, heading to bunkers, etc)
See also: Nucleic Acid Observatory announcement from Will Bradshaw, Anjali Gopal, Mike McLaren, related post from Jeff Kaufman
Super PPE
it seems plausible that with good materials science and product design we could come up with next-generation PPE that is simultaneously highly effective in extreme cases, easy to use, reliable over long periods of time, and cheap/abundant.
Medical countermeasures
“radically improved medical countermeasures against GCBR-class threats, either by 1) producing targeted countermeasures against particularly concerning threats (or broad-spectrum countermeasures against a class of threats), or by 2) creating rapid response platforms that are reliable even against deliberate adversaries
See also: Alvea Vax announcement from Kyle Fish
BWC Strengthening
there is more scope for creative ways of strengthening the treaty (e.g. whistleblowing prizes), or creating new bilateral agreements and avoiding bureaucratic gridlock
Sterilization technology
Sterilization techniques that rely on physical principles . have the advantage of being broadly applicable, difficult to engineer around, and having little dual-use downside potential
See also: post on UV-C air purifiers
Refuges
specially designed refuges that safeguard against catastrophic pandemics
See also: Fønix: Bioweapons shelter project launch, Help Us Make Civilizational Refuges Happen from Linch Zhang and Ajay Karpur
Future Fund Project Ideas
As of July 2022
(I have not repeated ideas that pull directly from the above post, though the FTX write-ups are not word-for-word identical)
Crisis-aware regulation for global catastrophic biological risks
public health measures that would have a poor risk-benefit balance in normal times may be warranted or even critical in a crisis in which the benefits to eradicating or delaying a public health threat are unusually large” (link)
See also: original Project Ideas Competition submission by Mackenzie Arnold, with contributions by Kyle Fish
Rapid development and approval of emergency vaccination and therapeutics
imagine a team of high-powered vaccine developers, large-scale manufacturing capability on standby, and ready-to-go infrastructure for rapid human challenge trials in a regulatorily compliant manner” (link)
New ideas for mitigating biotechnology misuse
July 2022 EA Forum Post
Record-keeping for strong attribution
a record-based system for strong attribution of biological agents may be a powerful mechanism to deter biological weapons development and use”
Responsible access to genetic s...