According to UNAIDS, 33.4 million people are living with HIV worldwide, and approximately 2.7 million new infections occurred in 2008. For every two people who start treatment, five more are infected. Undoubtedly, this global epidemic requires a comprehensive, multisectoral approach that expands access to prevention, care, and treatment.America is leading the fight against global HIV/AIDS through the U.S. President's Emergency Plan for AIDS Relief (PEPFAR) – the largest commitment by any nation to combat a single disease internationally in history. The human impact of America’s investments in partner nations’ efforts is profound. Through PEPFAR, the United States has directly supported life-saving antiretroviral treatment for over 2.4 million people, and care for more than 11 million people with care and support programs, including more than 4 million orphans and vulnerable children. PEPFAR’s efforts around prevention of mother-to-child transmission programs have allowed nearly 340,000 babies of HIV-positive mothers to be born HIV-free. PEPFAR is the cornerstone and largest component of the President’s Global Health Initiative, which supports partner countries in improving health outcomes through strengthened health systems. Responsible for overseeing US-sponsored programs to combat the HIV/AIDS epidemic worldwide, Ambassador Eric Goosby joins the Council to discuss the Obama Administration’s commitment to the fight against global AIDS. Ambassador Goosby has over 25 years of experience with HIV/AIDS, ranging from his early years treating patients at San Francisco General Hospital when AIDS first emerged, to engagement at the highest level of policy leadership.