A Podful of Pediatrics

The One Where We Talk About Pneumococcal


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  1. Weiser JN, Ferreira DM, Paton JC. Streptococcus pneumoniae: transmission, colonization and invasion. Nat Rev Microbiol 2018; 16:355.
  2. Perin J, Mulick A, Yeung D, et al. Global, regional, and national causes of under-5 mortality in 2000-19: an updated systematic analysis with implications for the Sustainable Development Goals. Lancet Child Adolesc Health 2022; 6:106.
  3. World Health Organization. Pneumococcal conjugate vaccines in infants and children under 5 years of age: WHO position paper – February 2019. https://www.who.int/immunization/policy/position_papers/pneumococcus/en/ (Accessed on September 08, 2020). 
  4. Centers for Disease Control and Prevention. Pneumococcal Disease Surveillance and Trends. https://www.cdc.gov/pneumococcal/php/surveillance 
  5. Baxter R, Aukes L, Pelton SI, et al. Impact of the 13-Valent Pneumococcal Conjugate Vaccine on Invasive Pneumococcal Disease After Introduction Into Routine Pediatric Use. J Pediatric Infect Dis Soc 2021; 10:141.
  6. Tseng HF, Sy LS, Liu IL, et al. Postlicensure surveillance for pre-specified adverse events following the 13-valent pneumococcal conjugate vaccine in children. Vaccine 2013; 31:2578.
  7. Orenstein W, Offit PA, Edwards KM and Plotkin SA. Pneumococcal conjugate vaccine and pneumococcal common protein vaccines, in Vaccines, 8th Edition, 2024, 826-868. 
  8. The complexity of serotype replacement of pneumococci Human Vaccine Immunotherapy. 2019 Jun 13;15(11):2725–2728 
  9. https://www.nvic.org/disease-vaccine/pneumococcal/vaccine-history
  10. https://www.bradspellberg.com/vaccine-rcts?utm_source=substack&utm_medium=email

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A Podful of PediatricsBy Joanne Smith, Corinda Hankins