In 62 games the San Francisco 49ers lead the Arizona Cardinals 33-29 overall, all games played in the regular season. Sunday's the season FINALE and San Francisco defeated Arizona in Mexico City earlier this season. The 2022 NFC West champions are 12-4 with three different quarterbacks this season starting. Arizona will have their fourth quarterback starting as they're coming off a loss while Brock Purdy and the 49ers are coming off a win in week XVII.

This will be the 51st installment of this rivalry as the Seahawks and Geno Smith won the first meeting of the season against the Los Angeles Rams. Baker Mayfield was a Panthers when that game happened, however. The Seahawks in a must win situation to stay alive for the tournament and the Rams they're champions until the tournament begins Saturday January 14th, 2023 then their reign is officially done.

Los Angeles won the first meeting of the season against these Broncos on M.N.F. Russell Wilson would love to end the year on some what of a high note by defeating the Chargers. Justin Herbert and the Chargers are bound for a road wild card game in two weeks, this will be the 127th installment of this series. L.A. coming off a win and Denver's coming off yet another loss.

The Washington Commanders are eliminated from the tournament and play the role of spoilers vs. Dallas this Sunday. Dak Prescott and the boys look to improve their seeding if that will dow somehow opens. The Commanders will give rookie quarterback Sam Howell his 1st career start as Washington has absolutely nothing to lose in the 126th meeting of all time between these two NFC East rivals to end the 2022 NFL Season.

Philadelphia won the first meeting of the season by a wide margin against the New York Giants. The Eagles are without Jalen Hurts for a third at the recording of this prediction show. The G-men will have Daniel Jones. The Giants destroyed the Colts in week XVII, while the Eagles suffered their 2nd consecutive loss with Gardner Minshew III as their starting quarterback. This game is very pivotal for NFC TOURNAMENT seeds for Philly. The 2023 tournament begins next weekend. This is the 182nd installment of this series.

Minnesota defeated the Bears in their first meeting of the year. Kirk Cousins and the 2022 NFC North Champions are coming off a loss in week XVII and the Bears lost last week as well. Chicago will also start Nathan Peterman at quarterback as this is the 124th installment of this series and the Vikings are playoff bound win or lose in week XVIII.

Cincinnati leads this divisional series 28-25 overall against Baltimore. The Ravens won the first game of the season and it'll be Tyler Huntley for Baltimore vs. calm, cool Joe Burrow for the Bengals. Damar Hamlin's tragic injury postponed Monday night's game vs. Buffalo and the Ravens lost in week XVII on S.N.F. to the Pittsburgh Steelers.

With Buffalo having to postpone this past M.N.F. game against the Bengals, it's a great thing that they defeated the Patriots in the first meeting. Josh Allen and Bills will try to beat Mac Jones and his Patriots somehow in the wake of the tragic Damar Hamlin injury from Monday night. The Patriots are coming off a win however and this is the 127th installment of this division series.

The Panthers won their first meeting against the Saints this season. Andy Dalton leads New Orleans this final NFL Sunday while Sam Darnold leads the Carolina Panthers. This will be the 57th installment of this NFC South rivalry as the Saints are coming off a road win and the Panthers are coming off a road loss in week XVII.

The Houston Texans will finish the season on the road to face their rivals, the Indianapolis Colts. Both teams eliminated from postseason contention and the first game ended in a tie. The 43rd installment of this series is a Texas 2 quarterback system vs. Sam Ehlinger of the Colts, getting his 2nd career start in the season finale'.