In only the 17th meeting of all time between Patrick Mahomes II Chiefs' & the Jacksonville Jaguars. This will be the final game of week V on ESPN in prime time. Trevor Lawrence & his Jaguars will dominate the Chiefs to defense to the extent we've never seen. Or will they? The Chiefs and Jags won their week IV games, and BOTH these teams need to continue their winning streaks especially Jacksonville, more so than Kansas City.

This week's prime time game has some perks as we see Josh Allen & his Bills for the second time on Sunday night & we get Drake Maye & his Patriots with new head coach & former player Mike Vrabel. A new chapter to this rivalry & in the 132nd installment what does the outcome look like as there was already one epic prime time game to begin week V! [TNF].

Games on NBC.

Only the 13th meeting ever between the Los Angeles Chargers & the Washington Commanders to end week V day games this first of October. The game is on FOX & it'll be explosive as Justin Herbert will go head-to-head with Marcus Mariota. A lot of starters out in this game for Washington & this is another early season tough road game. Chargers lost to the Giants in week IV while the Commanders lost to the Falcons.

The 14th meeting of all time between the Kings of the motor city & the Tigers of the concrete jungle. We'll have the battle of a struggling Bengals team lead by backup Jake Browning going head-to-head with Jared Goff of the Detroit Lions in the even more famous 4:25 PM window for the NFL. Week IV showed Detroit serious and Cincinnati silly as the Bengals lost their week IV contest & Detroit roared.

Only the 16th meeting ever between Baker Mayfield & his Buccs & the Seattle Seahawks. The Tampa Bay Buccaneers lost to the Super Bowl Champs while Seattle won against Arizona to start week IV. This game is on CBS in the famed 4:00 PM window.

The 13th meeting of all time between Kyler Murray's Cardinals & Cam Ward's Titans is on tap in week V, as both teams lost their week IV games. The Titans rookie Q.B. Cam Ward is looking at a long road to stardom as it doesn't get any easier to get the team their first win of the year. Kyler Murray & company look to take a 3-2 record into week VI. This game is on CBS @ 4:05 PM.

The New York Giants are meeting the New Orleans Saints for the first time since the 14-11 win by New Orleans. This is the 34th meeting in the history of the NFL & Spencer Rattler has to find a way to get his team their first win on the year. Rookie Jaxson Dart and his Giants are looking to win their second game of the year on the road in the Big Easy baby, home of Anthony Mackie! This is the final 1:00 game of the year. Games on CBS.

Geno Smith & his Raiders must find a way to win on the road in a hostile environment in the 23rd meeting of all time against Daniel Jones & his Colts. The Colts are coming off a win whole the Raiders are coming off a loss in their week IV adventure. This games on FOX as this Colts team could find themselves on a "VII Reasons Why" here on the Prophet's Picks VII season. Enjoy this duel and it will be a duel.

The 9th meeting of all time between Tua Tagovailoa & his Dolphins & Bryce Young the Panthers will be this Sunday in the 1:00 window. The Dolphins are coming off their first win of the season. The Panthers shutout the Falcons one week & in week IV get beat really bad. This games on FOX.

Lamar "Action" Jackson to miss his Baltimore Ravens hosting C.J. Stroud & his Houston Texans this Sunday in the 16th meeting of all time. The Texans are coming off their first win of the season in week IV while the Ravens will throw former Dallas Cowboys back-up Cooper Rush to the wolves called the Texans defense in this one. This game will be on CBS.