Life sciences knowledge center

The Pros of mRNA Compared with Recombinant Protein Regarding Passive Immunization

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  • Cell-free production
  • Uniform physiochemistry of drug substances
  • The same technology for all antibody formats
  • Potential for storage at ambient temperature
  • mRNA half-life confers improved pharmacokinetics
  • Accessibility of intracellular targets
  • Potentially improved tolerability due to patient-specific antibody modification
  • Opportunity to reduce systemic exposure by in situ synthesis
  • Potential of high antibody titers with low doses of drug substance

    • https://mrna.creative-biolabs.com/therapeutic-antibody-coding-mrna.htm

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    Life sciences knowledge centerBy Echo Han