The RTW Podcast

By RTW Investments, LP

We’re witnessing a healthcare revolution, as medical and science innovations transform the lives of millions. Join as we speak to bright scientific minds, inspiring company founders and healthcare

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FAQs about The RTW Podcast:

How many episodes does The RTW Podcast have?

The podcast currently has 17 episodes available.

The RTW Podcast episodes:

August 19, 2026 Redefining the Weight Loss Revolution Beyond GLP1s: Influential Voices in the New Food Economy
Americans spend $1.4 trillion a year on food, and a growing share of that spending is decided in the grocery aisle by people holding a phone. Hunter Stoler, the certified health coach behind Health with Hunter, joins RTW's Stephanie Sirota to discuss what nearly two million followers are putting in their carts and why the largest retailers are paying attention. From losing 50 pounds and keeping it off, to reading ingredient lists instead of front-of-box claims, to the arrival of “GLP-1 friendly” shelf tags that carry no agreed definition, this is a view of how consumer demand is reshaping what mainstream grocers choose to stock.
Podcast team
Producer & Editor: Tim Young
Production Coordinator: YingYu Lin
Cinematographer: Peter Garofalo
Executive Editorial Advisor: Stephanie Sirota
Editorial Advisors: Steve Alperin, Jim Heins
Theme Music: Yehezkel Raz
Featuring: Hunter Stoler, certified health coach and creator of Health with Hunter, moderated by Stephanie Sirota, Partner and Chief Business Officer at RTW Investments.
FOLLOW US
Love our podcast? Follow us on LinkedIn at RTW Investments, LP and check out our website for the latest updates and insights.
To make sure you never miss an episode, you can subscribe to the RTW podcast on Spotify, Apple Podcasts, Amazon Music, and most other podcast platforms.
Chapters
00:00 - Introduction
01:18 - The Thanksgiving wake-up call
02:53 - What made the weight loss stick
03:46 - Learning to shop, and what bad habits cost
06:43 - Choosing influence over the clinical path
08:56 - Obesity: willpower, environment, or the food supply
11:15 - Reading the ingredients, not the front of the box
12:32 - Better-for-you goes mainstream
14:16 - GLP-1s and the new shelf
15:23 - Protecting muscle and prioritizing protein
19:03 - Inside the grocery walkthrough
22:20 - Change requires change
Disclaimer
This interview was given by Hunter Stoler, certified health coach and creator of Health with Hunter, and moderated by Stephanie Sirota, Partner and Chief Business Officer at RTW Investments. Statements by RTW personnel reflect RTW's views and opinions as of the date of recording. All expressions of opinion are subject to change without notice and are not intended to be a forecast of future events or results. The views expressed by guests are their own, and their appearance on the program does not imply an endorsement of them or any entity they represent. Nothing in this episode is medical advice. Listeners should consult a qualified healthcare professional regarding their own health decisions.
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26min
July 20, 2026 Psilocybin on the Verge: Treating Depression at Compass Pathways
Treatment-resistant depression affects four million Americans, and until now, patients have had almost no options. Dr. Steve Levine of Compass Pathways joins RTW's Stephanie Sirota to discuss COMP360, a psilocybin-based therapy for treatment-resistant depression. From the science behind rapid and durable response, to the regulatory path, reimbursement infrastructure, and what's next for PTSD, this is a rare inside look at how the most promising new chapter in psychiatric medicine gets built.
PODCAST TEAM
Producer & Director: Devon Leaver
Editor: Dominique Guerra
Production Coordinator: Ying Yu Lin
Production Support: Annabelle Chan
Research Consultant: Connor Williams
Executive Editorial Advisor: Stephanie Sirota
Theme Music: Yehezkel Raz
Additional Music: APM Music
Featuring: Steve Levine, Chief Patient Officer of Compass Pathways, moderated by Stephanie Sirota, Partner and Chief Business Officer.
Don't forget to listen to part 1 of Stephanie's discussion, Psilocybin: Counterculture to Cutting-Edge Psychiatry.
FOLLOW US
Love our podcast? Follow us on LinkedIn at RTW Investments, LP and check out our website for the latest updates and insights.
To make sure you never miss an episode, you can subscribe to the RTW podcast on Spotify, Apple Podcasts, Amazon Music, and most other podcast platforms.
CHAPTERS
00:00 - Introduction
1:37 – Steve Levine & Compass Pathways
5:27 - The Treatment Resistant Depression Journey
9:42 - Who are the TRD Patients?
11:06 - Holding Psychedelics to the Same Standard
18:25 - Why PTSD Is the Next Frontier
21:01 - Lifestyle's Role in Treatment Durability
22:41 - Outro
DISCLAIMER
This interview was given by Steve Levine, Chief Patient Officer of Compass Pathways, and moderated by Stephanie Sirota, Partner and Chief Business Officer at RTW Investments. Statements reflect RTW's views and opinions as of the date hereof and not as of any future date. All expressions of opinion are subject to change without notice and are not intended to be a forecast of future events or results. The views expressed by guests are their own, and their appearance on the program does not imply an endorsement of them or any entity they represent.
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25min
June 22, 2026 Psilocybin: Counterculture to Cutting-Edge Psychiatry
Are psychedelics poised to transform mental health treatment? Connor Williams joins Stephanie Sirota for a deep dive into psilocybin, the science behind its effects on the brain, and its potential in treatment-resistant depression, PTSD, and other serious conditions. As clinical trials advance and FDA pathways take shape, psychedelics have moved from counterculture to clinic, raising critical questions for patients, clinicians, and investors alike.
PODCAST TEAM
Producer & Director: Devon Leaver
Editor: Dominique Guerra
Production Coordinator: Ying Yu Lin
Production support: Annabelle Chan
Executive Editorial Advisor: Stephanie Sirota
Research Consultant: Connor Williams
Theme music: Yehezkel Raz
Additional music: APM Music
Featuring: Senior Research Analyst, Connor Williams, and moderated by Stephanie Sirota, Partner and Chief Business Officer at RTW Investments
Stay tuned for part 2 of Stephanie's discussion on Psychedelics with Dr. Steve Levine, Chief Patient Officer at Compass Pathways.
FOLLOW US
Love our podcast? Follow us on LinkedIn at RTW Investments, LP and check out our website for the latest updates and insights.
To make sure you never miss an episode, you can subscribe to the RTW podcast on Spotify, Apple Podcasts, Amazon Music, and most other podcast platforms.
CHAPTERS
00:00 - Introduction
1:12 - Explaining Psilocybin
4:21 – Recreational Use to Medical Use
6:03 - Compass Pathways’ Story
11:18 - Getting Psychedelics to Patients
16:04 - Myth or Fact: Psilocybin
21:15 - What’s next for Psilocybin?
20:02 - Outro
DISCLAIMER
This interview was given by Senior Research Analyst, Connor Williams, and moderated by Stephanie Sirota, Partner and Chief Business Officer at RTW Investments. Statements reflect RTW's views and opinions as of the date hereof and not as of any future date. All expressions of opinion are subject to change without notice and are not intended to be a forecast of future events or results. The views expressed by guests are their own and their appearance on the program does not imply an endorsement of them or any entity they represent.
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25min
May 28, 2026 ASCO: The Biggest Event in Oncology
For decades, some cancers were a near-certain death sentence. Now, a new generation of cancer drugs—many coming from biotech, not big pharma—is changing that. RTW’s Chris Liu discusses ASCO 2026, and breakthroughs in pancreatic cancer, lung cancer, and other hard-to-treat tumors. What's driving the progress, why is it happening now, and what does it mean for the future of cancer care?
PODCAST TEAM
Producer & Director: Devon Leaver
Editor: Dominique Guerra
Production Coordinator: Ying Yu Lin
Production Support: Annabelle Chan
Production Assistant: Nicole M. Rosales
Executive Editorial Advisor: Stephanie A. Sirota
Research Consultant: Chris Liu
Research Consultant: Julia Harper
Research Consultant: Lauren Lee
Theme Music: Yehezkel Raz
Additional Music: APM Music
Featuring by Chris Liu, Senior Research Analyst, moderated by Stephanie Sirota, Partner, and Chief Business Officer at RTW Investments.
FOLLOW US
Love our podcast? Follow us on LinkedIn at RTW Investments, LP and check out our website for the latest updates and insights.
To make sure you never miss an episode, you can subscribe to the RTW podcast on YouTube, Spotify, Apple Podcasts, Amazon Music, and most other podcast platforms.
CHAPTERS
00:00 - Introduction
1:04 – The Evolution of Cancer Treatments
3:19 - Unmet Needs in Oncology
10:03 - Treating Pancreatic Cancer
14:20 - The Importance of ASCO
16:48 - The Rise of Chinese Biotech
21:54 - Trends in Oncology
23:42 - Outro
DISCLAIMER
This interview was given by Chris Liu, Senior Research Analyst, and moderated by Partner, and Chief Business Officer Stephanie Sirota, at RTW Investments. Statements reflect RTW's views and opinions as of the date hereof and not as of any future date. All expressions of opinion are subject to change without notice and are not intended to be a forecast of future events or results. The views expressed by guests are their own and their appearance on the program does not imply an endorsement of them or any entity they represent.
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25min
April 27, 2026 Women's Health: An Investing Whitespace
Menopause, perimenopause, and hormone replacement therapy (HRT) are reshaping the conversation around women’s health and longevity. OB/GYN Dr. Stephanie Lam explains the science, symptoms, and why women’s healthcare may represent a major investing whitespace.
PODCAST TEAM
Producer & Director: Devon Leaver
Editor: Dominique Guerra
Production Coordinator: Ying Yu Lin
Production support: Annabelle Chan
Executive Editorial Advisor: Stephanie Sirota
Theme music: Yehezkel Raz
Additional music: APM Music
Featuring: Dr. Stephanie Lam, OB/GYN, Carnegie Women’s Health, moderated by Stephanie Sirota, Partner, Chief Business Officer, RTW Investments, LP.
FOLLOW US
Love our podcast? Follow us on LinkedIn at RTW Investments, LP and check out our website for the latest updates and insights.
To make sure you never miss an episode, you can subscribe to the RTW podcast on Spotify, Apple Podcasts, Amazon Music, and most other podcast platforms.
CHAPTERS
00:00 – Introduction
00:55 - Dr. Lam’s Path to OB/GYN
2:01 - Defining Menopause and Perimenopause
5:05 - The Health Impact of HRT
8:08 - A Holistic View of Women’s Health
10:35 - GLPs and Women’s Healthcare
14:25 - Investment Whitespaces in Women’s Health
19:03 - Outro
DISCLAIMER
This interview was given by Dr. Stephanie Lam, OB/GYN at Carnegie Women’s Health in New York, and moderated by Stephanie Sirota, Partner, Chief Business Officer at RTW Investments, LP. Statements reflect RTW's views and opinions as of the date hereof and not as of any future date. All expressions of opinion are subject to change without notice and are not intended to be a forecast of future events or results. The views expressed by guests are their own, and their appearance on the program does not imply an endorsement of them or any entity they represent.
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21min
March 30, 2026 Gene Editing: From CRISPR to Curative Medicine
What if you could fix disease by rewriting DNA? From CRISPR to next-gen gene editing, Stephanie Sirota and Beam Therapeutics CEO John Evans break down base editing, prime editing, and the path to one-time cures.
PODCAST TEAM
Producer & Director: Devon Leaver
Editor: Dominique Guerra
Production Coordinator: Ying Yu Lin
Production support: Annabelle Chan
Executive Editorial Advisor: Stephanie Sirota
Research Consultant: Piratip Pratumsuwan
Theme music by: Yehezkel Raz
Additional music: APM Music
Featuring: John Evans, CEO and Board Member of Beam Therapeutics, moderated by Stephanie Sirota, Partner and Chief Business Officer at RTW Investments.
FOLLOW US
Love our podcast? Follow us on LinkedIn at RTW Investments, LP and check out our website for the latest updates and insights.
To make sure you never miss an episode, you can subscribe to the RTW podcast on Spotify, Apple Podcasts, Amazon Music, and most other podcast platforms.
CHAPTERS
00:00 – Introduction
1:15 – Gene Editing, Gene Therapy, Base and Prime Editing
4:18 – Challenges in Gene Editing
6:09 – In Vivo and Ex Vivo
9:33 – What is A1AT Deficiency?
13:44 – Safety in Gene Editing
15:52 – AI and Beam Therapeutics
21:25 – John Evans’ Journey into Biotech
23:06 – Outro
DISCLAIMER
This interview was given by John Evans, CEO and Board Member of Beam Therapeutics, and moderated by Stephanie Sirota, Partner and Chief Business Officer at RTW Investments. Statements reflect RTW's views and opinions as of the date hereof and not as of any future date. All expressions of opinion are subject to change without notice and are not intended to be a forecast of future events or results. The views expressed by guests are their own and their appearance on the program does not imply an endorsement of them or any entity they represent.
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25min
January 12, 2026 Biotech’s Next Era: Innovation and Commercialization
Rod Wong joins Stephanie Sirota to trace biotech's evolution. What forces built today’s innovation landscape, and what might the next decade reveal?
PODCAST TEAM
Producer & Director: Devon Leaver
Editor: Dominique Guerra
Production Coordinator: YingYu Lin
Production Support: Annabelle Chan
Theme music: Ganymede by Yehezkel Raz
Additional music: APM Music
Featuring: Rod Wong, Managing Partner and Chief Investment Officer at RTW Investments, moderated by Stephanie A. Sirota, Partner, Chief Business Officer at RTW Investments.
FOLLOW US
Love our podcast? Follow us on LinkedIn at RTW Investments, LP and check out our website for the latest updates and insights.
To make sure you never miss an episode, you can subscribe to the RTW podcast on YouTube, Spotify, Apple Podcasts, Amazon Music, and most other podcast platforms.
Learn more about 'Innovation is the Best Medicine' here.
CHAPTERS
00:00 – Introduction
1:22 – Gene therapy and biotech
4:51 – Rod Wong’s journey into biotech
9:55 – Rod Wong: Investor or Business Builder?
12:43 – Growing trends in biotechnology
15:36 – Generating Alpha in Biotech
21:54 – Looking forward for RTW
23:51 - Outro
DISCLAIMER
This interview was given by Rod Wong, Managing Partner and Chief Investment Officer at RTW Investments, and moderated by Stephanie A. Sirota, Partner, Chief Business Officer at RTW Investments. Statements reflect RTW's views and opinions as of the date hereof and not as of any future date. All expressions of opinion are subject to change without notice and are not intended to be a forecast of future events or results. The views expressed by guests are their own, and their appearance on the program does not imply an endorsement of them or any entity they represent.
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25min
December 01, 2025 The Split Vote: UroGen and the FDA
When an FDA panel held her company’s future in the balance, UroGen Pharma CEO Liz Barrett refused to fold, even with the odds stacked, a plunging stock, and one vote deciding it all.
PODCAST TEAM
Producer and Director: Devon Leaver
Editor: Dominique Guerra
Production Coordinator: YingYu Lin
Production Support: Annabelle Chan
Story Consultants: Partner & Research Analyst Tony Nguyen, and Chief Corporate Finance Officer, Chris Seiter.
Featuring: Liz Barrett, President & CEO of UroGen Pharma, moderated by Stephanie A. Sirota, Partner and Chief Business Officer at RTW Investments, LP.
FOLLOW US
Love our podcast? Follow us on LinkedIn at RTW Investments, LP and check out our website for the latest updates and insights.
To make sure you never miss an episode, you can subscribe to the RTW podcast on Spotify, Apple Podcasts, Amazon Music, and most other podcast platforms.
CHAPTERS
00:00 - Introduction
00:54 – Liz Barrett’s pharma journey
03:26 - UroGen: the product and the pipeline
08:31 - The FDA vote on UroGen
15:07 - UroGen and RTW’s relationship
18:42 - Liz Barrett’s leadership style
22:40 - Outro
DISCLAIMER
This interview was given by Liz Barrett, President & CEO of UroGen Pharma, and moderated by Stephanie A. Sirota, Partner and Chief Business Officer at RTW Investments, LP. Statements reflect RTW's views and opinions as of the date hereof and not as of any future date. All expressions of opinion are subject to change without notice and are not intended to be a forecast of future events or results. The views expressed by guests are their own, and their appearance on the program does not imply an endorsement of them or any entity they represent.
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24min
October 06, 2025 14 Months to Treatment: Breaking Records in Rare Disease Therapy
From a Thanksgiving night emergency to one of the fastest gene therapies ever deployed, this is the story of a family’s relentless pursuit to help their daughter, and how RTW Foundation made it possible.
This episode was recorded on June 11, 2025, and the clinical trial details discussed may have changed; please see ellysteam.org for the most current information on Elly’s case.
PODCAST TEAM
Producer & Director: Devon Leaver
Production Coordinator: YingYu Lin
Editor: Dominique Guerra
Research Consultants: Joe Katakowski, PhD, and Nicole Litt
Story Consultant: Samantha Darris
Theme music: Ganymede by Yehezkel Raz
Additional music: APM Music
Featuring: Michelle Krueger, Managing Director at Alvarez & Marsal Transaction Advisory Group, and the co-founder of Elly’s Team, moderated by Stephanie A. Sirota, Partner, Chief Business Officer at RTW Investments, LP.
FOLLOW US
Now you can follow along in the format you prefer. Watch the video feed of this podcast on YouTube or read the transcript at rtwfunds.com/podcasts.
To make sure you never miss an episode, you can subscribe wherever you get your podcasts. Follow us on LinkedIn at RTW Investments, LP and check out our website for the latest updates and insights.
CHAPTERS
00:00 - Introduction
01:16 – Elly’s Diagnosis
04:37 - Finding a treatment with RTW Foundation
09:42 - Elly’s journey: from research to treatment
14:50 - Becoming the first child to receive an IRF2BPL gene replacement therapy
17:17 - Expanding the clinical trial for NEDAMSS
19:12 - How to improve drug research and development
21:18 - Outro and disclaimer
DISCLAIMER
This interview was given by Michelle Krueger, Managing Director at Alvarez & Marsal Transaction Advisory Group, and the co-founder of Elly’s Team, and moderated by Stephanie A. Sirota, Partner and Chief Business Officer at RTW Investments, LP. Statements reflect RTW's views and opinions as of the date hereof and not as of any future date. All expressions of opinion are subject to change without notice and are not intended to be a forecast of future events or results. The views expressed by guests are their own, and their appearance on the program does not imply an endorsement of them or any entity they represent.
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23min
September 15, 2025 Losing Sleep and Lives: Matthew Walker on the Global Sleep Epidemic
Lack of sleep can be deadly and costly. Matthew Walker, author of NYT bestseller Why We Sleep and Stephanie Sirota explore the science of sleep, how not sleeping can hurt our health and economy, and the global sleep epidemic.
PODCAST TEAM
Producer: Devon Leaver
Editor: Dominique Guerra
Featuring: Dr. Matthew Walker PhD, Author of Why We Sleep: Unlocking the Power of Sleep and Dreams, moderated by Stephanie Sirota, Partner and Chief Business Officer at RTW Investments.
FOLLOW US
Love our podcast? Follow us on LinkedIn at RTW Investments, LP and check out our website for the latest updates and insights.
To make sure you never miss an episode, you can subscribe to the RTW podcast on Spotify, Apple Podcasts, Amazon Music, and most other podcast platforms.
CHAPTERS
00:00 - Introduction
00:46 - Matthew Walker’s journey into sleep science
03:01 - Understanding the different types of sleep
06:06 - How to deal with jet lag
08:22 - The effect of sleep on young adults
11:02 - The impact of sleep on productivity
14:13 - Analyzing the dream state
17:34 - Sleeping, dreaming, and the relationship with mental health
19:59 - The future of sleep studies
21:34 - Sleep as the foundation of health
23:58 - Outro and disclaimer
DISCLAIMER
This interview was given by Dr. Matthew Walker, Author of Why We Sleep, and moderated by Stephanie Sirota, Partner and Chief Business Officer at RTW Investments. Statements reflect RTW's views and opinions as of the date hereof and not as of any future date. All expressions of opinion are subject to change without notice and are not intended to be a forecast of future events or results. The views expressed by guests are their own, and their appearance on the program does not imply an endorsement of them or any entity they represent.
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25min

FAQs about The RTW Podcast:

How many episodes does The RTW Podcast have?

The podcast currently has 17 episodes available.