From a bitter Nobel Prize dispute to the fragile partnerships that nearly unraveled it all, this is the untold human drama behind insulin. A story marked by clashing egos, secret experiments, and credit denied, the path to this life-saving breakthrough was anything but straightforward.

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References:

1. The Discovery and Early Development of Insulin - University of Toronto Libraries
2. The discovery of insulin: a story of monstrous egos and toxic rivalries. By Kersten Hall
3. Frederick Banting, Charles Best, James Collip, and John Macleod - The archive of Science History Institute (Museum and Library)

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Music: Sourced from Pixabay and Udio

Produced by: Radin Alikhani

Instagram: @rxchronicles_

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Special thanks to the University of Michigan's Shapiro Library for providing the recording space for this episode.

Before the applause, there was resistance. Before the prize, uncertainty. Four names. One forgotten moment. A quiet revolution in medicine that changed the course of cardiovascular care—forever. This episode begins with a voice from 1975 and unfolds into something much bigger...

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References:

1. National Academy of Sciences. Biographical Memoirs: By Garabed Eknoyan. Washington, DC: The National Academies Press.
2. Beyer KH Jr (1977). Discovery of the thiazides: where biology and chemistry meet. Perspectives in biology and medicine, 20(3), 410–420. https://doi.org/10.1353/pbm.1977.0048
3. Drugs.com - Hydrochrolothiazide Patient Tips

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Music: Sourced from Pixabay and Udio

Produced by: Radin Alikhani

Instagram: @rxchronicles_

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Special thanks to the University of Michigan's Shapiro Library for providing the recording space for this episode.

Lithium was once just a remedy for gout and bladder stones—until a psychiatrist’s bizarre experiment changed everything. After World War II, John Cade injected urine from mentally ill patients into guinea pigs, hoping to uncover the biological roots of mental illness...

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References:

1. Cade J. F. (1999). John Frederick Joseph Cade: family memories on the occasion of the 50th anniversary of his discovery of the use of lithium in mania. 1949. The Australian and New Zealand journal of psychiatry, 33(5), . https://doi.org/10.1080/j.1440-1614.1999.00624.x
2. Shorter E. (2009). The history of lithium therapy. Bipolar disorders, 11 Suppl 2(Suppl 2), 4–9. https://doi.org/10.1111/j.1399-5618.2009.00706.x
3. Chiu, E., & Hegarty, R. M. (1999). John Cade: the man. The Australian and New Zealand journal of psychiatry, 33 Suppl, S24–S26. https://doi.org/10.1111/j.1440-1614.1999.00664.x
4. Draaisma, D. (2019). The serendipitous story of lithium. Nature, 572(7771), 584-585. doi:https://doi.org/10.1038/d41586-019-02480-0
5. Drugs.com - Lithium Patient Tips

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Music: Sourced from Pixabay and Musopen

Produced by: Radin Alikhani

Instagram: @rxchronicles_

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Special thanks to the University of Michigan's Shapiro Library for providing the recording space for this episode.

For years, we’ve heard the stories of famous artists, politicians, and scientists; even criminals—but what about the overlooked inventors whose discoveries saved lives and eased suffering?

In this introductory episode, I outline the vision, mission, and objectives that will guide the direction of this podcast.

Produced by: Radin Alikhani

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Instagram: @rxchronicles_

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Special thanks to the University of Michigan's Shapiro Library for providing the recording space for this episode.