In this episode, we sit down with Sam Greenfield, a PhD candidate studying DNA replication in yeast, to explore what happens when cells copy their genetic “book” and certain sections are unexpectedly delayed. Sam uses creative analogies to break down complex molecular biology and explains how these rare replication events may connect to cancer, development, and aging. We also hear about his unconventional path to grad school, from an organic chemistry meltdown to studying extreme microbes and working at a major biorepository. Along the way, we talk career pivots, industry vs. academia, and how to turn scientific curiosity into a career. It’s a fun conversation about persistence, passion, and finding your place in science.
Date Recorded: November 19, 2025
🛠️ Resources & Links Mentioned:
🎙️ Other episodes you may like:
https://open.spotify.com/episode/4LEl2fkT06Ru8e4Jg2fPtF?si=899ff8969f584a8c
https://open.spotify.com/episode/3rrD3M7oP4NDJ1dMFJYUVd?si=24ff8092502444be
✨ Connect With Us:
🎵 Credits:
Disclaimer:
The views and opinions expressed in this episode are those of the guests and hosts and do not necessarily reflect the official policy or position of The Science Bridge, Project Bridge Colorado, or CU Anschutz Medical Campus. The information provided is for entertainment and informational purposes only and should not be considered as professional advice. Always consult with a qualified professional for specific guidance.