In this episode of Think Small, Alex sits down with David Esposito, CEO of ONL Therapeutics, for a rare, behind-the-scenes look at the long, high-stakes journey of bringing a new drug to market. From university-born science and early discovery work to the realities of fundraising, clinical trials, and navigating investor expectations,

David breaks down how ONL is advancing a promising therapy to protect retinal cells and slow vision loss in age-related macular degeneration. It’s a candid, fast-moving conversation about innovation, risk, and the grit required to push life-changing treatments toward FDA approval.

Connect:

LinkedIn: https://www.linkedin.com/in/davidesposito2/

Website: https://onltherapeutics.com/

In this episode, RealKey founder Christopher Hussain joins the Think Small Podcast to reveal how his AI-powered “deal room” is transforming the mortgage industry. He breaks down how RealKey streamlines processing and underwriting by automating document collection, verification, and communication for every party involved—from borrowers and brokers to agents, employers, and insurers—all in one unified space.

Christopher shares the origin story behind the platform, its pivots, his unique background as the nation’s top mortgage originator, and how RealKey’s world-class team is building a more efficient, secure, and scalable future for lending. We also look ahead at RealKey’s broader ambitions in auto loans, financial services, and global expansion. A must-listen for anyone curious about the future of fintech and frictionless lending.

Connect:

LinkedIn: https://www.linkedin.com/in/christopherhussain/

Website:

Facebook: https://www.facebook.com/realkeyinc

In this episode, HR expert Karen Young of HR Resolutions joins the show to talk about what modern, human-centered HR really looks like. From dismantling the “department of no” stereotype to building culture through honest communication, personalized leadership, and understanding how people actually work, Karen offers a refreshingly real take on creating thriving workplaces.

She shares practical insights on performance, communication styles, remote culture, and why humor, empathy, and curiosity matter just as much as policy. We also look ahead at HR Resolutions’ exciting growth and Karen’s mission to elevate the HR profession. A must-listen for leaders who want HR to be a strategic advantage—not a buzzkill.

Connect:

LinkedIn: https://www.linkedin.com/in/karenayoungauthor/

Website: https://www.hrresolutions.com/

In this episode, Matt Greer of DMS Color—now evolving under the Gold Leaf Print & Packaging brand—shares how he helped transform a tiny basement print shop into a national operation serving major corporations with advanced digital printing, packaging, and their proprietary DigiFlow web-to-print platform.

Matt walks us through key breakthrough moments, from disrupting traditional print houses to expanding into sophisticated packaging solutions and navigating today’s shifting global supply chain. He also breaks down how Goldleaf scales, sells, engineers complex packaging, and what’s next as they prepare to launch a full direct-to-consumer platform. A fascinating look at how innovation, attention to detail, and smart scaling can reshape an entire industry.

Connect:

LinkedIn: https://www.linkedin.com/in/matthew-greer-0b75595/

Website: https://www.linkedin.com/company/gold-leaf-packaging/

Patrick McDonald of CMG joins the Think Small Podcast to share how he went from a corporate job to building a 30-property mobile home park portfolio, starting with a dilapidated 13-unit park he found near home. He walks us through the early hustle—digging up sewer lines, learning septic systems on the fly, flipping parks, landing seller-financed deals, and eventually quitting his job in the middle of 2020 to scale full-time.

Patrick breaks down the “own the land, not the home” model, managing parks from afar, creative financing strategies, and why manufactured housing is poised for massive growth thanks to new federal support and expanding lending options. A must-listen for anyone curious about real estate, cash-flow businesses, or building a portfolio from the ground up.

Connect:

Website: https://cmgparks.com/

LinkedIn: https://www.linkedin.com/in/patrickmcdonaldnml/

Nationwide Health CPR started with one retired firefighter’s drive to keep saving lives through education. In this Think Small episode, Jason Smith shares how that mission grew from Broward County, Florida, into a multi-state network providing CPR training every day across the country.

Jason also talks about their upcoming initiatives—from expanding AED access for homes and businesses to exploring short CPR training videos and even pet CPR in 2026. He discusses the importance of time in cardiac emergencies, how technology like PulsePoint and smartwatches help save lives, and why his team continues to focus on one simple goal: making lifesaving education available to everyone.

Connect:

Website: https://nationwidehealthcpr.com/

LinkedIn: http://tiny.cc/1clu001

After years of corporate marketing, Lior Krolewicz realized something was missing—the human side of business. In this episode, he shares how Yael Consulting brings big-brand strategy to entrepreneurs who just want results that matter. From saving a few hundred dollars to helping a business stay afloat, it’s work that feels real and rewarding.

From his early days learning Google Ads in 2009 to leading a hands-on team today, Lior explains why understanding the platform’s foundations—and truly caring about client success—makes all the difference.

Connect:

LinkedIn: https://www.linkedin.com/in/liork/

Website: https://www.yaelconsulting.com/

When you stop chasing deals and start chasing growth, everything changes. Philip Whitman joins Alex Reyes to share how curiosity, mentorship, and generosity built the foundation of Whitman Transition Advisors. He explains why showing up in the right rooms—and paying people more than you “have to”—isn’t just good business, it’s good leadership.

Their conversation moves from personal lessons to universal takeaways on networking, coaching, and culture. From listening to 75 podcasts a week to joining mastermind groups and coaching programs, Phil shows what it means to be a lifelong learner. His story is a reminder that growth isn’t just about scaling revenue—it’s about expanding who you surround yourself with and what you choose to learn.

Connect:

Website: https://whitmantransition.com/

LinkedIn: https://www.linkedin.com/in/philipwhitman/

How to save a business on the brink? Meet Ken Yager, the “surgeon” for struggling companies.

When a business is two weeks away from missing payroll, who do you call? For many, that lifeline is Ken Yager, Founder of Newpoint Advisors, known for stepping into crisis-mode and helping small to mid-sized companies avoid collapse. In this episode, host Alex Reyes sits down with Ken to unpack:

• What really happens inside a “business turnaround”
• The 13-week cashflow model every entrepreneur should know
• How Newpoint has saved over 14,000 jobs through fast, focused action
• Why sometimes the key to survival is doing less, not more

Whether your company’s thriving or treading water, this episode is a reminder on staying proactive before crisis hits.

Connect:

Website: https://newpointadvisors.us/

Email: [email protected]

In this episode, host Alex Reyes sits down with Greg Parsons, Owner and Managing Director of Sharpham Dairy, to explore how a career spent inside some of the world’s biggest food companies inspired him to go small — and build something more sustainable, transparent, and human.

• How Greg helped form a local food supply chain for one of Europe’s largest construction projects
• The creative pivots that kept his small dairy alive through COVID-19
• What it means to be the UK’s first B Corp-certified cheesemaker
• How small food producers can influence big industry change

Connect:

LinkedIn: https://www.linkedin.com/in/greg-parsons-a9209b5/?originalSubdomain=uk

Website: https://sharphamcheese.co.uk/our-story/