The UroGist

In this episode of The UroGist, host Dr. Mike Louie of UroGen is joined by Dr. Eugene Rhee, 2026 President of the American Urological Association (AUA), to discuss the future of urology and uro-oncology. Together, they discuss innovation, health policy, patient advocacy, and the evolving treatment landscape. Dr. Rhee also shares his goals and vision as AUA President and explores how collaboration, education, and joy can help shape the future of patient-centered care.

Episode References:

• American Urological Association (AUA) Website

For users listening from their desktop device, please click on the link below to access clickable show notes.

In this episode of The UroGist, host Dr. Mike Louie of UroGen is joined by Meri-Margaret Deoudes, CEO of the Bladder Cancer Advocacy Network (BCAN), and Dr. Mark Schoenberg, UroGen's Chief Medical Officer. Together, they examine unmet needs in bladder cancer care, discuss insights from BCAN's New Faces of Bladder Cancer report, and highlight the increasingly vital role of patient advocacy and industry collaboration in improving the patient experience and advancing the future of patient-centered bladder cancer care.

Episode References:

• The New Faces of Bladder Cancer 2026 Report

• BCAN Website

• Urology – Michael E. Rezaee, Katherine M. Mahon, Zhuo Tony Su, Kaylee M. Luck, John D. Seigne, Sunil H. Patel, Max Kates

• BMJ Open – Michael E. Rezaee, Katherine M. Mahon, Bruce J. Trock, The-Hung Edward Nguyen, Armine K. Smith, Noah M. Hahn, Sunil H. Patel, Max Kates

• Journal of Clinical Oncology – Scott T. Tagawa, Katie S. Murray, Bradley Alexander McGregor, Sarah P. Psutka, Karim Chamie, Maneesh Jain, Rewatee Gokhale, Emma Landau, Chelsie Anderson, Samuel Dooyema, Jeffrey D. Carter, Cherilyn Heggen Ladda, Kelly E. McKinnon

• UroToday – Sarah Psutka, Ashish Kamat

• The Journal of Urology – Ganesh S. Palapattu, Mary Ellen Haisfield-Wolfe, Joanne M. Walker, Karlynn Brintzenhofeszoc, Bruce Trock, James Zabora, Mark Schoenberg

• Cancer – Ganesh S. Palapattu, Patrick J. Bastian, Phillip R. Slavney, Mary Ellen Haisfield-Wolfe, Joanne M. Walker, Karlynn Brintzenhofeszoc, Bruce Trock, James Zabora, Mark P. Schoenberg

• Cancer Medicine – Kezia Reji Thomas, Catherine Joshua, Christine Ibilibor

For users listening from their desktop device, please click on the link below to access clickable show notes.

In this episode of The UroGist, host Dr. Mike Louie of UroGen is joined by Dr. Saum Ghodoussipour, Director of the Bladder and Urothelial Cancer Program at the Rutgers Cancer Institute and Assistant Professor of Surgery at Rutgers Robert Wood Johnson Medical School. Together, they dive into the nuances of maintenance therapy for the treatment of low-grade upper tract urothelial cancer (LG-UTUC), exploring long-term durability data and real-world evidence.

• Full Prescribing Information, Instructions for Pharmacy, and Instructions for Administration
• Important Safety Information

• ClinicalTrials.gov - Study Description

• Instructions for Administration

• Antegrade Administration

For users listening from their desktop device, please click on the link below to access clickable show notes.

In this episode of The UroGist, a podcast for urologists, by urologists, host Dr. Mike Louie of UroGen is joined by Dr. Katie Murray, Urologic Oncologist and Professor at NYU Langone Health and Grossman School of Medicine, and Chief of Urology at Bellevue Hospital, to discuss advancements in treating recurrent low-grade intermediate-risk non-muscle invasive bladder cancer (LG-IR-NMIBC). Dr. Murray offers insights into patient identification and treatment options. Dr. Murray is a consultant for UroGen.

• ClinicalTrials.gov - Study Description

• Full Prescribing Information, Instructions for Pharmacy, Instructions for Administration, and Patient Package Insert

• Important Safety Information

• UroGen Support™

For users listening from their desktop device, please click on the link below to access clickable show notes.

In this episode of The UroGist, a podcast for urologists, by urologists, host Dr. Mike Louie of UroGen is joined by Dr. Sandip Prasad, Director of Genitourinary Surgical Oncology, Vice-Chair of Urology at Morristown Medical Center/Atlantic Health System, and principal investigator of the ENVISION clinical trial, to discuss recurrent low-grade intermediate-risk non-muscle invasive bladder cancer (LG-IR-NMIBC) and the pivotal phase 3 ENVISION clinical trial. Dr. Prasad shares insights from the study, the burden of recurrence for patients, and what a new treatment option may mean for patients. This interview was recorded in 2024.

• ClinicalTrials.gov - The ENVISION Study

• Full Prescribing Information, Instructions for Pharmacy, Instructions for Administration, and Patient Package Insert

• Important Safety Information

For users listening from their desktop device, please click on the link below to access clickable show notes.

In this episode of The UroGist, host Dr. Mike Louie of UroGen is joined by Dr. Pascal de Caprariis, a patient with low-grade upper tract urothelial cancer (LG-UTUC) and an infectious disease specialist. Dr. de Caprariis shares his unique perspective as both a physician and a person living with LG-UTUC, discussing his diagnosis, treatment journey, and offering advice to others facing similar challenges.

Documents to link in episode description:

• JELMYTO Full Prescribing Information, Instructions for Pharmacy, Instructions for Administration, and Patient Package Insert

• JELMYTO Important Safety Information

• The OLYMPUS Study

• JELMYTO Instructions for Administration

• Antegrade Administration of JELMYTO

• The Journal of Urology – Surena F. Matin, Phillip M. Pierorazio, Nir Kleinmann, John L. Gore, Ahmad Shabsigh, Brian Hu, Karim Chamie, Guilherme Godoy, Scott G. Hubosky, Marcelino Rivera, Michael O'Donnell, Marcus Quek, Jay D. Raman, John J. Knoedler, Douglas Scherr, Christopher Weight, Alon Weizer, Michael Woods, Hristos Kaimakliotis, Angela B. Smith, Jennifer Linehan, Jonathan Coleman, Mitchell R. Humphreys, Raymond Pak, David Lifshitz, Michael Verni, Ifat Klein, Marina Konorty, Dalit Strauss-Ayali, Gil Hakim, Elyse Seltzer, Mark Schoenberg, and Seth P. Lerner

For users listening from their desktop device, please click on the link below to access clickable show notes.

In this episode of The UroGist, host Dr. Mike Louie of UroGen sits down with guest Dr. Yair Lotan, Chief of Urologic Oncology at UT Southwestern Medical Center and Medical Director of the Urology Clinic at UT Southwestern and Parkland Health and Hospital System for an in-depth look at data derived from real-world patient experiences, insights into the latest real-world evidence and how this information helps shape the future of urologic oncology.

Documents to link in episode description:

• JELMYTO Full Prescribing Information, Instructions for Pharmacy, and Instructions for Administration
• JELMYTO Important Safety Information

• The OLYMPUS Study

• JELMYTO Instructions for Administration

• Antegrade Administration of JELMYTO

• uTRACT Jelmyto Registry – NIH National Cancer Institute

• uTRACT Jelmyto Registry – ClinicalTrials.gov
• Pharmaceutical Medicine – Amit Dang
• The Journal of Urology – Surena F. Matin, Phillip M. Pierorazio, Nir Kleinmann, John L. Gore, Ahmad Shabsigh, Brian Hu, Karim Chamie, Guilherme Godoy, Scott G. Hubosky, Marcelino Rivera, Michael O'Donnell, Marcus Quek, Jay D. Raman, John J. Knoedler, Douglas Scherr, Christopher Weight, Alon Weizer, Michael Woods, Hristos Kaimakliotis, Angela B. Smith, Jennifer Linehan, Jonathan Coleman, Mitchell R. Humphreys, Raymond Pak, David Lifshitz, Michael Verni, Ifat Klein, Marina Konorty, Dalit Strauss-Ayali, Gil Hakim, Elyse Seltzer, Mark Schoenberg, and Seth P. Lerner
• The Journal of Urology – Solomon L. Woldu, Brett Johnson, Katie S. Murray, Hiroko Miyagi, Wade Sexton, Isamu Tachibana, Hristos Kaimakliotis, Joseph Jacob, Rian Dickstein, Jennifer Linehan, Alan Nieder, Marc Bjurlin, Daniel Heidenberg, Mitchell Humphreys, Saum Ghodoussipour, Marcus L. Quek, Michael O'Donnell, Brian Eisner, Surena Matin, Adam S. Feldman, and Yair Lotan
• Urologic Oncology – Solomon L Woldu, Craig Labbate, Katie S Murray, Kyle Rose, Wade Sexton, Isamu Tachibana, Hristos Kaimakliotis, Joseph Jacob, Rian Dickstein, Jennifer Linehan, Alan Nieder, Marc A Bjurlin, Mitchell Humphreys, Saum Ghodoussipour, Marcus L Quek, Michael O'Donnell, Brian H Eisner, Adam S Feldman, Surena F Matin, Yair Lotan
• Urologic Oncology – Joseph M Jacob, Solomon L Woldu, Jennifer Linehan, Craig Labbate, Kyle M Rose, Wade J Sexton, Isamu Tachibana, Hristos Kaimakliotis, Alan Nieder, Marc A Bjurlin, Mitchell Humphreys, Saum B Ghodoussipour, Marcus L Quek, Brett Johnson, Michael O'Donnell, Brian H Eisner, Adam S Feldman, Katie S Murray, Surena F Matin, Yair Lotan, Rian J Dickstein
• European Urology Focus – Jennifer Linehan, Josh Gottlieb, Solomon L Woldu, Craig Labbate, Kyle Rose, Wade Sexton, Hristos Kaimakliotis, Joseph Jacob, Rian Dickstein, Alan Nieder, Marc Bjurlin, Mitchell Humphreys, Saum Ghodoussipor, Marcus Quek, Michael O'Donnell, Brian H Eisner, Adam S Feldman, Surena F Matin, Yair Lotan, Katie S Murray
• The Journal of Urology – Adam S. Feldman, Solomon L. Woldu, Brett Johnson, Katie S. Murray, Hiroko Miyagi, Wade Sexton, Isamu Tachibana, Hristos Kaimaklotis, Joseph Jacob, Rian Dickstein, Jennifer Linehan, Alan Nieder, Marc Bjurlin, Daniel Heidenberg, Mitchell Humphreys, Saum Ghodoussipour, Marcus L. Quek, Michael O'Donnell, Brian Eisner, Yair Lotan, and Surena Matin

For users listening from their desktop device, please click on the link below to access clickable show notes.

In this episode of The UroGist, host Dr. Mike Louie of UroGen sits down with guest Dr. Jennifer Linehan, an Associate Professor of Urologic Oncology and Section Head of Urology Translational Research at the St. John's Cancer Institute in Santa Monica, CA to discuss the nuances of antegrade administration of an innovative treatment for low-grade upper tract urothelial cancer.

While discussing the OLYMPUS study, the episode refers to 84% durability [1] for 12 months for patients with low-grade upper tract urothelial cancer, which was found in interim data. The final durability of response data from the OLYMPUS trial for all 41 patients was 82% at 12 months. [2]

· JELMYTO Full Prescribing Information, Instructions for Pharmacy, and Instructions for Administration

· The OLYMPUS Study

· JELMYTO Instructions for Administration

· Antegrade Administration of JELMYTO

· uTRACT Jelmyto Registry – NIH National Cancer Institute

· uTRACT Jelmyto Registry – ClinicalTrials.gov

· Journal of Urologic Oncology – Joseph M Jacob, Solomon L Woldu, Jennifer Linehan, Craig Labbate, Kyle M Rose, Wade J Sexton, Isamu Tachibana, Hristos Kaimakliotis, Alan Nieder, Marc A Bjurlin, Mitchell Humphreys, Saum B Ghodoussipour, Marcus Quek, Michael O'Donnell, Brian H Eisner, Adam S Feldman, Surena F Martin, Yair Lotan, Katie S Murray

· European Urology Focus – Jennifer Linehan, Josh Gottlieb, Solomon L Woldu, Craig Labbate, Kyle Rose, Wade Sexton, Hristos Kaimakliotis, Joseph Jacob, Rian Dickstein, Alan Nieder, Marc Bjurlin, Mitchell Humphreys, Saum Ghodoussipor, Marcus Quek, Michael O'Donnell, Brian H Eisner, Adam S Feldman, Surena F Matin, Yair Lotan, Katie S Murray

[1] Lerner, Seth. Primary chemoablation of low-grade upper tract urothelial carcinoma using UGN-101, a mitomycin-containing reverse thermal gel (OLYMPUS): a prospective single-arm phase 3 trial. The Lancet Oncology, 2020

[2] Matin SF, Pierorazio PM, Kleinmann N, Gore JL, Shabsigh A, Hu B, Chamie K, Godoy G, Hubosky SG, Rivera M, O'Donnell M, Quek M, Raman JD, Knoedler JJ, Scherr D, Weight C, Weizer A, Woods M, Kaimakliotis H, Smith AB, Linehan J, Coleman J, Humphreys MR, Pak R, Lifshitz D, Verni M, Klein I, Konorty M, Strauss-Ayali D, Hakim G, Seltzer E, Schoenberg M, Lerner SP. Durability of Response to Primary Chemoablation of Low-Grade Upper Tract Urothelial Carcinoma Using UGN-101, a Mitomycin-Containing Reverse Thermal Gel: OLYMPUS Trial Final Report. J Urol. 2022 Apr;207(4):779-788. doi: 10.1097/JU.0000000000002350. Epub 2021 Dec 17. PMID: 34915741.

In this inaugural episode of The UroGist, host Dr. Mike Louie of UroGen Pharma welcomes guest Dr. Katie Murray, Professor at NYU Langone Health as well as the Chief of Urology Service at Bellevue Hospital Center, for an informative chat about personalized treatment, management, and subsequent challenges for low-grade upper tract urothelial cancer (LG-UTUC) patients.