When lovable nerds Gilbert and Lewis embark on their freshman year at Adams College, little do they realize the dangers that await them. They are beset by taunting from the jocks of Alpha Beta fraternity, which only worsens when the jocks accidentally burn down their house and toss the freshmen out of their dorm. To make matters worse, Lewis develops a crush on Betty Childs, popular sorority sister and the football quarterback's girlfriend. Joined by other misfits, the nerds form their own fraternity. Will they succeed in turning the tables and be taken seriously? Will Lewis win Betty's heart?