Scully is asked by Assistant Director Skinner to assist officials from the Center for Disease Control in determining the cause of a recent number of deaths in the Philadelphia area. All of the victims were African American and had lost their pigmentation, with their corpses looking albino-like. She finds the basic reason for the loss of pigmentation - their pituitary glands were necrotic - but not the actual cause. Mulder for his part thinks there is something far more sinister at work and contacts Marita Covarrubias at the U.N. who tells him of a similar incident on flight from West Africa some months before.

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