In this episode, Dr. José García-Tirado joins us to discuss his work with the individualization of behavior patterns (including eating and exercise patterns) from CGM, insulin pump, and activity tracker data.

Click on the links below for some of his recent papers. 

Mapping data to virtual patients in type 1 diabetes

Anticipation of Historical Exercise Patterns by a Novel Artificial Pancreas System Reduces Hypoglycemia During and After Moderate-Intensity Physical Activity in People with Type 1 Diabetes

In this episode, Amelia Linnemann joins us to speak about the mechanisms of adaptive stress response in the pancreatic islet. Dr. Linnemann provides us with some insight about a recent publication, Pancreatic beta cell autophagy is impaired in type 1 diabetes.

Learn more about her work here

In this episode, Qiufu Ma joins us to discuss the ongoing research taking place in his lab. Dr. Ma's lab focuses on two lines of research: mapping pain pathways and exploring how acupuncture works. Tune in to hear Dr. Ma discuss one of his recent publications, Somato-Autonomic Reflexes of Acupuncture.

Learn more about Ma Lab here

In this episode, Gaël McGill joins us to discuss ways in which cell and molecular visualization can inform the research and discovery process. Dr. McGill is the founder of Digizyme. Digizyme's mission is to innovate at the intersection of science, technology, art and learning to create accurate and effective visual context for understanding science.

Follow the link below for an animation video that explains the fundamentals of SARS CoV-2 membrane binding.

SARS CoV-2 animation

To learn more about Digizyme, click here

In this episode, David Wraith joins us to discuss his profound knowledge on autoimmunity and immunotherapy. His research team has revealed mechanisms whereby autoreactive T-cells escape deletion in the thymus and thus appear in the repertoire of all individuals. He also demonstrated that autoreactive T-cells can be silenced by suitable administration of fragments of their protein targets.

In this episode, Jessica Gibson joins us to discuss the latest work at Ariel Precision Medicine. Ariel is a health technology company seamlessly integrating complex genetics into clinical decision-making, empowering doctors and patients to prevent, mitigate or even reverse disease progression. Ariel's initial focus is pancreatic diseases including pancreatitis, diabetes and pancreatic cancer.

Learn more about Ariel Precision Medicine here

In this episode, Josh Nicholson joins us to discuss how to use Scite. Scite is a deep learning platform that evaluates the reliability of scientific claims by citation analysis. Scite is a very valuable tool for all researchers. 

Smart citations for better research.

Checkout scite here!

In this episode, Bart Roep joins us to discuss the latest progress at City of Hope in the quest to cure type 1 diabetes. Early 2020 marked a milestone for science funded by The Wanek Family Project. Results had come in from a first-in-humans clinical trial testing a “reverse vaccine” for type 1 diabetes developed by Roep and his colleagues. The research showed the treatment to be safe and even indicated possible benefit as a therapy.

In this episode, Scott Soleimanpour joins us to discuss his fascinating research taking place at the University of Michigan. Dr. Soleimanpour provides details about a recent publication, Mitophagy protects β cells from inflammatory damage in diabetes. 

Dr. Soleimanpour's lab focuses on the molecular and genetic regulation of the mitochondrial life cycle, with a focus on mitophagy, a pathway to dispose of unhealthy or damaged mitochondria. Our studies also concentrate on novel genetic targets affecting the mitophagy pathway, which are also associated with diabetes in humans, through studies in cellular and mouse genetic model systems, as well as isolated human islets. 

To learn more about Soleimanpour's lab follow the link below:

Soleimanpour Lab

In this episode, Darleen Sandoval joins us to discuss her research and recent publication, Updating the Role of α-Cell Preproglucagon Products on GLP-1 Receptor–Mediated Insulin Secretion.

Dr. Sandoval's current work utilizes basic research strategies to focus on two general themes of research. The first goal is to gain understanding on the role of a gastrointestinal peptide, GLP-1, in the gut-brain axis to regulate energy and glucose homeostasis. The second is to gain understanding on the adaptations of the gut-brain axis with bariatric surgery and how this leads to the profound weight-loss and improvements in glucose and lipid homeostasis seen with these surgeries.